Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claudia Gómez-Liñán"'
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Trypanosomes are single-celled eukaryotes that rely heavily on post-transcriptional mechanisms to regulate gene expression. RNA-binding proteins play essential roles in regulating the fate, abundance and translation of messenger R
Externí odkaz:
https://doaj.org/article/c5c124e01738450b95f6fbd948d60125
Autor:
Lori Ferrins, Melissa J. Buskes, Madison M. Kapteyn, Hannah N. Engels, Suzanne E. Enos, Chenyang Lu, Dana M. Klug, Baljinder Singh, Antonio Quotadamo, Kelly Bachovchin, Westley F. Tear, Andrew E. Spaulding, Katherine C. Forbes, Seema Bag, Mitch Rivers, Catherine LeBlanc, Erin Burchfield, Jeremy R. Armand, Rosario Diaz-Gonzalez, Gloria Ceballos-Perez, Raquel García-Hernández, Guiomar Pérez-Moreno, Cristina Bosch-Navarrete, Claudia Gómez-Liñán, Luis Miguel Ruiz-Pérez, Francisco Gamarro, Dolores González-Pacanowska, Miguel Navarro, Kojo Mensa-Wilmot, Michael P. Pollastri, Dennis E. Kyle, Christopher A. Rice
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0f2b847142f74e518b6ce0db61ac7a90
Autor:
Lori Ferrins, Melissa J. Buskes, Madison M. Kapteyn, Hannah N. Engels, Suzanne E. Enos, Chenyang Lu, Dana M. Klug, Baljinder Singh, Antonio Quotadamo, Kelly Bachovchin, Westley F. Tear, Andrew E. Spaulding, Katherine C. Forbes, Seema Bag, Mitch Rivers, Catherine LeBlanc, Erin Burchfield, Jeremy R. Armand, Rosario Diaz-Gonzalez, Gloria Ceballos-Perez, Raquel García-Hernández, Guiomar Pérez-Moreno, Cristina Bosch-Navarrete, Claudia Gómez-Liñán, Luis Miguel Ruiz-Pérez, Francisco Gamarro, Dolores González-Pacanowska, Miguel Navarro, Kojo Mensa-Wilmot, Michael P. Pollastri, Dennis E. Kyle, Christopher A. Rice
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Acanthamoeba species, Naegleria fowleri, and Balamuthia mandrillaris are opportunistic pathogens that cause a range of brain, skin, eye, and disseminated diseases in humans and animals. These pathogenic free-living amoebae (pFLA) are commonly misdiag
Externí odkaz:
https://doaj.org/article/d32dd50bf4c74ebf995a90e8b2cf426f
Autor:
Claudia Gómez-Liñán, Elena Gómez-Díaz, Gloria Ceballos-Pérez, Sandra M Fernández-Moya, Antonio M Estévez
Publikováno v:
Nucleic Acids Research. 50:12251-12265
In-depth analysis of the transcriptomes of several model organisms has revealed that genomes are pervasively transcribed, giving rise to an abundance of non-canonical and mainly antisense RNA polymerase II-derived transcripts that are produced from a
Autor:
Dana M. Klug, Nelly El-Sakkary, Cristina Bosch-Navarrete, Rosario Diaz-Gonzalez, Gloria Ceballos-Pérez, Guiomar Pérez-Moreno, Jeremiah D. Momper, Carlos Cordon-Obras, Francisco Gamarro, Dolores Gonzalez Pacanowska, Maria Santos Martinez-Martinez, Lori Ferrins, Conor R. Caffrey, Eftychia M. Mavrogiannaki, Katherine C. Forbes, Raquel García-Hernández, Claudia Gómez-Liñán, Miguel Navarro, Andreu Saura, Luis M. Ruiz-Pérez, Pilar Manzano, Ali Syed, Lisseth Silva, Michael P. Pollastri
Publikováno v:
J Med Chem
Neglected tropical diseases such as human African trypanosomiasis (HAT) are prevalent primarily in tropical climates and among populations living in poverty. Historically, the lack of economic incentive to develop new treatments for these diseases ha
Publikováno v:
Nucleic Acids Research
Post-transcriptional regulation of gene expression is particularly important in trypanosomatid protozoa. RNA-binding proteins (RBPs) regulate mRNA stability and translation, yet information about how RBPs are able to link environmental cues to post-t
Autor:
Isabel Vidal-Cobo, Mark Carrington, Miguel Navarro, Alicia Barroso del Jesús, Carlos Cordon-Obras, Diana López-Farfán, Domingo I. Rojas-Barros, Sara Torres-Rusillo, Claudia Gómez-Liñán
Publikováno v:
SSRN Electronic Journal.
Protein-coding genes in the trypanosome genome are organized in polycistronic transcription units (PTUs). How RNA Polymerase II (Pol II) initiates PTU transcription has not been resolved and the current model favors initiation driven by chromatin epi