Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claudia M. Wever"'
Autor:
Nathalie A. Johnson, Francois Mercier, Ida LaPorta, Alexandre Bazinet, Yoon Kow Young, Ryan N Rys, Amadou Barry, Alma Mendoza, Claudia M. Wever, Celia M. T. Greenwood
Publikováno v:
Leukemia & Lymphoma. 62:2352-2359
Diagnosis and minimal residual disease (MRD) monitoring of chronic lymphocytic leukemia (CLL) by flow cytometry currently requires multiple antibody panels. We added CD23 and CD200 to the EuroFlowT...
Autor:
Thomas B Duguet, Claude L Charvet, Sean G Forrester, Claudia M Wever, Joseph A Dent, Cedric Neveu, Robin N Beech
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004826 (2016)
Helminth parasites rely on fast-synaptic transmission in their neuromusculature to experience the outside world and respond to it. Acetylcholine plays a pivotal role in this and its receptors are targeted by a wide variety of both natural and synthet
Externí odkaz:
https://doaj.org/article/371b1798dcb24cd888a2df12fb70ba77
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138804 (2015)
New compounds are needed to treat parasitic nematode infections in humans, livestock and plants. Small molecule anthelmintics are the primary means of nematode parasite control in animals; however, widespread resistance to the currently available dru
Externí odkaz:
https://doaj.org/article/bb50b715a995452cb0d2ea91a313f5cb
Autor:
Christophe Goncalves, Annette M. Staiger, Ryan N Rys, David Scott, S. Frenkiel, Josée Hébert, Christian Steidl, Dominique Geoffrion, Claudia M Wever, Anthony Letai, Nathalie A. Johnson, Pierre Sesques, Artin Ghassemian, German Ott, Tina Petrogiannis-Haliotis, Jeremy Ryan, Koren K. Mann, Eugene Brailovski, Sonia V. del Rincón, Svetlana Dmitrienko, Liliana Stoica
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 1002, p 1002 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 1002, p 1002 (2021)
To determine causes of apoptotic resistance, we analyzed 124 primary B cell NHL samples using BH3 profiling, a technique that measures the mitochondrial permeabilization upon exposure to synthetic BH3 peptides. Our cohort included samples from chroni
Autor:
Claudia M Wever, Svetlana Dmitrienko, Christina Gavino, Dominique Geoffrion, Stephen Yu, Josée Hébert, Ryan D. Morin, Koren K. Mann, Donald C. Vinh, Maryse Lemaire, Tina Petrogiannis-Haliotis, Miguel Alcaide, Bruno M. Grande, Nathalie A. Johnson, Yasser Riazalhosseini
Publikováno v:
Leukemia & Lymphoma. 59:2159-2174
Relapse occurs in 10-40% of Burkitt lymphoma (BL) patients that have completed intensive chemotherapy regimens and is typically fatal. While treatment-naive BL has been characterized, the genomic landscape of BL at the time of relapse (rBL) has never
Autor:
François Mercier, Ida LaPorta, Christian Young, Alexandre Bazinet, Claudia M Wever, Celia M. T. Greenwood, Alma Mendoza, Ryan N Rys, Amadou Barry, Sylvain Gimmig, Nathalie A. Johnson
Publikováno v:
Blood. 134:5451-5451
Background: Chronic lymphocytic leukemia (CLL) has a classic immunophenotype, consisting of light chain restriction, CD5+, CD19+, dim CD20, CD23+, CD43+, CD200+, CD10- and CD79b-. This distinguishes it from normal B cells and other lymphoproliferativ
Autor:
Pierre Sesques, Dominique Geoffrion, Liliana Stoica, German Ott, Christian Steidl, Annette M. Staiger, Tina Petrogiannis-Haliotis, Anthony Letai, David W. Scott, Frenkiel Saul, Nathalie A. Johnson, Koren K. Mann, Claudia M Wever, Brailovski Eugene, Jeremy Ryan, Svetlana Dmitrienko, Josée Hébert, Ghassemian Artin
Publikováno v:
Blood. 132:4126-4126
Background: The anti-apoptotic protein BCL2 is expressed in most non-Hodgkin lymphomas (NHL) including chronic lymphocytic leukemias (CLL), mantle cell lymphomas (MCL), follicular lymphomas (FL), diffuse large B cell lymphomas (DLBCL) and marginal zo
Autor:
Claudia M Wever, Ryan D. Morin, Nathalie A. Johnson, Donald C. Vinh, Josée Hébert, Maryse Lemaire, Yasser Riazalhosseini
Publikováno v:
Cancer Research. 77:2447-2447
Background: Burkitt Lymphoma (BL) is characterized by rapid cellular proliferation driven by the canonical IG-MYC translocation. BL can evade apoptosis by silencing the tumor suppressor TP53 or by mutating MYC. Other mutations contribute to the patho
Autor:
Antoine G. Godin, Joseph A. Dent, Nela Durisic, Melike Lakadamyali, Claudia M Wever, Colin D. Heyes
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(37)
The subunit stoichiometry of heteromeric glycine-gated channels determines fundamental properties of these key inhibitory neurotransmitter receptors; however, the ratio of α1- to β-subunits per receptor remains controversial. We used single-molecul
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003586 (2013)
PLoS Pathogens
PLoS Pathogens
Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission. They are proven drug targets in nematodes and arthropods, but are poorly characterized in flatworms. In this study, we characterized the anion-selective, non-acetyl