Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Claudia Kragl"'
Autor:
Markus Schrettl, Elaine Bignell, Claudia Kragl, Yasmin Sabiha, Omar Loss, Martin Eisendle, Anja Wallner, Herbert N Arst, Ken Haynes, Hubertus Haas
Publikováno v:
PLoS Pathogens, Vol 3, Iss 9, Pp 1195-1207 (2007)
Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen. We have previously demonstrated that
Externí odkaz:
https://doaj.org/article/bba175b549eb4c239cf95aa34c11cc84
Autor:
Hyojeong Yi, Thorsten Heinekamp, Ernst R. Werner, Paul Illmer, Ilse D. Jacobsen, William C. Nierman, Claudia Kragl, Martin Eisendle, Axel A. Brakhage, H. Stanley Kim, Markus Schrettl, Hubertus Haas
Publikováno v:
Molecular Microbiology. 70:27-43
Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two high-affinity iron uptake systems: iron uptake mediated by the extracellular siderophore triacetylfusarinine C and reductive iron assimilation. Furthermore, A. fum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba5f838e314cee968bb305033e6e38e4
https://doi.org/10.1111/j.1365-2958.2008.06376.x
https://doi.org/10.1111/j.1365-2958.2008.06376.x
Autor:
Elaine Bignell, Herbert N. Arst, Ken Haynes, Thomas R. Rogers, Hubertus Haas, Claudia Kragl, Markus Schrettl, Chistoph Joechl
Publikováno v:
The Journal of Experimental Medicine
The ability to acquire iron in vivo is essential for most microbial pathogens. Here we show that Aspergillus fumigatus does not have specific mechanisms for the utilization of host iron sources. However, it does have functional siderophore-assisted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa73178e7f172b8f497167212331a6f
https://doi.org/10.1084/jem.20041242
https://doi.org/10.1084/jem.20041242
Publikováno v:
Eukaryotic cell. 6(8)
Aspergillus fumigatus excretes the fusarinine-type siderophore desferri-triacetylfusarinine C (DF-TafC) to mobilize iron. DF-TafC is a cyclic peptide consisting of three N 5 - cis -anhydromevalonyl- N 5 -hydroxy- N 2 -acetyl- l -ornithine residues li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6a23aaab000c120095c8f38e9ef0b4
https://pubmed.ncbi.nlm.nih.gov/17586718
https://pubmed.ncbi.nlm.nih.gov/17586718
Autor:
Claudia Kragl, Herbert N. Arst, Markus Schrettl, Omar Loss, Hubertus Haas, Anja Wallner, Yasmin Sabiha, Ken Haynes, Elaine Bignell, Martin Eisendle
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 3, Iss 9, Pp 1195-1207 (2007)
PLoS Pathogens, Vol 3, Iss 9, Pp 1195-1207 (2007)
Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen. We have previously demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f434b19a0ed2ca71852ddb64a53bf4ec
https://pubmed.ncbi.nlm.nih.gov/17845073
https://pubmed.ncbi.nlm.nih.gov/17845073
Iron is required by most organisms, but an excess of this metal is potentially toxic. Consequently, uptake and intracellular storage of iron are tightly controlled. The filamentous fungus A. nidulans lacks the iron storage compound ferritin but posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2b1848a8c2e015f530f95e64890803
https://europepmc.org/articles/PMC1595343/
https://europepmc.org/articles/PMC1595343/
