Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Claudia C, Dos Santos"'
Autor:
Amin M. Ektesabi, Julia Simone, Chirag Vaswani, Greaton W. Tan, Yanbo Wang, Jacqueline L. Pavelick, Xiao Wu, Janice Tai, Sahil Gupta, James N. Tsoporis, Claudia C. dos Santos
Publikováno v:
Oxygen, Vol 4, Iss 1, Pp 20-36 (2024)
Background: Sepsis is a severe and life-threatening condition triggered by a dysregulated response to infection, leading to organ failure and, often, death. The syndrome is expensive to treat, with survivors frequently experiencing reduced quality of
Externí odkaz:
https://doaj.org/article/c9b5a23f869e4a0fbbb4ceeaa075cb55
Autor:
Sandra Palomino-Padilla, Guillermo Caceres-Cardenas, Rodrigo Calderon, Alex C-T. Ko, Lauren Garnett, Kaylie Doan, Patrick Chong, Hammerly Lino, Tatiana Caceres, Teodor Veres, Claudia C. Dos Santos, Birgit Nielsen, Cesar Ugarte-Gil
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
ObjectivesThe COVID-19 pandemic caused a global shortage of nasopharyngeal (NP) swabs, required for RT-PCR testing. Canadian manufacturers were contacted to share NP swab innovations. The primary objective was to determine whether novel NP test swabs
Externí odkaz:
https://doaj.org/article/ec9a3dc73017400d8fc56898488fbf0e
Autor:
Archana Sharma-Oates, PhD, Jack Sullivan, PhD, Daniel Pestana, MSc, Claudia C. dos Santos, MD, Alexandra Binnie, MD, Janet M. Lord, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1044 (2024)
OBJECTIVES:. DNA methylation can be used to determine an individual’s biological age, as opposed to chronological age, an indicator of underlying health status. This study aimed to assess epigenetic age in critically ill patients with and without s
Externí odkaz:
https://doaj.org/article/2f19f1d51ba14835aae3b8c8e75d3143
Autor:
Erblin Cani, Jennifer L. Y. Tsang, Alexandra Binnie, Claudia C. dos Santos, Robert Fowler, Francois Lamontagne, Sangeeta Mehta, Patricia C. Liaw
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/63b77c25ae1d40f8b044ae63cf2ae0ef
Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis
Autor:
Andy Y. An, Arjun Baghela, Peter Zhang, Reza Falsafi, Amy H. Lee, Uriel Trahtemberg, Andrew J. Baker, Claudia C. dos Santos, Robert E. W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSevere COVID-19 and non-COVID-19 pulmonary sepsis share pathophysiological, immunological, and clinical features, suggesting that severe COVID-19 is a form of viral sepsis. Our objective was to identify shared gene expression trajectories
Externí odkaz:
https://doaj.org/article/72fa51db86cf4ba7bc093529d5e48e74
Autor:
Claudia C. dos Santos, Miquéias Lopes-Pacheco, Karen English, Sara Rolandsson Enes, Anna Krasnodembskaya, Patricia R. M. Rocco
Publikováno v:
Cells, Vol 13, Iss 2, p 122 (2024)
Mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) have emerged as innovative therapeutic agents for the treatment of sepsis and acute respiratory distress syndrome (ARDS). Although their potential remains undisputed in pre
Externí odkaz:
https://doaj.org/article/9798bc21629e4bbb9db3e4a4dc4cc632
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-16 (2022)
Abstract Background Sepsis is defined as a state of multisystem organ dysfunction secondary to a dysregulated host response to infection and causes millions of deaths worldwide annually. Novel ways to counteract this disease are needed and such tools
Externí odkaz:
https://doaj.org/article/070fb13ee4484e67ae0e90b51fea712c
Autor:
Mauro Panigada, Elena Spinelli, Stefano De Falco, Dario Consonni, Cristina Novembrino, Massimo Boscolo Anzoletti, Giovanna Panarello, Giovanna Occhipinti, Claudia C. dos Santos, Antonio Pesenti, Antonio Arcadipane, Giacomo Grasselli
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Veno-venous Extracorporeal Membrane Oxygenation (ECMO) is used in the most severe cases of respiratory failure and further exacerbates the patients’ inflammatory status. Antithrombin is supplemented during ECMO for its anticoagulant effect
Externí odkaz:
https://doaj.org/article/5c2d85331fd74b538dc2aa5a6d87c728
Autor:
Andy Y. An, Arjun Baghela, Peter Zhang, Reza Falsafi, Amy H. Lee, Uriel Trahtemberg, Andrew J. Baker, Claudia C. dos Santos, Robert E. W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSevere COVID-19 and non-COVID-19 pulmonary sepsis share pathophysiological, immunological, and clinical features. To what extent they share mechanistically-based gene expression trajectories throughout hospitalization was unknown. Our obj
Externí odkaz:
https://doaj.org/article/7240eb0474994e7cbedec8b7e33d80b4
Autor:
Sabri Soussi, Divya Sharma, Peter Jüni, Gerald Lebovic, Laurent Brochard, John C. Marshall, Patrick R. Lawler, Margaret Herridge, Niall Ferguson, Lorenzo Del Sorbo, Elodie Feliot, Alexandre Mebazaa, Erica Acton, Jason N. Kennedy, Wei Xu, Etienne Gayat, Claudia C. Dos Santos, the FROG-ICU, CCCTBG trans-trial group study for InFACT - the International Forum for Acute Care Trialists
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-12 (2022)
Abstract Background Late mortality risk in sepsis-survivors persists for years with high readmission rates and low quality of life. The present study seeks to link the clinical sepsis-survivors heterogeneity with distinct biological profiles at ICU d
Externí odkaz:
https://doaj.org/article/50e52d67b88a420497ecf9e469cf3324