Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Claudia Friesen"'
Autor:
Claudia Friesen
Publikováno v:
Deutsche Zeitschrift für Onkologie. 49:61-67
ZusammenfassungResistenzen gegenüber konventionellen Behandlungsmethoden limitieren den Erfolg in der Krebstherapie. Dies fordert, neue Therapiestrategien zu entwickeln, um den therapeutischen Erfolg zu verbessern. Krebszellen exprimieren auf ihrer
Publikováno v:
Anticancer Research. 37:1227-1236
Background/Aim: D,L-Methadone increases sensitivity toward chemotherapy of different tumor cell populations. We evaluated the safety and tolerance of additional use of D,L-methadone in patients with glioma in combination with chemotherapy. Patients a
Autor:
Inis Hormann, Mareike Roscher, Claudia Friesen, Josue Moreno, Erich Miltner, Sebastian Marx, Oliver Leib
Publikováno v:
Oncotarget
// Mareike Roscher 1,2 , Inis Hormann 1,2 , Oliver Leib 3 , Sebastian Marx 3 , Josue Moreno 3 , Erich Miltner 1,2 , Claudia Friesen 1,2 1 Centre for Biomedical Research, University of Ulm, Helmholtzstrasse 8/1, Ulm, Germany 2 Institute of Legal Medic
Publikováno v:
Nuklearmedizin. 49:S31-S36
SummaryDespite good achievements in prevention and control, cancer is still a leading cause of death worldwide. The development of resistances against conventional treatment modalities is one of the main causes of failure in the treatment of cancer.
Autor:
Bernd Koop, Klaus-Michael Debatin, Alfred Morgenstern, Gerhard Glatting, Claudia Friesen, Sven N. Reske, Christos Apostolidis, Klaus Schwarz
Publikováno v:
Cancer Research. 67:1950-1958
Chemoresistance and radioresistance are considered one of the primary reasons for therapeutic failure in leukemias and solid tumors. Targeted radiotherapy using monoclonal antibodies radiolabeled with α-particles is a promising treatment approach fo
Autor:
Donald Bunjes, Sven N. Reske, Gerhard Glatting, Anja Dankerl, Peter Liebisch, N. M. Blumstein, Christiane Wendl, Darius Kocot, Claudia Friesen
Publikováno v:
Radiology. 242:498-508
Purpose: To prospectively assess molecular imaging of multiple myeloma (MM) by using the radiolabeled amino acid carbon 11 (11C) methionine and positron emission tomography (PET)/computed tomography (CT). Materials and Methods: The study was approved
Autor:
Sven N. Reske, Andreas K. Buck, Claudia Friesen, Felix M. Mottaghy, Andreas T. J. Vogg, Katrin Wczasek, Bernd Neumaier, Michaela Schmid
Publikováno v:
Nuclear Medicine and Biology. 33:359-366
Several radiolabeled thymidine analogs as metabolic probes of cell proliferation were developed specifically addressing DNA synthesis. Thymidine analogs containing carboranylalkyl groups for neutron capture therapy at the N-3 position were found to b
A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells
Publikováno v:
Cell Death & Differentiation. 11:S73-S85
In chemosensitive leukemias and solid tumors, anticancer drugs have been shown to induce apoptosis. Deficiencies in the apoptotic pathways may lead to chemoresistance. Here we report that glutathione (GSH) plays a critical role in activation of apopt
Autor:
Annelie Lubatschofski, Sven N. Reske, Klaus-Michael Debatin, Claudia Friesen, Inga Buchmann, Joerg Kotzerke
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 30:1251-1261
Beta-irradiation used for systemic radioimmunotherapy (RIT) is a promising treatment approach for high-risk leukaemia and lymphoma. In bone marrow-selective radioimmunotherapy, beta-irradiation is applied using iodine-131, yttrium-90 or rhenium-188 l
Autor:
Andreas Alt, Klaus-Michael Debatin, Inis Hormann, Iduna Fichtner, Claudia Friesen, Erich Miltner, Ralf A. Hilger, Mareike Roscher
Publikováno v:
Cell Cycle
Cell Cycle 13 (10): 1560-1570.
Cell Cycle 13 (10): 1560-1570.
Glioblastoma are the most frequent and malignant human brain tumors, having a very poor prognosis. The enhanced radio- and chemoresistance of glioblastoma and the glioblastoma stem cells might be the main reason why conventional therapies fail. The s