Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Claudia Kühne"'
Autor:
Nina Dedic, Claudia Kühne, Karina S. Gomes, Jakob Hartmann, Kerry J. Ressler, Mathias V. Schmidt, Jan M. Deussing
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Dysregulation of the corticotropin-releasing hormone (CRH) system has been implicated in stress-related psychopathologies such as depression and anxiety. Although most studies have linked CRH/CRH receptor 1 signaling to aversive, stress-like behavior
Externí odkaz:
https://doaj.org/article/d997b72259724e658687c6540d4c1c3c
Autor:
Androniki Raftogianni, Lena C. Roth, Diego García-González, Thorsten Bus, Claudia Kühne, Hannah Monyer, Daniel J. Spergel, Jan M. Deussing, Valery Grinevich
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors play a leading role in the inhibition of the hypothalamic–pituitary–gonadal (HPG) axis during acute stress. To further study the effects of CRH receptor sig
Externí odkaz:
https://doaj.org/article/b727de6836224235bd7a4cdb92e8ffbc
Autor:
Ludwig Czibere, Laura A Baur, Anke Wittmann, Katja Gemmeke, Andrea Steiner, Peter Weber, Benno Pütz, Nafees Ahmad, Mirjam Bunck, Cornelia Graf, Regina Widner, Claudia Kühne, Markus Panhuysen, Boris Hambsch, Gabriele Rieder, Thomas Reinheckel, Christoph Peters, Florian Holsboer, Rainer Landgraf, Jan M Deussing
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23604 (2011)
Behavioral endophenotypes are determined by a multitude of counteracting but precisely balanced molecular and physiological mechanisms. In this study, we aim to identify potential novel molecular targets that contribute to the multigenic trait "anxie
Externí odkaz:
https://doaj.org/article/5a2ad2e33cd54f34a13d737be0d182ea
Autor:
Claudia Kühne, Osborne F. X. Almeida, Nils C. Gassen, Elmira Anderzhanova, Ioannis Sotiropoulos, Chrysoula Dioli, Anna Pissioti, Mazen R. Harb, Alexandre V. Patchev, C. Catania, Este Leidmaa, Rainer Stoffel, Shuang Yu, Mary Gazea, Susanne Moosecker
Publikováno v:
Neuroscience. 479:91-106
Like other members of the superfamily of nuclear receptors, the peroxisome proliferator-activated receptor γ (PPARγ), is a ligand-activated transcription factor known for its insulin-sensitizing actions in the periphery. Despite only sparse evidenc
Autor:
Zoe Friedmann, Hans-Tilmann Kinkel, Claudia Kühner, Andreas Zsolnai, Annette Binder, Inge Mick
Publikováno v:
Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Supervised injectable opioid treatment (SIOT) is a promising alternative for people living with opioid use disorder (OUD) who have not sufficiently benefitted from oral opioid substitution treatment. Yet, SIOT utilization remains
Externí odkaz:
https://doaj.org/article/47846a7676cd4ba293c757c3769d3a5f
Autor:
Laura M. Fiori, Rixing Lin, Maria Holzapfel, Carola Eggert, Claudia Kühne, El Chérif Ibrahim, Rosa Eva Huettl, Gustavo Turecki, Juan Pablo Lopez, Naguib Mechawar, Alon Chen, Catherine Belzung, Aron Kos, Jean-François Théroux
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2020, ⟨10.1038/s41380-020-00953-7⟩
Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-00953-7⟩
Molecular Psychiatry, Nature Publishing Group, 2020, ⟨10.1038/s41380-020-00953-7⟩
Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-00953-7⟩
International audience; Major depressive disorder (MDD) is a complex and debilitating illness whose etiology remains unclear. Small RNA molecules, such as micro RNAs (miRNAs) have been implicated in MDD, where they display differential expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872b573747d2e7086eef60d6663f12d2
https://hal.archives-ouvertes.fr/hal-03019942/document
https://hal.archives-ouvertes.fr/hal-03019942/document
Autor:
Zoe Friedmann, Hans-Tilmann Kinkel, Claudia Kühner, Andreas Zsolnai, Inge Mick, Annette Binder
Publikováno v:
Harm Reduction Journal, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Injectable opioid agonist treatment (iOAT) is an effective option to support people living with opioid use disorder (OUD) who have not sufficiently benefitted from oral OAT. However, iOAT has been criticised based on theoretical a
Externí odkaz:
https://doaj.org/article/7a1e42a3ea2f45dfab686ab7763cdcac
Autor:
Katy Staikin, Meira Weiss, Jan M. Deussing, Alon Chen, Claudia Kühne, Julien Dine, Ofra Golani, Yael Kuperman, Matthias Eder, Assaf Ramot, Alon Harmelin, Wolfgang Wurst, Yair Shemesh, Tali Nahum
Publikováno v:
Cell Metabolism
CELL METABOLISM
Cell Metab. 23, 1185-1199 (2016)
CELL METABOLISM
Cell Metab. 23, 1185-1199 (2016)
Summary Signaling by the corticotropin-releasing factor receptor type 1 (CRFR1) plays an important role in mediating the autonomic response to stressful challenges. Multiple hypothalamic nuclei regulate sympathetic outflow. Although CRFR1 is highly e
Autor:
Jan M. Deussing, Claudia Kühne, Daniel J. Spergel, Diego García-González, Androniki Raftogianni, Lena C. Roth, Thorsten Bus, Valery Grinevich, Hannah Monyer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
FRONTIERS IN MOLECULAR NEUROSCIENCE
Frontiers in Molecular Neuroscience
FRONTIERS IN MOLECULAR NEUROSCIENCE
Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors play a leading role in the inhibition of the hypothalamic-pituitary-gonadal (HPG) axis during acute stress. To further study the effects of CRH receptor signali
Autor:
Elmira Anderzhanova, Julien Dine, Carsten T. Wotjak, Wolfgang Wurst, Annette M. Vogl, Mathias V. Schmidt, Jakob Hartmann, Bianca Schmid, Rafael Carvalho Almada, Valery Grinevich, Damian Refojo, Max L. Pöhlmann, Nina Dedic, Kerry J. Ressler, Simon Chang, Andreas Genewsky, Karina S. Gomes, Jan M. Deussing, Adam Kolarz, Alon Chen, Claudia Kühne, Michael W. Metzger, Mira Jakovcevski
Publikováno v:
Nature reviews / Neuroscience 21(6), 803-807 (2018). doi:10.1038/s41593-018-0151-z
Nat. Neurosci. 21, 803-807 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nat. Neurosci. 21, 803-807 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The interplay between corticotropin-releasing hormone (CRH) and the dopaminergic system has predominantly been studied in addiction and reward, while CRH-dopamine interactions in anxiety are scarcely understood. We describe a new population of CRH-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cb6fb9c8125c204ce1bd4e894f0617