Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Claudia Erpelinck-Verschueren"'
Autor:
Roger Mulet-Lazaro, Stanley van Herk, Margit Nuetzel, Aniko Sijs-Szabo, Noelia Díaz, Katherine Kelly, Claudia Erpelinck-Verschueren, Lucia Schwarzfischer-Pfeilschifter, Hanna Stanewsky, Ute Ackermann, Dagmar Glatz, Johanna Raithel, Alexander Fischer, Sandra Pohl, Anita Rijneveld, Juan M. Vaquerizas, Christian Thiede, Christoph Plass, Bas J. Wouters, Ruud Delwel, Michael Rehli, Claudia Gebhard
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile the epigenome and transcriptome of a subgroup of such leukemias with CpG Island Methylator Phen
Externí odkaz:
https://doaj.org/article/df577d6f414846109f3f3dcf2f2865a4
Autor:
Sophie Ottema, Roger Mulet-Lazaro, Claudia Erpelinck-Verschueren, Stanley van Herk, Marije Havermans, Andrea Arricibita Varea, Michael Vermeulen, H. Berna Beverloo, Stefan Gröschel, Torsten Haferlach, Claudia Haferlach, Bas J. Wouters, Eric Bindels, Leonie Smeenk, Ruud Delwel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Chromosome rearrangements can be a cause of altered oncogene expression in cancer, such as a 3q26 translocation in some acute myeloid leukemias (AML) that leads to overexpression of EVI1. Here the authors engineer this rearrangement in a cell line an
Externí odkaz:
https://doaj.org/article/7df6196de175464e8b50bb614eba9c97
Autor:
Dorien Pastoors, Marije Havermans, Remco Hoogenboezem, Roger Mulet-Lazaro, Duncan Brian, Leonie Smeenk, Claudia Erpelinck-Verschueren, Stanley van Herk, Bas Wouters, Jeroen A.A. Demmers, Johannes Zuber, Tariq Enver, Richard WJ Groen, Eric Bindels, Ruud Delwel
Publikováno v:
Blood. 140:83-84
Autor:
Bronno van der Holt, Jasper Koenders, Remco Hoogenboezem, Berna Beverloo, Pieter Sonneveld, Eric Bindels, Anders Waage, Mathijs A. Sanders, Ivo P. Touw, Paulina M. H. van Strien, Hervé Avet-Loiseau, Kristine Misund, Davine Hofste op Bruinink, Claudia Erpelinck Verschueren
Publikováno v:
Cancer Research. 76:5023-5023
Background Multiple myeloma (MM) is a malignant plasma cell disorder, in which at diagnosis circa 10% of tumors are characterized by a deletion of chromosome 17p (del17p). Previously, others and we reported that this aberration is associated with a s