Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Claudia De Sanctis"'
Autor:
Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa, Vishakha Patil, Wan-Ping Lee, Amanda B. Kuzma, Otto Valladares, Laura B. Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, Thomas D. Christie, Robina Afzal, Shrishtee Kandoi, Kristen Whitney, Margaret M. Krassner, Hadley Ressler, SoongHo Kim, Diana Dangoor, Megan A. Iida, Alicia Casella, Ruth H. Walker, Melissa J. Nirenberg, Alan E. Renton, Bergan Babrowicz, Giovanni Coppola, Towfique Raj, Günter U. Höglinger, Ulrich Müller, Lawrence I. Golbe, Huw R. Morris, John Hardy, Tamas Revesz, Tom T. Warner, Zane Jaunmuktane, Kin Y. Mok, Rosa Rademakers, Dennis W. Dickson, Owen A. Ross, Li-San Wang, Alison Goate, Gerard Schellenberg, Daniel H. Geschwind, PSP Genetics Study Group, John F. Crary, Adam Naj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from Alzheimer’s disease (AD) and other diseases, displaying abnormal microtubule-associate
Externí odkaz:
https://doaj.org/article/07eaa87799dd4d0f92bc88b303182da0
Autor:
Seth R Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Jessica X Du, Kathryn R Spencer, Andrea Hartzell, Carol Girgiss, Yusuf T Abaci, Yufeng Shao, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg, Giordano Lippi
Publikováno v:
eLife, Vol 12 (2023)
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of this program. Indeed, deletion of neuron-enriched miRNAs induces strong d
Externí odkaz:
https://doaj.org/article/b595d3de11dc4474b897975c00e26573
Autor:
Salvatore Pulcrano, Roberto De Gregorio, Claudia De Sanctis, Laura Lahti, Carla Perrone-Capano, Donatella Ponti, Umberto di Porzio, Thomas Perlmann, Massimiliano Caiazzo, Floriana Volpicelli, Gian Carlo Bellenchi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6961 (2022)
The development of midbrain dopaminergic (DA) neurons requires a fine temporal and spatial regulation of a very specific gene expression program. Here, we report that during mouse brain development, the microRNA (miR-) 204/211 is present at a high le
Externí odkaz:
https://doaj.org/article/2e6e1d43887349c980e46c0a694c29c2
Autor:
Alessandro Gialluisi, Mafalda Giovanna Reccia, Alfonsina Tirozzi, Teresa Nutile, Alessia Lombardi, Claudia De Sanctis, International Parkinson's Disease Genomic Consortium (IPDGC), Sara Varanese, Sara Pietracupa, Nicola Modugno, Antonio Simeone, Marina Ciullo, Teresa Esposito
Publikováno v:
Frontiers in Neurology, Vol 10 (2020)
Parkinson Disease (PD) is a complex neurodegenerative disorder characterized by large genetic heterogeneity and missing heritability. Since the genetic background of PD can partly vary among ethnicities and neurological scales have been scarcely inve
Externí odkaz:
https://doaj.org/article/2e9da00e809c45858f34fd469f9f4cd4
Autor:
Roberto De Gregorio, Salvatore Pulcrano, Claudia De Sanctis, Floriana Volpicelli, Ezia Guatteo, Lars von Oerthel, Emanuele Claudio Latagliata, Roberta Esposito, Rosa Maria Piscitelli, Carla Perrone-Capano, Valerio Costa, Dario Greco, Stefano Puglisi-Allegra, Marten P. Smidt, Umberto di Porzio, Massimiliano Caiazzo, Nicola Biagio Mercuri, Meng Li, Gian Carlo Bellenchi
Publikováno v:
Stem Cell Reports, Vol 10, Iss 4, Pp 1237-1250 (2018)
Summary: The differentiation of dopaminergic neurons requires concerted action of morphogens and transcription factors acting in a precise and well-defined time window. Very little is known about the potential role of microRNA in these events. By per
Externí odkaz:
https://doaj.org/article/3c07e32b8cbb4c9bbf1ce3db9c93dc16
Autor:
Magdalena Kalinowska, R. Anne McKinney, Yanis Inglebert, Luisa Speranza, Pei You Wu, Anna Francesconi, Claudia De Sanctis
Publikováno v:
J Neurosci
Dendritic spines, actin-rich protrusions forming the postsynaptic sites of excitatory synapses, undergo activity-dependent molecular and structural remodeling. Activation of Group 1 metabotropic glutamate receptors (mGluR1 and mGluR5) by synaptic or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2d9541581e47e9159ec6b1bbb5ef44
https://doi.org/10.1101/2021.09.14.460352
https://doi.org/10.1101/2021.09.14.460352
Autor:
Maribel Donoso, Magdalena Kalinowska, Anna Francesconi, Catherine Castillo, Luisa Speranza, Claudia de Sanctis
Autophagy is an evolutionarily conserved, highly regulated catabolic process critical to neuronal homeostasis, function and survival throughout organismal lifespan. However, the external factors and signals that control autophagy in neurons are still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7de7080610908206397632d8eea470
https://doi.org/10.1101/2020.11.02.365783
https://doi.org/10.1101/2020.11.02.365783
Autor:
Pietro Formisano, Maurizio Forte, Giuseppe Gigliotti, Michelangelo Nigro, Rosita Stanzione, Speranza Rubattu, Davide Viggiano, Giovambattista Capasso, Claudia De Sanctis
Publikováno v:
Journal of molecular histology (Online) 49 (2018): 437–445. doi:10.1007/s10735-018-9782-3
info:cnr-pdr/source/autori:Nigro M.; De Sanctis C.; Formisano P.; Stanzione R.; Forte M.; Capasso G.; Gigliotti G.; Rubattu S.; Viggiano D./titolo:Cellular and subcellular localization of uncoupling protein 2 in the human kidney/doi:10.1007%2Fs10735-018-9782-3/rivista:Journal of molecular histology (Online)/anno:2018/pagina_da:437/pagina_a:445/intervallo_pagine:437–445/volume:49
info:cnr-pdr/source/autori:Nigro M.; De Sanctis C.; Formisano P.; Stanzione R.; Forte M.; Capasso G.; Gigliotti G.; Rubattu S.; Viggiano D./titolo:Cellular and subcellular localization of uncoupling protein 2 in the human kidney/doi:10.1007%2Fs10735-018-9782-3/rivista:Journal of molecular histology (Online)/anno:2018/pagina_da:437/pagina_a:445/intervallo_pagine:437–445/volume:49
The uncoupling protein-2 (UCP2) is an anion transporter that plays a key role in the control of intracellular oxidative stress. In animal models UCP2 downregulation has several pathological sequelae, particularly affecting the vasculature and the kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cddb6d2afd33cbfffa3f7d13ce925d
http://hdl.handle.net/11695/83584
http://hdl.handle.net/11695/83584
Publikováno v:
Psychiatry research
261 (2018): 508–516. doi:10.1016/j.psychres.2018.01.036
info:cnr-pdr/source/autori:De Sanctis C.; Bellenchi G.C.; Viggiano D./titolo:A meta-analytic approach to genes that are associated with impaired and elevated spatial memory performance/doi:10.1016%2Fj.psychres.2018.01.036/rivista:Psychiatry research (Print)/anno:2018/pagina_da:508/pagina_a:516/intervallo_pagine:508–516/volume:261
261 (2018): 508–516. doi:10.1016/j.psychres.2018.01.036
info:cnr-pdr/source/autori:De Sanctis C.; Bellenchi G.C.; Viggiano D./titolo:A meta-analytic approach to genes that are associated with impaired and elevated spatial memory performance/doi:10.1016%2Fj.psychres.2018.01.036/rivista:Psychiatry research (Print)/anno:2018/pagina_da:508/pagina_a:516/intervallo_pagine:508–516/volume:261
Spatial memory deficits are a common hallmark of psychiatric conditions, possibly due to a genetic predisposition. Thus, unravelling the relationship between genes and memory might suggest novel therapeutic targets and pathogenetic pathways. Genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64f1ca355c756a796f87c3437c43c2b
Autor:
Luigi Sironi, Franca Bianchi, Sebastiano Sciarretta, Maurizio Forte, Massimo Volpe, Alice Pignieri, Paolo Gelosa, Maria Cotugno, Claudia De Sanctis, Rosita Stanzione, Simona Marchitti, Michele Madonna, Speranza Rubattu
Publikováno v:
Journal of hypertension. 35(9)
Uncoupling protein-2 (UCP2), a mitochondrial anion transporter involved in mitochondrial uncoupling, limiting reactive oxygen species formation, is significantly downregulated in kidneys of high-salt-fed stroke-prone spontaneously hypertensive rat (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141f4edf2125b35289296b7fdbceda81
https://pubmed.ncbi.nlm.nih.gov/28399045
https://pubmed.ncbi.nlm.nih.gov/28399045