Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claudia Gosele"'
Autor:
František Liška, Claudia Gosele, Elena Popova, Blanka Chylíková, Drahomíra Křenová, Vladimír Křen, Michael Bader, Laura L Tres, Norbert Hubner, Abraham L Kierszenbaum
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60859 (2013)
Rat hypodactyly (hd) mutation is characterized by abnormal spermatogenesis and sperm decapitation, limb malformation (missing digits II and III) and growth retardation. We have previously reported centrobin (centrosome BRCA2-interacting protein) trun
Externí odkaz:
https://doaj.org/article/cf160853ad59418fb8fd678c28c51fb4
Autor:
Stephanie Krämer, Monika Reißmann, Boris Jerchow, Astrid Puppe, Kristina Ullmann, Thomas Rülicke, Elena Noe, Claudia Gosele, Anne Zintzsch, Hannah T. Nickles, Reinhart Kluge
Publikováno v:
Laboratory Animals. 51:573-582
Genetic alterations can unpredictably compromise the wellbeing of animals. Thus, more or less harmful phenotypes might appear in the animals used in research projects even when they are not subjected to experimental treatments. The severity classific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df505b73770bc6e3fd10b8e54a26553a
https://doi.org/10.1177/0023677217718863
https://doi.org/10.1177/0023677217718863
Autor:
Herbert Schulz, Bruce D. Hammock, Martin Vingron, Friedrich C. Luft, Volkmar Gross, Giannino Patone, Wolf-Hagen Schunck, Klaus Lindpaintner, Robert Fischer, Cosima Schmidt, Matthias Heinig, Oliver Hummel, Steven M. Weldon, Claudia Gosele, Judith Fischer, Svetlana Paskas, Henrike Maatz, Kathrin Saar, Norbert Hubner, Arnd Heuser, Stuart A. Cook, Jan Monti, Klaus Rohde, Rainer Dietz, Alexander Schirdewan
Publikováno v:
Nat Genet
We aimed to identify genetic variants associated with heart failure by using a rat model of the human disease. We performed invasive cardiac hemodynamic measurements in F(2) crosses between spontaneously hypertensive heart failure (SHHF) rats and ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed3eba14f90743b8c26b6bee6f9bf20
https://doi.org/10.1038/ng.129
https://doi.org/10.1038/ng.129
Autor:
Petra Domaing, Bianca Bertulat, Herbert Schulz, Alessandro Brero, K. Laurence Jost, Norbert Hubner, Alexander Rapp, Tanja Hardt, M. Cristina Cardoso, Claudia Gosele
Publikováno v:
Epigenetics & Chromatin
Background Heterochromatin has been reported to be a major silencing compartment during development and differentiation. Prominent heterochromatin compartments are located at the nuclear periphery and inside the nucleus (e.g., pericentric heterochrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b1ce66681b327b3ff37ff49f0a498f
https://doi.org/10.1186/s13072-015-0025-5
https://doi.org/10.1186/s13072-015-0025-5
Autor:
Erich E. Wanker, Claudia Gosele, T. Kreitler, Heike Zimdahl, Götz Lütjens, Margit Knoblauch, K. Voss, Frank Grützner
Publikováno v:
Cytogenetic and Genome Research. 94:101-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd5c4b0528ea29b632aa677048398128
https://doi.org/10.1159/000048797
https://doi.org/10.1159/000048797
Autor:
Larissa Lebedev, Norbert Hubner, Herbert Schulz, Martin J. Hessner, Yoram Yagil, Claudia Gosele, Ronit Barkalifa, Marina Sapojnikov, Chana Yagil
Publikováno v:
Physiological genomics. (4)
Investigation of proteinuria, whose pathophysiology remains incompletely understood, is confounded by differences in the phenotype between males and females. We initiated a sex-specific geno-transcriptomic dissection of proteinuria in uninephrectomiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2c6d05499b417cd635384fe405549e
https://pubmed.ncbi.nlm.nih.gov/20876844
https://pubmed.ncbi.nlm.nih.gov/20876844
Autor:
Annette Hammes, Pierre Lacombe, Marie Monet-Leprêtre, Anne Joutel, Valérie Domenga, Andreas Schedl, Claudia Gosele, Sabine Schmidt, Barbara Lemaire-Carrette, Norbert Hubner, Céline Baron-Menguy
Cerebral ischemic small vessel disease (SVD) is the leading cause of vascular dementia and a major contributor to stroke in humans. Dominant mutations in NOTCH3 cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencepha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d6408d09653850a6dbad8317672606
https://europepmc.org/articles/PMC2810078/
https://europepmc.org/articles/PMC2810078/
Autor:
Vladimír Křen, Yongming Wang, Drahomíra Křenová, Claudia Gosele, Lucie Šedová, Zsuzsanna Izsvák, František Liška, Norbert Hubner, Zoltán Ivics
Endogenous retroviruses (ERVs) contribute to a range of germline, as well as somatic mutations in mammals. However, autonomous retrotransposition of potentially active elements has not been demonstrated in the rat genome. We cloned an insertion that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa630313fe60e2cef26214b7179f0ee
https://europepmc.org/articles/PMC2798827/
https://europepmc.org/articles/PMC2798827/
Autor:
Petra Domaing, Eliska Krejci, Claudia Gosele, František Liška, Vladimir Kren, M. Cristina Cardoso, Norbert Hubner, Krenová D, Min Ae Lee-Kirsch, Dirk G. de Rooij, Pavel Snajdr, Eugene Rivkin, Abraham L. Kierszenbaum, Laura L. Tres
The hypodactylous (hd) locus impairs limb development and spermatogenesis, leading to male infertility in rats. We show that the hd mutation is caused by an insertion of an endogenous retrovirus into intron 10 of the Cntrob gene. The retroviral inser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02c924b669033f73efc187fa726edc8
https://europepmc.org/articles/PMC2802234/
https://europepmc.org/articles/PMC2802234/
Publikováno v:
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
The goals of physical mapping are to provide (1) an ordered set of all the DNA of the chromosome (or genome), (2) accurate distances between a dense set of DNA markers, and (3) a set of DNA clones from which direct DNA sequencing can be done. High-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9465d5a169d15f85b46faf48bb2d738e
https://doi.org/10.1002/047001153x.g202202
https://doi.org/10.1002/047001153x.g202202