Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claudia Kettlun, Leyton"'
Autor:
Nahum Puebla-Osorio, Natalie Wall Fowlkes, Hampartsoum B. Barsoumian, Kristina Xega, Gitika Srivastava, Claudia Kettlun-Leyton, Sara Nizzero, Tiffany Voss, Thomas S. Riad, Christina Wong, Ailing Huang, Yun Hu, Joylise Mitchell, Mingee Kim, Zahid Rafiq, Kewen He, Duygu Sezen, Ethan Hsu, Fatemeh Masrorpour, Aurian Maleki, Carola Leuschner, Maria Angelica Cortez, Philipp Oertle, Marko Loparic, Marija Plodinec, Janet L. Markman, James W. Welsh
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionEffective infiltration of chimeric antigen receptor T (CAR-T) cells into solid tumors is critical for achieving a robust antitumor response and improving therapeutic outcomes. While CAR-T cell therapies have succeeded in hematologic malig
Externí odkaz:
https://doaj.org/article/e15d8e28463245d5a2e2e3d70c939f5b
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A. Mitchell, Tiffany A. Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background While improvements in immunoradiotherapy have significantly improved outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanisms of r
Externí odkaz:
https://doaj.org/article/a090d791bef0465c93bf5eb25e2451f7
Autor:
James Welsh, Sébastien Paris, Hampartsoum Barsoumian, Yun Hu, Mark Wasley, Liangpeng Yang, Quynh-Nhu Nguyen, Fatemeh Masrorpour, Saumil Gandhi, Genevieve Bertolet, Lily Schuda, Kewen He, Duygu Sezen, Joylise Mitchell, Tiffany Voss, SILVA Jordan, Claudia Kettlun Leyton, Nahum Puebla-Osorio, Angelica Cortez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ac4c8f454ce64995a234fdcb51a58ba6
Autor:
Yun Hu, Sebastien Paris, Narayan Sahoo, Genevieve Bertolet, Qi Wang, Qianxia Wang, Hampartsoum Barsoumian, Jordan SILVA, Ailing Huang, Claudia Kettlun Leyton, Tiffany Voss, Ethan Hsu, Fatemeh Masrorpour, Carola Leuschner, Nahum Puebla Osorio, Quynh Nguyen, Saumil Gandhi, Jing Wang, Maria Cortez, James Welsh
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f5a1b7995399d8888bc64c763d5326
https://doi.org/10.1136/jitc-2022-sitc2022.0869
https://doi.org/10.1136/jitc-2022-sitc2022.0869
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A Mitchell, Tiffany A Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Background: While improvements in radioimmunotherapy have made significant headway in improving outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d809078015ea6207acaa12126d68a804
https://doi.org/10.21203/rs.3.rs-1627514/v1
https://doi.org/10.21203/rs.3.rs-1627514/v1
Autor:
Kewen He, L. Yang, Yun Hu, Saumil Gandhi, Nahum Puebla-Osorio, Angelica Cortez, Duygu Sezen, Genevieve Bertolet, Claudia Kettlun Leyton, Lily Schuda, Sébastien Paris, Hampartsoum B. Barsoumian, Silva Jordan, Tiffany Voss, Fatemeh Masrorpour, Mark Wasley, Joylise Mitchell, James W. Welsh, Quynh-Nhu Nguyen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTIGIT and LAG3 are inhibitory receptors expressed on cytotoxic CD8+ T cells and NK cells and directly inhibit the activation and proliferation of these cells. We proposed that blockade of TIGIT and LAG3 could improve antitumor immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ce40af4bdeb20a51964f1cb4c00737
https://doi.org/10.1136/jitc-2021-sitc2021.575
https://doi.org/10.1136/jitc-2021-sitc2021.575
Autor:
Mansi D. Amin, M. John Hicks, Malgorzata Borowiak, Yiling Lu, Karl-Dimiter Bissig, Xavier Legras, Robia G. Pautler, Pavel Sumazin, Yung-Hsin Huang, Harshavardhan Doddapaneni, D. Williams Parsons, Barry Zorman, Masand M. Prakash, Yan Shi, Diane Yang, Oliver A. Hampton, Jianhong Hu, Donna M. Muzny, John A. Goss, Milton J. Finegold, Sanjeev A. Vasudevan, Gordon B. Mills, Dolores Lopez-Terrada, Mercedes Barzi, Leon Chen, Beatrice Bissig-Choisat, Patrick A. Thompson, M. Waleed Gaber, Claudia Kettlun-Leyton
Publikováno v:
Journal of Hepatology. 65:325-333
Background & Aims Pediatric liver cancer is a rare but serious disease whose incidence is rising, and for which the therapeutic options are limited. Development of more targeted, less toxic therapies is hindered by the lack of an experimental animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d968e8e8fb2452bd1b6c4cf93f3c922c
https://doi.org/10.1016/j.jhep.2016.04.009
https://doi.org/10.1016/j.jhep.2016.04.009
Autor:
Roman A. Sukhovershin, Colleen Stubbs, Brandon K. Walther, Anahita Mojiri, Hongye Li, Rhonda Holgate, Claudia Kettlun-Leyton, Dan Kiss, Tulsi Ram Damase, John P. Cooke, Yi Liang, Palas K. Chanda, Celetta Callaway
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77fa1a5715482e75cd4494fba4e7973b
https://doi.org/10.1096/fasebj.2020.34.s1.00429
https://doi.org/10.1096/fasebj.2020.34.s1.00429
Autor:
James M. Wilson, Ryan Himes, Xavier Legras, Peter Bell, Robert L. Kruse, Pradip K. Saha, Lili Wang, Karl-Dimiter Bissig, Hon-Chiu Eastwood Leung, Claudia Kettlun Leyton, William R. Lagor, Matthew C. Hill, Francis P. Pankowicz, Mercedes Barzi, Leon Chen, Beatrice Bissig-Choisat, John A. Goss, Lawrence Chan
Publikováno v:
Nature communications. 6
Diseases of lipid metabolism are a major cause of human morbidity, but no animal model entirely recapitulates human lipoprotein metabolism. Here we develop a xenograft mouse model using hepatocytes from a patient with familial hypercholesterolaemia c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c2031889ba1b29130366b263661407
https://pubmed.ncbi.nlm.nih.gov/26149614
https://pubmed.ncbi.nlm.nih.gov/26149614
Autor:
Hu, Yun1 (AUTHOR), Paris, Sébastien2 (AUTHOR), Bertolet, Genevieve1 (AUTHOR), Barsoumian, Hampartsoum B.1 (AUTHOR), He, Kewen1,3 (AUTHOR), Sezen, Duygu1,4 (AUTHOR), Chen, Dawei1,3 (AUTHOR), Wasley, Mark1 (AUTHOR), SILVA, Jordan DA2 (AUTHOR), Mitchell, Joylise A.1 (AUTHOR), Voss, Tiffany A.1 (AUTHOR), Masrorpour, Fatemeh1 (AUTHOR), Leyton, Claudia Kettlun1 (AUTHOR), Yang, Liangpeng1 (AUTHOR), Leuschner, Carola1 (AUTHOR), Puebla-Osorio, Nahum1 (AUTHOR), Gandhi, Saumil1 (AUTHOR), Nguyen, Quynh-Nhu1 (AUTHOR), Cortez, Maria Angelica1 (AUTHOR), Welsh, James W.1 (AUTHOR) jwelsh@mdanderson.org
Publikováno v:
Journal of Nanobiotechnology. 9/19/2022, Vol. 20 Issue 1, p1-19. 19p.