Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Claudia C, Bauer"'
Autor:
Eulashini Chuntharpursat-Bon, Oleksandr V. Povstyan, Melanie J. Ludlow, David J. Carrier, Marjolaine Debant, Jian Shi, Hannah J. Gaunt, Claudia C. Bauer, Alistair Curd, T. Simon Futers, Paul D. Baxter, Michelle Peckham, Stephen P. Muench, Antony Adamson, Neil Humphreys, Sarka Tumova, Robin S. Bon, Richard Cubbon, Laeticia Lichtenstein, David J. Beech
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
The PIEZO1 channel and the PECAM1 cell adhesion molecule interact and PIEZO1 cooperates with PECAM1 and CDH5 cell junctions during mechanical stress.
Externí odkaz:
https://doaj.org/article/ec77feaa25314fbeac8b7a91697307ac
Autor:
Yin‐Ying Mak, Bi‐Juin Loong, Paul Millns, Claudia C. Bauer, Robin S. Bon, Yvonne Mbaki, Fong‐Kai Lee, Kuan‐Hon Lim, Cin Kong, Sue‐Mian Then, Kang‐Nee Ting
Publikováno v:
Phytotherapy research : PTR. 36(7)
This study investigated the vasorelaxant effects of schwarzinicine A, an alkaloid recently reported from Ficus schwarzii Koord. Regulation of calcium homeostasis in vascular smooth muscle cells (VSMC) is viewed as one of the main mechanisms for contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ed46aab9817f843c304579925473b8
https://pubmed.ncbi.nlm.nih.gov/35537691
https://pubmed.ncbi.nlm.nih.gov/35537691
Autor:
Aisling Minard, Claudia C. Bauer, David J. Wright, Hussein N. Rubaiy, Katsuhiko Muraki, David J. Beech, Robin S. Bon
Publikováno v:
Cells, Vol 7, Iss 6, p 52 (2018)
Proteins of the TRPC family can form many homo- and heterotetrameric cation channels permeable to Na+, K+ and Ca2+. In this review, we focus on channels formed by the isoforms TRPC1, TRPC4 and TRPC5. We review evidence for the formation of different
Externí odkaz:
https://doaj.org/article/ddb1e4adaf8140b6991af15020d491c9
Autor:
Matteo P. Ferla, Anthony H. Keeble, Robin S. Bon, Claudia C. Bauer, Jin Huang, Eulashini Chuntharpursat-Bon, Vikash K. Yadav, Mark Howarth
Summary There are many efficient ways to connect proteins at termini. However, connecting at a loop is difficult because of lower flexibility and variable environment. Here, we have developed DogCatcher, a protein that forms a spontaneous isopeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ac9b6bab21f19f174de28e2499b848
https://ora.ox.ac.uk/objects/uuid:bd3c2dca-5e96-4f79-bc9e-5c05eec20aa4
https://ora.ox.ac.uk/objects/uuid:bd3c2dca-5e96-4f79-bc9e-5c05eec20aa4
Autor:
Katsuhiko Muraki, Aisling Minard, David J. Wright, Isabelle B. Pickles, David J. Beech, Robin S. Bon, Claudia C. Bauer, Melanie J. Ludlow, Stuart L. Warriner, Matthew P. Burnham, Eulashini Chuntharpursat-Bon
Publikováno v:
British Journal of Pharmacology
Background and purpose The TRPC1, TRPC4, and TRPC5 proteins form homotetrameric or heterotetrameric, calcium-permeable cation channels that are involved in various disease states. Recent research has yielded specific and potent xanthine-based TRPC1/4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4e699b9637a2c966805602d09a2869
https://doi.org/10.1111/bph.14791
https://doi.org/10.1111/bph.14791
Autor:
Isabelle B. Pickles, Sara Hosseini-Farahabadi, Claudia C. Bauer, Michel Roberge, Aruna D. Balgi, Robin S. Bon, David J. Beech, Kunho Choi, Alireza Baradaran-Heravi, Linley Dm
Nonsense mutations, which occur in ~11% of patients with genetic disorders, introduce premature termination codons (PTCs) that lead to truncated proteins and promote nonsense-mediated mRNA decay. Aminoglycosides such as gentamicin and G418 permit PTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9eeb5b7b6aba1d3f9c296848304f6e6
https://doi.org/10.1101/2021.04.07.438788
https://doi.org/10.1101/2021.04.07.438788
Autor:
Katie J. Simmons, Robin S. Bon, Claudia C. Bauer, Isabelle B. Pickles, Stuart L. Warriner, David J. Beech, Aisling Minard, Stephen P. Muench, Megan H. Wright, Matthew P. Burnham, Nikil Kapur, Eulashini Chuntharpursat-Bon
TRPC1/4/5 cation channels are emerging drug targets for the treatment of, amongst others, central nervous system (CNS) disorders, kidney disease, and cardiovascular and metabolic disease. Various small-molecule TRPC1/4/5 modulators have been reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163fce96eba849c76ee6326353a6507d
https://eprints.whiterose.ac.uk/165902/1/d0cb00126k.pdf
https://eprints.whiterose.ac.uk/165902/1/d0cb00126k.pdf
Autor:
Matthew P. Burnham, Megan H. Wright, Stephen P. Muench, Isabelle B. Pickles, Aisling Minard, Stuart L. Warriner, Robin S. Bon, Claudia C. Bauer, Nikil Kapur, David J. Beech
TRPC1/4/5 cation channels are emerging drug targets for the treatment of, amongst others, central nervous system (CNS) disorders, kidney disease, and cardiovascular and metabolic disease. Various small-molecule TRPC1/4/5 modulators have been reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb39ed0d9c3afaa6731ca21daf608ae
https://doi.org/10.26434/chemrxiv.11890128.v2
https://doi.org/10.26434/chemrxiv.11890128.v2
Autor:
Camille H. Soubrane, Claudia C. Bauer, Gary J. Stephens, Edward B. Stevens, Peter J. Cox, Venetia Owenson, Manoj K. Patel, Graeme S. Cottrell, Matteo Ottolini, Bryan S. Barker, Michael Rigby, Edward Perez-Reyes, Selvi Ince, James A. Hounshell, Hong Lin
Publikováno v:
The Journal of Neuroscience. 38:9186-9201
The putative cache (Ca2+channel and chemotaxis receptor) domain containing 1 (CACHD1) protein has predicted structural similarities to members of the α2δ voltage-gated Ca2+channel auxiliary subunit family. CACHD1 mRNA and protein were highly expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a0da41285326e674ec480471651597
https://doi.org/10.1523/jneurosci.3572-15.2018
https://doi.org/10.1523/jneurosci.3572-15.2018
Autor:
Claudia C. Bauer, Robin S. Bon, Hussein N. Rubaiy, Katsuhiko Muraki, David J. Beech, Aisling Minard, David J. Wright
Publikováno v:
Cells, Vol 7, Iss 6, p 52 (2018)
Cells
Cells
Proteins of the TRPC family can form many homo- and heterotetrameric cation channels permeable to Na+, K+ and Ca2+. In this review, we focus on channels formed by the isoforms TRPC1, TRPC4 and TRPC5. We review evidence for the formation of different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3ac1253b36c7084bca0bc27bf8fac8
http://www.mdpi.com/2073-4409/7/6/52
http://www.mdpi.com/2073-4409/7/6/52