Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Claudia G Lopez"'
Autor:
Heekyung Chung, Dennis J Young, Claudia G Lopez, Thuy-Anh T Le, Jeffrey K Lee, Deena Ream-Robinson, Sherry C Huang, John M Carethers
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3463 (2008)
Microsatellite instability promotes colonic tumorigenesis through generating frameshift mutations at coding microsatellites of tumor suppressor genes, such as TGFBR2 and ACVR2. As a consequence, signaling through these TGFbeta family receptors is abr
Externí odkaz:
https://doaj.org/article/27f6e1c85a4d4529b5e913814679c85f
Autor:
Marielle Bassel, Chris Colby, Sumit Saha, Christian Agboton, Brian Bressler, Song Wang, Claudia G. Lopez, Christina Kifnidi, Neil R. Brett, Dirk Demuth, Uri Kopylov, Michelle Luo, Shashi Adsul, Andres Yarur, Gerassimos J. Mantzaris
Publikováno v:
Gastroenterology. 158:S-405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02567274b5e56894e322e6f5b03f04cc
https://doi.org/10.1016/s0016-5085(20)31703-0
https://doi.org/10.1016/s0016-5085(20)31703-0
Autor:
Christian Agboton, Shashi Adsul, Andres Yarur, Hankyul Kim, Sumit Saha, Neil R. Brett, Michelle Luo, Gerassimos J. Mantzaris, Claudia G. Lopez, Song Wang, Christina Kifnidi, Uri Kopylov, Brian Bressler, Marielle Bassel, Dirk Demuth
Publikováno v:
Gastroenterology. 158:S-932
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f9a5bfdef9fc6ebb2635b24466a9188
https://doi.org/10.1016/s0016-5085(20)33011-0
https://doi.org/10.1016/s0016-5085(20)33011-0
Autor:
Chris Colby, Claudia G. Lopez, Christian Agboton, Brian Bressler, Sumit Saha, Uri Kopylov, Dirk Demuth, Marielle Bassel, Song Wang, Andres Yarur, Michelle Luo, Neil R. Brett, Christina Kifnidi, Gerassimos J. Mantzaris, Shashi Adsul
Publikováno v:
Gastroenterology. 158:S-407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dce97965beea3ad7585ce75108d4adcd
https://doi.org/10.1016/s0016-5085(20)31710-8
https://doi.org/10.1016/s0016-5085(20)31710-8
Autor:
Karen Lasch, Claudia G. Lopez, Andres Yarur, Mark T. Osterman, Udayakumar Navaneethan, Alexandra James, Maria Rosario
Publikováno v:
Inflammatory Bowel Diseases. 26:S9-S9
Introduction Vedolizumab (VDZ), a gut-selective antibody that binds specifically to integrin α4β7, is approved for treatment of adults with moderate-to-severe ulcerative colitis (UC). An association between VDZ levels and clinical remission during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad5d2c57b299fcbddfd99fcc2788390
https://doi.org/10.1093/ibd/zaa010.022
https://doi.org/10.1093/ibd/zaa010.022
Autor:
Petros Zezos, Haridarshan Patel, Brian Bressler, Athanasios Natsios, Dirk Demuth, Dara Stein, Andres Yarur, Hankyul Kim, Mark S. Silverberg, Gerassimos J. Mantzaris, Gabriela Radulescu, Trevor Lissoos, Claudia G. Lopez
Publikováno v:
Gastroenterology. 156:S-638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb468bf8cba2d9a7222883923f52a49
https://doi.org/10.1016/s0016-5085(19)38496-3
https://doi.org/10.1016/s0016-5085(19)38496-3
Publikováno v:
Stem Cells. 29:1528-1536
Recent breakthroughs in creating induced pluripotent stem cells (iPSCs) provide alternative means to obtain embryonic stem-like cells without destroying embryos by introducing four reprogramming factors (Oct3/4, Sox2, and Klf4/c-Myc or Nanog/Lin28) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5173725470a90db2f6f9e5d43984cd6
https://doi.org/10.1002/stem.717
https://doi.org/10.1002/stem.717
Publikováno v:
Cancer Biology & Therapy. 10:1147-1156
Several studies indicate that the DNA mismatch repair (MMR) system may trigger cytotoxicity upon 5-fluorouracil (5-FU) recognition, but signaling pathways regulated by MMR in response to 5-FU are unknown. We hypothesize that recognition of 5-FU in DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29653eb8a7f6e32ced9c02715789ffd
https://doi.org/10.4161/cbt.10.11.13447
https://doi.org/10.4161/cbt.10.11.13447
Autor:
Claudia G. Lopez, Deena Ream-Robinson, Joy Holmstrom, Dennis J. Young, Heekyung Chung, John M. Carethers, Betty L. Cabrera, Jenny F. Lai
Publikováno v:
Oncogene
The activin type II receptor (ACVR2) contains two identical microsatellites in exons 3 and 10, but only the exon 10 microsatellite is frameshifted in mismatch repair (MMR)-defective colonic tumors. The reason for this selectivity is not known. We hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fe6f5176d8661c7fe662871927d9f8
https://doi.org/10.1038/onc.2009.508
https://doi.org/10.1038/onc.2009.508
Autor:
Dennis J. Young, Deena Ream-Robinson, Joy Holmstrom, Heekyung Chung, Claudia G. Lopez, John M. Carethers, Jenny F. Lai
It is generally accepted that longer microsatellites mutate more frequently in defective DNA mismatch repair (MMR) than shorter microsatellites. Indeed, we have previously observed that the A 10 microsatellite of transforming growth factor beta type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4893617726d8194bf8a0475d65a76e4c
https://europepmc.org/articles/PMC2912546/
https://europepmc.org/articles/PMC2912546/
