Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Claudia Lenzner"'
Publikováno v:
European Journal of Biochemistry. 257:62-68
We have isolated genomic recombinants containing the complete gene coding for the rabbit translationally controlled tumor protein (TCTP), also known as histamine-releasing factor (HRF) P23. The gene is organized into five introns and six exons and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc92f10194fb19802c17a6172ee4df7
https://doi.org/10.1046/j.1432-1327.1998.2570062.x
https://doi.org/10.1046/j.1432-1327.1998.2570062.x
Publikováno v:
Blood. 89:1793-1799
We investigated the DNA of 29 unrelated pyruvate kinase (PK) deficiency (PKD) patients from Central Europe with hereditary nonspherocytic hemolytic anemia for mutations in the PK-L/R gene. Among 58 potentially affected alleles, 53 mutations were iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2e781fa0952b6622c32371e0bf6f02
https://doi.org/10.1182/blood.v89.5.1793.1793_1793_1799
https://doi.org/10.1182/blood.v89.5.1793.1793_1793_1799
Publikováno v:
DNA Sequence. 8:45-53
The human pyruvate kinase L/R-gene has been completely sequenced in unrelated normal individuals and in pyruvate kinase-deficient patients by a PCR-based direct genomic sequencing approach and analyzed for polymorphisms. The total length of the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd361c97e7283869459cd400a219fc8
https://doi.org/10.3109/10425179709020884
https://doi.org/10.3109/10425179709020884
Autor:
Eike Fuhrmann, H. Pöche, Gundula Thiel, Tanka Losanova, Peter Nürnberg, Ingrid Barth, Christian Peters, Claudia Lenzner
Publikováno v:
Electrophoresis. 12:186-192
Germline and somatic instability of the human genome was studied, using synthetic oligonucleotides specific for simple repeat motifs. The following probes were used: (GTG)5, (GACA)4, (GATA)4, (CT)8, (TTAGGG)3, (GT)8, (GAA)6 and (GGAT)4. Each of them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00674137430f74bc07383b8bf74c76b
https://doi.org/10.1002/elps.1150120215
https://doi.org/10.1002/elps.1150120215
Autor:
Sebastian Beck Jørgensen, Emmanuel Gomas, Claudia Lenzner, Axel Kahn, Benoit Viollet, Morris J. Birnbaum, Christophe Perrin, Erik A. Richter, Alain Géloën, Daisy Flamez, Gaël Nicolas, Fabrizio Andreelli, Rémy Burcelin, David Carling, Sophie Vaulont, James Mu, Olivier Baud, Myriam Bennoun, Frans Schuit, Jørgen F. P. Wojtaszewski
AMP-activated protein kinase (AMPK) is viewed as a fuel sensor for glucose and lipid metabolism. To better understand the physiological role of AMPK, we generated a knockout mouse model in which the AMPKalpha2 catalytic subunit gene was inactivated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aade9677aa4483676bf5c9037ee2cc1
https://europepmc.org/articles/PMC151837/
https://europepmc.org/articles/PMC151837/
Autor:
Claudia Lenzner, Alfred Neubauer
Publikováno v:
De Diversis Artibus ISBN: 9782503508887
Fundamental Changes in Cellular Biology in the 20th Century. Biology of Development, Chemistry and Physics in the Life Sciences: Proceedings of the XXth International Congress of History of Science (Liège, 20-26 July 1997) Vol. III
Fundamental Changes in Cellular Biology in the 20th Century. Biology of Development, Chemistry and Physics in the Life Sciences: Proceedings of the XXth International Congress of History of Science (Liège, 20-26 July 1997) Vol. III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be4f756244a53a494cb3cb211166b21
https://doi.org/10.1484/m.dda-eb.4.00566
https://doi.org/10.1484/m.dda-eb.4.00566
Autor:
Vaclav Brabec, Adriena Sakalova, André Reis, Claudia Lenzner, Bernd-Joachim Thiele, Peter Nürnberg, Gisela Jacobasch
Publikováno v:
Blood. 83(10)
We have completely sequenced the introns of the human L-type pyruvate kinase (PK) gene using the published cDNA sequence. Subsequently, DNA from 12 unrelated PK deficiency (PKD) patients of Central European origin was investigated for mutations in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a5ee90f8fc23793cd422b114f89718
https://pubmed.ncbi.nlm.nih.gov/8180378
https://pubmed.ncbi.nlm.nih.gov/8180378
Autor:
Yves Le Bouc, Sophie Vaulont, Randa Zaoui, Martin Holzenberger, Ghislaine Hamard, Claudia Lenzner, Patricia Leneuve
Publikováno v:
Nucleic Acids Research. 28:92e-92
Conditional gene targeting uses the insertion of expression cassettes for the selection of targeted embryonic stem cells. The presence of these cassettes in the final targeted chromosomal locus may affect the normal expression of the targeted gene an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0921c04df740ea0629fd643e6d3e3f
https://doi.org/10.1093/nar/28.21.e92
https://doi.org/10.1093/nar/28.21.e92
Publikováno v:
Human Molecular Genetics. 3:523-523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbc6202bf9fdece527ac6d9c16959a9
https://doi.org/10.1093/hmg/3.3.523-a
https://doi.org/10.1093/hmg/3.3.523-a
Autor:
Claudia Lenzner, Benoit Viollet, Sophie Vaulont, Laurence Gourdon, Isabelle Leclerc, Axel Kahn
Publikováno v:
Scopus-Elsevier
Mutations in the HNF4alpha gene are responsible for type 1 maturity-onset diabetes of the young (MODY1), which is characterized by a defect in insulin secretion. Hepatocyte nuclear factor (HNF)-4alpha is a transcription factor that plays a critical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f9cb81a66ad3cdb8af91a6986452c2
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035406121&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035406121&partnerID=MN8TOARS