Meiosis and beyond – understanding the mechanistic and evolutionary processes shaping the germline genome

Autor: Lee Larcombe, Alexander Suh, Yu Sun, Simone Immler, Mette M. Mogensen, Matthew J. Neale, Rebecca E. O’Connor, Ben Skinner, Peter J. I. Ellis, Claudia Cattoni Rathje, Raheleh Rahbari, Alison C Tidy, Ned Peel, D. S. Murray, Iain C. Macaulay, Christian S. Ottolini, Will Nash, Wilfried Haerty, Michael C. Summers, Tarang K. Mehta, Roberta Bergero, Luke Ramsey

Publikováno v: Biological Reviews of the Cambridge Philosophical Society
Bergero, R, Ellis, P, Haerty, W, Larcombe, L, Macaulay, I, Mehta, T, Mogensen, M, Murray, D, Nash, W, Neale, M J, O'Connor, R, Ottolini, C, Peel, N, Ramsey, L, Skinner, B, Suh, A, Summers, M, Sun, Y, Tidy, A, Rahbari, R, Rathje, C & Immler, S 2021, ' Meiosis and beyond – understanding the mechanistic and evolutionary processes shaping the germline genome ', Biological reviews, vol. 96, no. 3, pp. 822-841 . https://doi.org/10.1111/brv.12680

The separation of germ cell populations from the soma is part of the evolutionary transition to multicellularity. Only genetic information present in the germ cells will be inherited by future generations, and any molecular processes affecting the ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5013a65174293a5982c544ce7554251c

Differential Sperm Motility Mediates the Sex Ratio Drive Shaping Mouse Sex Chromosome Evolution

Autor: Côme Ialy-Radio, Julie Cocquet, Giuseppe Silvestri, Deborah Drage, Claudia Cattoni Rathje, Peter J.I. Ellis, Emma Elizabeth Philippa Johnson, Christina Patinioti, Benjamin M. Skinner, Nabeel A. Affara

Publikováno v: Current Biology
Current Biology-CB
Current Biology-CB, 2019, 29 (21), pp.3692-3698.e4. ⟨10.1016/j.cub.2019.09.031⟩

Summary The mouse sex chromosomes exhibit an extraordinary level of copy number amplification of postmeiotically expressed genes [1, 2], driven by an “arms race” (genomic conflict) between the X and Y chromosomes over the control of offspring sex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5f6e917e95462f7bd14084749c6c2d
https://kar.kent.ac.uk/75684/11/PIIS0960982219311935.pdf

A high-throughput method for unbiased quantitation and categorisation of nuclear morphology

Autor: Erica L. Larson, Claudia Cattoni Rathje, Nabeel A. Affara, Peter J.I. Ellis, Gullalaii Yousafzai, Joanne Bacon, Emma Elizabeth Philippa Johnson, Emily Emiko Konishi Kopania, Benjamin M. Skinner, Jeffrey M. Good

Publikováno v: Biology of Reproduction

The physical arrangement of chromatin in the nucleus is cell type and species-specific, a fact particularly evident in sperm, in which most of the cytoplasm has been lost. Analysis of the characteristic falciform (“hook shaped”) sperm in mice is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e1b6d1b547ffe215f976b57e4210e1
https://kar.kent.ac.uk/72160/11/ioz013.pdf

Rapid Multi-Hybridisation FISH Screening for Balanced Porcine Reciprocal Translocations Suggests a Much Higher Abnormality Rate Than Previously Appreciated

Autor: Claudia Cattoni Rathje, Rebecca E. O’Connor, Lucas G. Kiazim, Darren K. Griffin, Rebecca L Jennings

Publikováno v: Cells, Vol 10, Iss 250, p 250 (2021)
Cells
Volume 10
Issue 2

With demand rising, pigs are the world&rsquo
s leading source of meat protein
however significant economic loss and environmental damage can be incurred if boars used for artificial insemination (AI) are hypoprolific (sub-fertile). Growing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d27292a450c15a5ec488d6997e3c566
https://doi.org/10.3390/cells10020250