Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Claudia Kappen"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Maternal diabetes during pregnancy is well known to be associated with a higher risk for structural birth defects in the offspring. Recent searches for underlying mechanisms have largely focused on aberrant processes in the embryo itsel
Externí odkaz:
https://doaj.org/article/590f5b01b7f4419f9f16556222d82597
Autor:
Stephania A. Cormier, Claudia Kappen
Publikováno v:
Journal of Developmental Biology, Vol 12, Iss 1, p 5 (2024)
Hox genes encode transcription factors whose roles in patterning animal body plans during embryonic development are well-documented. Multiple studies demonstrate that Hox genes continue to act in adult cells, in normal differentiation, in regenerativ
Externí odkaz:
https://doaj.org/article/e95f36d4837848459384957b54206a31
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart defects. Progeny from affected pregnancies are also predisposed to developing cardiometabolic dise
Externí odkaz:
https://doaj.org/article/666212fe88914dafa1cc7036ee14d135
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development in the mouse. While CRISPR-based gene editing of multiple genes at once offers an a
Externí odkaz:
https://doaj.org/article/9f43982f7b4148708a7c6068b9cecbb6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Maternal diabetes in early pregnancy increases the risk for birth defects in the offspring, particularly heart, and neural tube defects. While elevated glucose levels are characteristic for diabetic pregnancies, these are also accompanied by hyperlip
Externí odkaz:
https://doaj.org/article/b703372211204f71a054d78b4361c89e
Autor:
J. Michael Salbaum, Claudia Kruger, Jacalyn MacGowan, Nils J. Herion, David Burk, Claudia Kappen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/11f46a7df45149dcb9181e54fa1c9dbf
Publikováno v:
Genomics Data, Vol 12, Iss C, Pp 24-27 (2017)
Externí odkaz:
https://doaj.org/article/6757082479ad443d9aa476344182aaf8
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224754 (2019)
Diabetes in the mother during pregnancy is a risk factor for birth defects and perinatal complications and can affect long-term health of the offspring through developmental programming of susceptibility to metabolic disease. We previously showed tha
Externí odkaz:
https://doaj.org/article/00f2a0f4f8b34d3e9b02a36109533a5f
Autor:
Claudia Kappen
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146019 (2016)
The process of patterning along the anterior-posterior axis in vertebrates is highly conserved. The function of Hox genes in the axis patterning process is particularly well documented for bone development in the vertebral column and the limbs. We he
Externí odkaz:
https://doaj.org/article/24704909a463494b8e596e5021b450fd
Autor:
Rodrigo Gularte-Mérida, Lisa M DiCarlo, Ginger Robertson, Jacob Simon, William D Johnson, Claudia Kappen, Juan F Medrano, Brenda K Richards
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110424 (2014)
The specific genes regulating the quantitative variation in macronutrient preference and food intake are virtually unknown. We fine mapped a previously identified mouse chromosome 17 region harboring quantitative trait loci (QTL) with large effects o
Externí odkaz:
https://doaj.org/article/7e6174250cb34a3cbd44d2d192275b85