Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Claudia Masini d‘Avila-Levy"'
Autor:
Vítor Ennes-Vidal, André Luis Souza dos Santos, Marta Helena Branquinha, Claudia Masini d’Avila-Levy
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 117 (2022)
The treatment for tropical neglected diseases, such as Chagas disease (CD) and leishmaniasis, is extremely limited to a handful of drugs that suffer from unacceptable toxicity, tough administration routes, like parenteral, and increasing treatment fa
Externí odkaz:
https://doaj.org/article/044acda820c94663addf0a923c8dd70d
Autor:
Carolina Boucinha, Valter Viana Andrade-Neto, Vítor Ennes-Vidal, Marta Helena Branquinha, André Luis Souza dos Santos, Eduardo Caio Torres-Santos, Claudia Masini d’Avila-Levy
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The Trypanosomatidae family encompasses unicellular flagellates and obligate parasites of invertebrates, vertebrates, and plants. Trypanosomatids are traditionally divided into heteroxenous, characterized by the alternation of the life cycle between
Externí odkaz:
https://doaj.org/article/664bb832f400494d86499d2dfe4b8162
Autor:
Vítor Ennes-Vidal, André Nóbrega Pitaluga, Constança Felícia De Paoli de Carvalho Britto, Marta Helena Branquinha, André Luis Souza dos Santos, Rubem Figueiredo Sadok Menna-Barreto, Claudia Masini d’Avila-Levy
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
BACKGROUND Calpains are present in almost all organisms and comprise a family of calcium-dependent cysteine peptidases implicated in crucial cellular functions. Trypanosoma cruzi, the causative agent of Chagas disease, presents an expansion on this g
Externí odkaz:
https://doaj.org/article/4a133f0bd9f9428a808dacbbf1ca4af9
Autor:
Carolina Boucinha, Amanda R Caetano, Helena LC Santos, Raphael Helaers, Miikka Vikkula, Marta Helena Branquinha, André Luis Souza dos Santos, Philippe Grellier, Karina Alessandra Morelli, Claudia Masini d‘Avila-Levy
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
BACKGROUND Biodiversity screens and phylogenetic studies are dependent on reliable DNA sequences in public databases. Biological collections possess vouchered specimens with a traceable history. Therefore, DNA sequencing of samples available at insti
Externí odkaz:
https://doaj.org/article/6f1d6151b5ff4382a27dbf05ea188866
Autor:
Vítor Ennes-Vidal, Marta Helena Branquinha, André Luis Souza dos Santos, Claudia Masini d’Avila-Levy
Publikováno v:
Cells, Vol 10, Iss 2, p 299 (2021)
Calpains are calcium-dependent cysteine peptidases that were originally described in mammals and, thereafter, their homologues were identified in almost all known living organisms. The deregulated activity of these peptidases is associated with sever
Externí odkaz:
https://doaj.org/article/51075bdd7fb140898507169b5da94350
Autor:
Carolina Valença Barbosa, Magali Muniz Barreto, Rosemary de Jesus Andrade, Fernando Sodré, Claudia Masini d'Avila-Levy, José Mauro Peralta, Ricardo Pereira Igreja, Heloisa Werneck de Macedo, Helena Lucia Carneiro Santos
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193860 (2018)
Intestinal parasitic infections are considered a serious public health problem and widely distributed worldwide, mainly in urban and rural environments of tropical and subtropical countries. Globally, soil-transmitted helminths and protozoa are the m
Externí odkaz:
https://doaj.org/article/b982c119ceff46c9b3849b7124ae19b0
Autor:
Patrícia Mello Ferrão, Claudia Masini d'Avila-Levy, Tania Cremonini Araujo-Jorge, Wim Maurits Degrave, Antônio da Silva Gonçalves, Luciana Ribeiro Garzoni, Ana Paula Lima, Jean Jacques Feige, Sabine Bailly, Leila Mendonça-Lima, Mariana Caldas Waghabi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124832 (2015)
Several studies indicate that the activity of cruzipain, the main lysosomal cysteine peptidase of Trypanosoma cruzi, contributes to parasite infectivity. In addition, the parasitic invasion process of mammalian host cells is described to be dependent
Externí odkaz:
https://doaj.org/article/a0dea4a8a0bf4427b8806ac7e7237de7
Autor:
Fernanda de Aquino Marinho, Keyla Cristiny da Silva Gonçalves, Selma Soares de Oliveira, Ana-Carolina de Siqueira Couto de Oliveira, Maria Bellio, Claudia Masini d'Avila-Levy, André Luis Souza dos Santos, Marta Helena Branquinha
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 106, Iss 4, Pp 507-509 (2011)
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes. Miltefosine induced a process of programmed cell deat
Externí odkaz:
https://doaj.org/article/7ea7c6c2b000485ea86bf96039562185
Autor:
Lívia Almeida Uehara, Otacílio C Moreira, Ana Carolina Oliveira, Patrícia Azambuja, Ana Paula Cabral Araujo Lima, Constança Britto, André Luis Souza dos Santos, Marta Helena Branquinha, Claudia Masini d'Avila-Levy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1958 (2012)
BACKGROUND:Trypanosoma cruzi is the etiological agent of Chagas' disease. Cysteine peptidases are relevant to several aspects of the T. cruzi life cycle and are implicated in parasite-mammalian host relationships. However, little is known about the f
Externí odkaz:
https://doaj.org/article/bd3b1bd32fb649d6a199667b4ed5570a
Autor:
Erich Loza Telleria, Adriana Pereira Oliveira de Araújo, Nágila Francinete Secundino, Claudia Masini d'Avila-Levy, Yara Maria Traub-Csekö
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10697 (2010)
BACKGROUND: Midgut enzymatic activity is one of the obstacles that Leishmania must surpass to succeed in establishing infection. Trypsins are abundant digestive enzymes in most insects. We have previously described two trypsin cDNAs of L. longipalpis
Externí odkaz:
https://doaj.org/article/743f6e0d014f420a8f5ec1747b288b1b