Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Claudia Giessler"'
Autor:
Jochen Mattner, Javid P Mohammed, Michael E Fusakio, Claudia Giessler, Carl-Philipp Hackstein, Robert Opoka, Marius Wrage, Regina Schey, Jan Clark, Heather I Fraser, Daniel B Rainbow, Linda S Wicker
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008178 (2019)
Type 1 diabetes (T1D) is a chronic multi-factorial disorder characterized by the immune-mediated destruction of insulin-producing pancreatic beta cells. Variations at a large number of genes influence susceptibility to spontaneous autoimmune T1D in n
Externí odkaz:
https://doaj.org/article/68695eaca1e54bc6800377987faee9a5
Autor:
Stefan Wirtz, Peter J. Oefner, Soeren Lukassen, Raja Atreya, Manfred Rauh, Arndt Hartmann, Mercedes Muske, Claudia Giessler, Harald Arnold, Christoph Daniel, Benjamin Schmid, Ulrike Schleicher, Arif B. Ekici, Jochen Mattner, Christian Bogdan, Philipp Tripal, Maximilian Gänsbauer, Katja Dettmer, Julia L.C. Baier
Publikováno v:
J Clin Invest
Arginase 1 (Arg1), which converts l-arginine into ornithine and urea, exerts pleiotropic immunoregulatory effects. However, the function of Arg1 in inflammatory bowel disease (IBD) remains poorly characterized. Here, we found that Arg1 expression cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090be9d9952b004c55efb162f79c081d
https://pubmed.ncbi.nlm.nih.gov/32721946
https://pubmed.ncbi.nlm.nih.gov/32721946
Autor:
Harald Arnold, Kasper Hoebe, Anna Katharina Koller, Annegret Reinhold, Swen Engelmann, Stephanie Schmidt, Sidonia Mihai, Christian Bogdan, Maike Willers, Christoph Daniel, Hans Parsch, Julia L.C. Baier, Robert Opoka, Stefanie Kliche, Claudia Giessler, Claudia Danzer, Stefan Wirtz, Jochen Mattner
Publikováno v:
European Journal of Immunology. 46:2121-2136
TCR ligation is critical for the selection, activation, and integrin expression of T lymphocytes. Here, we explored the role of the TCR adaptor protein slp-76 on iNKT-cell biology. Compared to B6 controls, slp-76(ace/ace) mice carrying a missense mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8215b585c0a5b15f7eeeb4c765c57780
https://doi.org/10.1002/eji.201646331
https://doi.org/10.1002/eji.201646331