Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claudia E Weber"'
Autor:
Matthias Wittayer, Claudia E Weber, Maximilian Kittel, Michael Platten, Lucas Schirmer, Hayrettin Tumani, Achim Gass, Philipp Eisele
Publikováno v:
Multiple Sclerosis Journal. 29:549-558
Background: In multiple sclerosis (MS), iron rim lesions (IRLs) are associated with pronounced tissue damage, higher disease severity and have been suggested as an imaging marker of chronic active inflammation behind the blood–brain barrier indicat
Autor:
Matthias Wittayer, Claudia E. Weber, Julia Krämer, Michael Platten, Lucas Schirmer, Achim Gass, Philipp Eisele
Publikováno v:
Magnetic Resonance Imaging. 95:12-18
In multiple sclerosis (MS), iron rim lesions (IRLs) on magnetic resonance imaging (MRI) are associated with pronounced intralesional tissue damage. The aim of this study was to investigate (peri-)lesional and structural connectivity tissue damage in
Autor:
Nicolas Wenzel, Matthias Wittayer, Claudia E. Weber, Michael Platten, Achim Gass, Philipp Eisele
Publikováno v:
Journal of Neuroimaging. 33:240-246
In multiple sclerosis (MS), iron rim lesions (IRLs) are characterized by pronounced tissue matrix damage. The T1/T2-weighted (T1/T2w) ratio represents a postprocessing MRI approach to investigate tissue integrity, but studies investigating spinal cor
Autor:
Philipp Eisele, Matthias Wittayer, Claudia E Weber, Michael Platten, Lucas Schirmer, Achim Gass
Publikováno v:
Multiple Sclerosis Journal. 28:2294-2298
We investigated the impact of disease-modifying therapies (DMTs) on the evolving tissue damage in iron rim multiple sclerosis lesions using a novel post-processing magnetic resonance imaging (MRI) approach, the T1/T2 ratio. In this study, on baseline
Autor:
Johannes Gregori, Florian Weiler, Sigurd Randoll, Stefan Heldmann, Claudia E Weber, Michael Platten, Julia Krämer, Philipp Eisele, Christina Roßmanith, Achim Gass, Matthias Wittayer
Publikováno v:
European Radiology. 32:2012-2022
Objectives In multiple sclerosis (MS), iron rim lesions (IRLs) are indicators of chronic low-grade inflammation and ongoing tissue destruction. The aim of this study was to assess the relationship of IRLs with clinical measures and magnetic resonance
Autor:
Matthias Wittayer, Claudia E Weber, Philipp Eisele, Andreas Dabringhaus, Michael Platten, Achim Gass, Matthias Kraemer
Publikováno v:
Magnetic Resonance Imaging. 79:97-102
Objective Recently, there has been an increasing interest in “chronic enlarging” or “chronic active” multiple sclerosis (MS) lesions that are associated with clinical disability. However, investigation of dynamic lesion volume changes require
Autor:
Alex Förster, Michael Platten, Achim Gass, Philipp Eisele, Claudia E Weber, Christina Roßmanith, Marie T Kleinsorge, Anne Ebert
Publikováno v:
Journal of Neuroimaging. 31:471-474
BACKGROUND AND PURPOSE Internuclear ophthalmoplegia is a dysfunction of conjugate eye movements, caused by lesions affecting the medial longitudinal fasciculus (MLF). Multiple sclerosis (MS) and ischemic stroke represent the most common pathophysiolo
Autor:
Matthias Wittayer, Claudia E. Weber, Michael Platten, Lucas Schirmer, Achim Gass, Philipp Eisele
Publikováno v:
Multiple sclerosis and related disorders. 64
In multiple sclerosis (MS), iron rim lesions (IRLs) on magnetic resonance imaging (MRI) have been suggested as an imaging marker of disease progression. However, the exact mechanisms how they contribute to disability are yet not completely known. Str
Autor:
Nicolas Wenzel, Matthias Wittayer, Claudia E. Weber, Lucas Schirmer, Michael Platten, Achim Gass, Philipp Eisele
Publikováno v:
Journal of neurology. 269(8)
Background In multiple sclerosis (MS), iron rim lesions (IRLs) are characterized by progressive tissue matrix damage. Therefore, early identification could represent an interesting target for therapeutic intervention to minimize evolving tissue damag
Autor:
Philipp, Eisele, Matthias, Kraemer, Andreas, Dabringhaus, Claudia E, Weber, Anne, Ebert, Michael, Platten, Lothar R, Schad, Achim, Gass
Publikováno v:
European journal of neurologyREFERENCES. 28(7)
There has been an increasing interest in chronic active multiple sclerosis (MS) lesions as a new magnetic resonance imaging (MRI) marker of disease progression. Chronic active lesions are characterized by progressive tissue matrix damage, axonal loss