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Autor:
Fred Lisdat, Claudia Gallin, Reinhard Geßner, Jens P. Fürste, Maika Rothkegel, Martin Zydek, Charlotte Förster, Zhiyang Wu
Publikováno v:
Biochemical and Biophysical Research Communications. 419:60-65
‘Locked nucleic acids’ (LNAs) are sugar modified nucleic acids containing the 2′- O -4′ C -methylene- β - d -ribofuranoses. The substitution of RNAs with LNAs leads to an enhanced thermostability. Aptamers are nucleic acids, which are select