Soluble CD44 in oral rinses for the early detection of cancer: a prospective cohort study in high-risk individuals

Autor: Shahm Raslan, Drew H. Smith, Isildinha M. Reis, Sophia J. Peifer, Garrett Forman, Uche C. Ezeh, Priyashma Joshi, Margaret Koester, Isabella Buitron, Abdurrahman Al-Awady, Jerri Halgowich, Huaping Liu, Claudia Gordon, Monica Webb Hooper, Larissa Sweeny, Elizabeth J. Franzmann

Publikováno v: BMC Oral Health, Vol 24, Iss 1, Pp 1-10 (2024)

Abstract Background There are 54,000 new cases of oral cavity and oropharyngeal cancer in the United States and more than 476,000 worldwide each year. Oral cavity and oropharyngeal squamous cell carcinoma make up most tumors with five-year survival r

Externí odkaz: https://doaj.org/article/2c138b26a096444aa49831be9d28a618

Data from Risk Stratification System for Oral Cancer Screening

Autor: Elizabeth J. Franzmann, Jennifer J. Hu, W. Jarrard Goodwin, Aymee Perez, Penelope Fisher, Stephanie Bayers, Carmen Gomez, Robert Duncan, Sandra Saint-Victor, Claudia Gordon, Erika P. Reategui, Isildinha M. Reis, Lutécia H. Mateus Pereira

Oral cavity and oropharyngeal cancer (oral cancer) is a deadly disease that is increasing in incidence. Worldwide 5-year survival is only 50% due to delayed intervention with more than half of the diagnoses at stage III and IV, whereas earlier detect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7dcb9b2f2919dd50e06cb76acd8bf5
https://doi.org/10.1158/1940-6207.c.6547358

Decreased Levels of Soluble CD44 in a High-Risk Population following a Smoking Cessation Program

Autor: Drew H. Smith, Shahm Raslan, Isildinha M. Reis, Abdurrahman Al-Awady, Isabella Buitron, Melanie Perez, Huaping Liu, Jerri Halgowich, Claudia Gordon, Monica Webb Hooper, Noël C. Barengo, Elizabeth J. Franzmann

Publikováno v: International Journal of Environmental Research and Public Health, Vol 18, Iss 13174, p 13174 (2021)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health; Volume 18; Issue 24; Pages: 13174

Tobacco is a risk factor of head and neck cancer (HNC) and smoking cessation alone may reduce HNC risk by 70%. Soluble CD44 (solCD44), a cell surface receptor linked to cell proliferation and migration, and total protein (TP) levels can detect early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74c50466c04c01d45a8878faa9bd50d
https://doi.org/10.3390/ijerph182413174

Acceptability of a Rinse Screening Test for Diagnosing Head and Neck Squamous Cell Carcinoma Among Black Americans

Autor: Erika P. Reategui, Margaret M. Byrne, Monica Webb Hooper, Claudia Gordon, Suzanne C. Lechner, Marianne Abouyared, David J. Lee, Elizabeth J. Franzmann, Lutecia Pereira

Publikováno v: Journal of racial and ethnic health disparities. 2(1)

Head and neck squamous cell carcinoma (HNSCC) is a debilitating and deadly disease. We evaluated an easy-to-administer and innovative rinse that assays soluble CD44 and total protein as HNSCC early detection markers. We examined whether the rinse was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eef4e8b7c77b4222752736a699148f
https://pubmed.ncbi.nlm.nih.gov/26863243

Abstract B83: Acceptability of a rinse technique for diagnosing head and neck squamous cell carcinoma among African Americans

Autor: Erika P. Reategui, Margaret M. Byrne, Suzanne C. Lechner, Claudia Gordon, Lutecia Pereira, Monica Webb Hooper, Elizabeth J. Franzmann, Jamie L. Studts, David J. Lee

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 21:B83-B83

Background/Objective: Head and neck squamous cell carcinoma (HNSCC) is a debilitating and deadly disease, particularly among African Americans. Cure rates increase from 30% to 80% if the disease is detected early. This study evaluated the acceptabili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03788842f18df48ffc9c1eefda15b34
https://doi.org/10.1158/1055-9965.disp12-b83