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Autor:
Claudia Magalhães Calvet, Tatiana Araújo Silva, Diane Thomas, Brian Suzuki, Ken Hirata, Jair Lage Siqueira-Neto, James H McKerrow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008726 (2020)
Chagas' Disease, caused by the protozoan parasite Trypanosoma cruzi, is responsible for up to 41% of the heart failures in endemic areas in South America and is an emerging infection in regions of North America, Europe, and Asia. Treatment is subopti
Externí odkaz:
https://doaj.org/article/1df42a5db86d474e93c1b686655ce8fd
Autor:
Guilherme Curty Lechuga, Júlio Cesar Borges, Claudia Magalhães Calvet, Humberto Pinheiro de Araújo, Aline Araujo Zuma, Samara Braga do Nascimento, Maria Cristina Machado Motta, Alice Maria Rolim Bernardino, Mirian Claudia de Souza Pereira, Saulo Cabral Bourguignon
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 154-164 (2016)
Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that
Externí odkaz:
https://doaj.org/article/4a2648c0a17b48edabc8f84da8374811
Autor:
Claudia Magalhães Calvet, Tatiana Galvão Melo, Luciana Ribeiro Garzoni, Francisco Odencio Rodrigues Oliveira-Jr, Dayse Teixeira Silva Neto, Maria de Nazareth Silveira Leal Meirelles, Mirian Claudia De Souza Pereira
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits multiple strategies to ensure its establishment and persistence in the host. Although this parasite has the ability to infect different organs, heart impairment is the most frequent
Externí odkaz:
https://doaj.org/article/933540560cff4b8ba2c188af79f8051a
Autor:
Tatiana Araújo, Silva, Luis Felipe de Carvalho, Ferreira, Mirian Claudia de Souza, Pereira, Claudia Magalhães, Calvet
Publikováno v:
International Journal of Molecular Sciences
Transforming growth factor beta (TGF-β) is a determinant for inflammation and fibrosis in cardiac and skeletal muscle in Chagas disease. To determine its regulatory mechanisms, we investigated the response of Trypanosoma cruzi-infected cardiomyocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aec4c7be9ac7d40c581eabc9669efeff
https://pubmed.ncbi.nlm.nih.gov/31569452
https://pubmed.ncbi.nlm.nih.gov/31569452