Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Claudia M. Muller"'
Autor:
Richard L. Stiller, Annette Scierka, Jack R. Lancaster, David W. Watkins, Yong-Myeong Kim, Charles W. Buffington, Ryan D. Cook, Claudia M. Muller
Publikováno v:
Anesthesiology. 84:1435-1442
Background Animals subjected to immunostimulatory conditions (sepsis) exhibit decreased total cytochrome P450 content and decreased P450-dependent drug metabolism. Cytochrome P450 function is of clinical significance because it mediates the metabolis
Autor:
Hector A. Bergonia, Young-Myeong Kim, Jack R. Lancaster, W.David Watkins, Bruce R. Pitt, Claudia M. Muller
Publikováno v:
Journal of Biological Chemistry. 270:5710-5713
We report here that, like nonheme iron, protein-bound intracellular heme iron is also a target for destruction by endogenously produced nitric oxide (NO). In isolated rat hepatocytes NO synthesis results in substantial (approximately 60%) and compara
Publikováno v:
Anesthesia & Analgesia. 85:1180