Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Claudia Hagedorn"'
Autor:
Jonghui Kim, Karla Hegener, Claudia Hagedorn, Daniel Weidinger, Kashin Jamal Jameel, Inga Marte Charlott Seuthe, Sabine Eichhorn, Florian Kreppel, Jonas Jae-Hyun Park, Jürgen Knobloch
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to establish a robust method for the isolation and culture of epithelial cells from nasal polyps t
Externí odkaz:
https://doaj.org/article/304e50a68646407c9b03f07179f367f4
Autor:
Denice Weklak, Julian Tisborn, Maurin Helen Mangold, Raphael Scheu, Harald Wodrich, Claudia Hagedorn, Franziska Jönsson, Florian Kreppel
Publikováno v:
Viruses, Vol 15, Iss 11, p 2155 (2023)
To contain the spread of the SARS-CoV-2 pandemic, rapid development of vaccines was required in 2020. Rational design, international efforts, and a lot of hard work yielded the market approval of novel SARS-CoV-2 vaccines based on diverse platforms s
Externí odkaz:
https://doaj.org/article/9c051fa9814f47df9a98f77b9268f7b5
Autor:
Jonas Scholz, Patrick Philipp Weil, Daniel Pembaur, Georgia Koukou, Malik Aydin, Dorota Hauert, Jan Postberg, Florian Kreppel, Claudia Hagedorn
Publikováno v:
Viruses, Vol 14, Iss 9, p 1952 (2022)
Only two decades after discovering miRNAs, our understanding of the functional effects of deregulated miRNAs in the development of diseases, particularly cancer, has been rapidly evolving. These observations and functional studies provide the basis f
Externí odkaz:
https://doaj.org/article/af850ea691694d4a9e4877f85123e3d1
Autor:
Kingsley Gideon Kumashie, Marcin Cebula, Claudia Hagedorn, Florian Kreppel, Marina C. Pils, Friedrich Koch-Nolte, Björn Rissiek, Dagmar Wirth
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Chronic hepatotropic viral infections are characterized by exhausted CD8+ T cells in the presence of cognate antigen in the liver. The impairment of T cell response limits the control of chronic hepatotropic viruses. Immune-modulatory strategies are
Externí odkaz:
https://doaj.org/article/0ed1772624a74cefa35f6a86e82ebbd3
Autor:
Raphael L. Tsoukas, Wolfram Volkwein, Jian Gao, Maren Schiwon, Nora Bahlmann, Thomas Dittmar, Claudia Hagedorn, Eric Ehrke-Schulz, Wenli Zhang, Armin Baiker, Anja Ehrhardt
Publikováno v:
Cells, Vol 11, Iss 5, p 841 (2022)
To develop adenoviral cell- or tissue-specific gene delivery, understanding of the infection mechanisms of adenoviruses is crucial. Several adenoviral attachment proteins such as CD46, CAR and sialic acid have been identified and studied. However, mo
Externí odkaz:
https://doaj.org/article/077013b8e3424060bf933ba3d702382d
Autor:
Claudia Hagedorn, Johannes König
Publikováno v:
Nuclear Physics B, Vol 953, Iss , Pp - (2020)
We construct a supersymmetric model for leptons and quarks with the flavor symmetry Δ(384) and CP. The peculiar features of lepton and quark mixing are accomplished by the stepwise breaking of the flavor and CP symmetry. The correct description of l
Externí odkaz:
https://doaj.org/article/7c08dc7fb13f4b29a95bf7220753e949
Publikováno v:
Journal of High Energy Physics, Vol 2018, Iss 11, Pp 1-43 (2018)
Abstract We study a simple extension of the Standard Model that accounts for neutrino masses and dark matter. The Standard Model is augmented by two Higgs doublets and one Dirac singlet fermion, all charged under a new dark global symmetry. It is a g
Externí odkaz:
https://doaj.org/article/393dd798eaa14dac9a52e9a41aada30e
Publikováno v:
Physics Letters B, Vol 782, Iss , Pp 387-394 (2018)
We study the effect of lepton number violation (LNV) on baryon asymmetry, generated in the early Universe, in the presence of a dark sector with a global symmetry U(1)X, featuring asymmetric dark matter (ADM). We show that in general LNV, observable
Externí odkaz:
https://doaj.org/article/41c1a7d1b7ec407cbaefad96d0c9a6a4
Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions
Autor:
Denice Weklak, Daniel Pembaur, Georgia Koukou, Franziska Jönsson, Claudia Hagedorn, Florian Kreppel
Publikováno v:
Viruses, Vol 13, Iss 7, p 1300 (2021)
Adenovirus-based vectors are playing an important role as efficacious genetic vaccines to fight the current COVID-19 pandemic. Furthermore, they have an enormous potential as oncolytic vectors for virotherapy and as vectors for classic gene therapy.
Externí odkaz:
https://doaj.org/article/33dc0766eb09496486b71b678e971f66
Autor:
Claudia Hagedorn, Emiliano Molinaro
Publikováno v:
Nuclear Physics B, Vol 919, Iss C, Pp 404-469 (2017)
We perform a comprehensive analysis of the phenomenology of leptonic low and high energy CP phases in a scenario with three heavy right-handed neutrinos in which a flavor and a CP symmetry are non-trivially broken. All CP phases as well as lepton mix
Externí odkaz:
https://doaj.org/article/10facf3acd454a08a691979f30932de3