Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claudia Loske"'
Autor:
Grant Stuchbury, James N. Burnell, Claudia Loske, Susana Garcia de Arriba, Gerald Münch, Jennifer Yarin
Publikováno v:
Neurobiology of Aging. 28:1044-1050
Advanced glycation end products (AGEs) are found in various intraneuronal protein deposits such as neurofibrillary tangles in Alzheimer's disease and Lewy bodies in Parkinson's disease. Among the many reactive carbonyl compounds and AGE precursors, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c9c612a160c2d10fe07e6f2ee1daa1
https://doi.org/10.1016/j.neurobiolaging.2006.05.007
https://doi.org/10.1016/j.neurobiolaging.2006.05.007
Autor:
Gerald Münch, Peter Riederer, Matthias Wycislo, A. Gerdemann, Dieter Palm, Claudia Loske, Reinhard Schinzel, Walter Schepl
Publikováno v:
European Journal of Biochemistry. 267:4171-4178
beta-Amyloid deposits, hallmarks of Alzheimer's disease, contain both sugar-derived 'advanced glycation end products' (AGEs) and copper and iron ions. Our in vitro experiments using synthetic beta-amyloid peptide and glucose or fructose show that for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b38f20cdefcf3fee6351fd7794e5b2a9
https://doi.org/10.1046/j.1432-1327.2000.01452.x
https://doi.org/10.1046/j.1432-1327.2000.01452.x
Autor:
Klaus Wessel, Claudia Loske, Reinhard Schinzel, Gerald Münch, Hans Tritschler, Gerd Fleischer, Ina Meiners, Susana Garcia de Arriba, Michael Lobisch
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 23(11)
Advanced glycation endproducts (AGEs) accumulate on long-lived proteins, including β-amyloid plaques in Alzheimer's disease, and are suggested to contribute to neuronal dysfunction and cell death. We have investigated the effects of a model AGE upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9121add598082eb0b0860f465b5573e
https://pubmed.ncbi.nlm.nih.gov/14600438
https://pubmed.ncbi.nlm.nih.gov/14600438
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 111(3)
Beta-amyloid peptide (Abeta) and "Advanced glycation endproducts" (AGEs) are components of the senile plaques in Alzheimer's disease patients. It has been proposed that both AGEs and Abeta exert many of their effects, which include the upregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48983d7967033149519bbc95415cc0d
https://pubmed.ncbi.nlm.nih.gov/14991463
https://pubmed.ncbi.nlm.nih.gov/14991463
Publikováno v:
Journal of Alzheimer's disease : JAD. 5(1)
Advanced glycation endproducts (AGEs), sugar-derived protein modifications and lipid peroxidation products are prominent features of Alzheimer's disease. AGEs accumulate on beta-amyloid plaques during the course of the disease and can exert chronic o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b7a2d8df25bb7ba605ce609e3d8ada
https://pubmed.ncbi.nlm.nih.gov/12590163
https://pubmed.ncbi.nlm.nih.gov/12590163
Publikováno v:
GBM Annual Fall meeting Halle 2002. 2002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7347c0e35097e603a64d9cbcf6b359e8
https://doi.org/10.1240/sav_gbm_2002_h_000147
https://doi.org/10.1240/sav_gbm_2002_h_000147
Publikováno v:
Zeitschrift fur Gerontologie und Geriatrie. 34(6)
Non-enzymatic glycation of proteins with reducing sugars and subsequent transition metal-catalyzed oxidations leads to the formation of protein-bound "advanced glycation endproducts" (AGEs). They accumulate on long-lived proteins including on and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ec75bd97e22feecf0ac052c9ecba53
https://pubmed.ncbi.nlm.nih.gov/11828884
https://pubmed.ncbi.nlm.nih.gov/11828884
Autor:
Reinhard Schinzel, Arne Neumann, Claudia Loske, Andreas Simm, Sherif Daoud, Claudius Diez, Daniela Fraccarollo
Publikováno v:
Molecular medicine (Cambridge, Mass.). 7(8)
BACKGROUND: Cardiovascular diseases are the leading cause of death in the Western world, especially in the elderly. Myocardial fibrosis induced by activated cardiac fibroblasts is thought to play a key role in the pathogenesis of cardiovascular disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86c262a17f2e4258390569dbec16eee
https://pubmed.ncbi.nlm.nih.gov/11591890
https://pubmed.ncbi.nlm.nih.gov/11591890
Autor:
Ralf Dringen, Peter Riederer, Winnie Deuther-Conrad, Gerald Münch, Reinhard Schinzel, Claudia Loske
Publikováno v:
Neuroscience letters. 312(1)
The reaction of proteins with reducing sugars leads to the formation of 'advanced glycation endproducts' (AGEs). They accumulate in Alzheimer's disease brain in the vicinity of beta-amyloid plaques. AGEs are cytotoxic by a mechanism involving reactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f63c33cb305602688450f31ba1ecebd
https://pubmed.ncbi.nlm.nih.gov/11578838
https://pubmed.ncbi.nlm.nih.gov/11578838