Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claudia Davenport"'
Autor:
Mathias W. Pletz, Andreas Vestergaard Jensen, Christina Bahrs, Claudia Davenport, Jan Rupp, Martin Witzenrath, Grit Barten-Neiner, Martin Kolditz, Sabine Dettmer, James D. Chalmers, Daiana Stolz, Norbert Suttorp, Stefano Aliberti, Wolfgang M. Kuebler, Gernot Rohde
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Introduction Despite improvements in medical science and public health, mortality of community-acquired pneumonia (CAP) has barely changed throughout the last 15 years. The current SARS-CoV-2 pandemic has once again highlighted the central i
Externí odkaz:
https://doaj.org/article/3a8d09ae8671445eab70164e228a35bb
Autor:
Rensheng Wan, Johannes Fänder, Ia Zakaraia, Min Ae Lee-Kirsch, Christine Wolf, Nadja Lucas, Lisa Isabel Olfe, Corinna Hendrich, Danny Jonigk, Dirk Holzinger, Mathis Steindor, Gunnar Schmidt, Claudia Davenport, Christian Klemann, Nicolaus Schwerk, Matthias Griese, Brigitte Schlegelberger, Florian Stehling, Christine Happle, Bernd Auber, Doris Steinemann, Martin Wetzke, Sandra von Hardenberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gain-of-function variants in the stimulator of interferon response cGAMP interactor 1 (STING1) gene cause STING-Associated Vasculopathy with onset in Infancy (SAVI). Previously, only heterozygous and mostly de novo STING1 variants have been reported
Externí odkaz:
https://doaj.org/article/25fe0ff95b034185a86e473bcbc015c8
Autor:
Sarah Sandmann, Yvonne Lisa Behrens, Claudia Davenport, Felicitas Thol, Michael Heuser, Daniela Dörfel, Friederike Löhr, Agnes Castrup, Doris Steinemann, Julian Varghese, Brigitte Schlegelberger, Martin Dugas, Gudrun Göhring
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Patients with myeloid neoplasia are classified by the WHO classification systems. Besides clinical and hematological criteria, cytogenetic and molecular genetic alterations highly impact treatment stratification. In routine diagnostics, a combination
Externí odkaz:
https://doaj.org/article/70d72f9689574fe49058ed0547f90185
Autor:
Martin Schrappe, Beate Kaune, Gudrun Göhring, Claudia Davenport, Maximilian Schieck, Mustafa Salim, Frederik Heldt, Kathrin Thomay, Winfried Hofmann, Yvonne Lisa Behrens, Brigitte Schlegelberger, Jana Lentes, Anja Möricke, Doris Steinemann, Gunnar Cario
Publikováno v:
Genes, Chromosomes and Cancer. 61:22-26
Acute lymphoblastic leukemia (ALL) is the most frequent malignancy in childhood and adolescence. In more than 60% of cases of this heterogeneous disease, a genetic marker is identified via cytogenetic or molecular analyses. TCF3 gene fusions occur in
Autor:
Yvonne Lisa Behrens, Andrea Schienke, Randa Bawadi, Gudrun Göhring, Michael Heuser, Felicitas Thol, Brigitte Schlegelberger, Daria Warnstorf, Thomas Illig, Renate Strasser, Marcel Tauscher, Doris Steinemann, Claudia Davenport, Gunnar Schmidt
Publikováno v:
Genes, chromosomescancerREFERENCES. 60(6)
A complex karyotype, detected in myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), is associated with a reduced median survival. The most frequent chromosomal aberrations in complex karyotypes are deletions of 5q and 17p harboring the
Autor:
Claudia Davenport, Brigitte Schlegelberger, Andrea Schienke, Gudrun Göhring, Yvonne Lisa Behrens, Marcel Tauscher, Stefanie Joachim, Stephanie Knirsch, Mareike Rasche, Jana Lentes, Doris Steinemann, Dirk Reinhardt
Publikováno v:
Cancer genetics.
The co-occurrence of an inversion inv(3)(q21q26)/GATA2-MECOM and a Philadelphia translocation t(9;22)(q34;q11)/BCR-ABL1 in the context of chronic myeloid leukemia (CML) in blast crisis or acute myeloid leukemia (AML) has only rarely been described. T
Autor:
Juliane Ebersold, Azam Salari, Axel Schambach, Brigitte Schlegelberger, Claudia Davenport, Kathrin Thomay, Jana Lentes, Britta Skawran, Gudrun Göhring, Maike Hagedorn
Publikováno v:
Oncotarget
TP53 deficiencies characterize myeloid malignancies with a dismal prognosis. To unravel the pathomechanism of TP53 mutations in the development of myeloid malignancies, we analyzed the functional properties of TP53 conformational and contact mutation
Autor:
Gudrun Göhring, Jana Lentes, Brigitte Schlegelberger, Kathrin Thomay, Maike Hagedorn, Yvonne Lisa Behrens, Gunnar Schmidt, Claudia Davenport, Juliane Ebersold
Publikováno v:
Genes, chromosomescancer. 58(3)
Chromosomal rearrangements involving one donor chromosome and two or more recipient chromosomes are called jumping translocations. To date only few cases of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with jumping translocations h
Publikováno v:
Current Protocols in Stem Cell Biology
Pluripotent stem cells have the capability to differentiate into any somatic cell type of the human body. The generation of surrogate cells for the treatment of liver, lung, and pancreatic diseases is of great medical interest. First, the in vitro fo
Publikováno v:
Journal of Visualized Experiments.
The differentiation capabilities of pluripotent stem cells such as embryonic stem cells (ESCs) allow a potential therapeutic application for cell replacement therapies. Terminally differentiated cell types could be used for the treatment of various d