Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claudia Blattman"'
Autor:
Ewa Koscielniak, Gustaf Ljungman, Bernarda Kazanowska, Felix Niggli, Monika Sparber-Sauer, Rupert Handgretinger, Martin Zimmermann, Joachim Boos, Bernd Blank, Erika Hallmen, Irene Teichert von Lüttichau, Irene Schmid, Birgit Fröhlich, Hermann L. Müller, Wolfgang Behnisch, Ruth Ladenstein, Monika Scheer, Christian Vokuhl, Thekla von Kalle, Claudia Blattmann, Stefan Bielack, Thomas Klingebiel
Publikováno v:
EClinicalMedicine, Vol 78, Iss , Pp 102957- (2024)
Summary: Background: Rhabdomyosarcoma and other soft tissue sarcomas (STS) with high-risk features are still associated with an unsatisfactory outcome. We evaluated the efficacy of oral maintenance therapy added at the end of standard therapy in pati
Externí odkaz:
https://doaj.org/article/f4b2c859be764306b03eebde914a77bd
Autor:
Leo Mascarenhas, Cornelis Martinus van Tilburg, Francois Doz, C. Michel Zwaan, Catherine M. Albert, Claudia Blattman, Birgit Geoerger, Steven G. DuBois, Noah Federman, Ramamoorthy Nagasubramanian, Alberto S. Pappo, Tanya Carens Watt, Ricarda Norenberg, Marc Mardoche Fellous, Esther A. De La Cuesta, Theodore Willis Laetsch, Rui-hua Xu
Publikováno v:
Journal of Clinical Oncology. 40:10030-10030
10030 Background: Neurotrophic tyrosine receptor kinase ( NTRK) gene fusions are oncogenic drivers in various tumor types across all ages. Larotrectinib is a first-in-class, central nervous system (CNS)-active, highly selective tropomyosin receptor k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c72086b52fff2e075f7aaa6f45b7b037
https://doi.org/10.1200/jco.2022.40.16_suppl.10030
https://doi.org/10.1200/jco.2022.40.16_suppl.10030
Autor:
Yang Zhou, Partho Sarothi Ray, Jianguo Zhu, Frank Stein, Mandy Rettel, Thileepan Sekaran, Sudeep Sahadevan, Joel I. Perez-Perri, Eva K. Roth, Ola Myklebost, Leonardo A. Meza-Zepeda, Andreas von Deimling, Chuli Fu, Annika N. Brosig, Kjetil Boye, Michaela Nathrath, Claudia Blattmann, Burkhard Lehner, Matthias W. Hentze, Andreas E. Kulozik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Osteosarcoma is the most common primary malignant bone tumor with a strong tendency to metastasize, limiting the prognosis of affected patients. Genomic, epigenomic and transcriptomic analyses have demonstrated the exquisite molecular comple
Externí odkaz:
https://doaj.org/article/c8a044416b63443ebe99465720d460f3
Autor:
Stefan S. Bielack, Daniel Baumhoer, Stefanie Hecker-Nolting, Simone Hettmer, Leo Kager, Petra Ketteler, Matthias Kevric, Christian P. Kratz, Thomas Kühne, Vanessa Mettmann, Markus Metzler, Dirk Reinhardt, Benjamin Sorg, Claudia Blattmann
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100158- (2024)
Purpose: Many publications address the epidemiology of secondary osteosarcomas following retinoblastoma. Treatment- and outcome-related information is, however, scarce. We used a large cooperative group’s database to study this issue. Patients and
Externí odkaz:
https://doaj.org/article/ebd3c9a7340c4a5fb601494f01178b43
Autor:
Vanessa L. Mettmann, Daniel Baumhoer, Stefan S. Bielack, Claudia Blattmann, Godehard Friedel, Thekla vonKalle, Leo Kager, Matthias Kevric, Michaela Nathrath, Benjamin Sorg, Matthias Dürken, Stefanie Hecker‐Nolting
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 18219-18234 (2023)
Abstract Background To evaluate patient and tumour characteristics, treatment and their impact on survival in patients with a solitary pulmonary metastasis at first relapse of high‐grade osteosarcoma. Procedure Two‐hundred and nineteen consecutiv
Externí odkaz:
https://doaj.org/article/7c87cf91104a4367a88394805f691d43
Autor:
Julia S. Fernandes, Claudia Blattmann, Stefanie Hecker‐Nolting, Leo Kager, Matthias Kevric, Vanessa Mettmann, Benjamin Sorg, Marc Fernandes, Stefan S. Bielack
Publikováno v:
Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Purpose Prognostic factors have been well described for osteosarcoma, but analyses evaluating the further course of long‐term survivors are lacking. We used the large database of the Cooperative Osteosarcoma Study Group (COSS) to perform s
Externí odkaz:
https://doaj.org/article/1462b09b60c446ac950b67b2798bd26d
Autor:
Judith Penkert, Farina J. Strüwe, Christina M. Dutzmann, Beate B. Doergeloh, Emilie Montellier, Claire Freycon, Myriam Keymling, Heinz-Peter Schlemmer, Birte Sänger, Beatrice Hoffmann, Tanja Gerasimov, Claudia Blattmann, Sebastian Fetscher, Michael Frühwald, Simone Hettmer, Uwe Kordes, Vita Ridola, Sabine Kroiss Benninger, Angela Mastronuzzi, Sarah Schott, Juliane Nees, Aram Prokop, Antje Redlich, Markus G. Seidel, Stefanie Zimmermann, Kristian W. Pajtler, Stefan M. Pfister, Pierre Hainaut, Christian P. Kratz
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by pathogenic TP53 variants. The condition represents one of the most relevant genetic causes of cancer in children and adults due to its frequency and high cancer risk. T
Externí odkaz:
https://doaj.org/article/2cb9a5b00a8343d796030d303ca1dcce
Autor:
Hanna IJspeert, Pauline A. van Schouwenburg, Ingrid Pico-Knijnenburg, Jan Loeffen, Laurence Brugieres, Gertjan J. Driessen, Claudia Blattmann, Manon Suerink, Danuta Januszkiewicz-Lewandowska, Amedeo A. Azizi, Marcus G. Seidel, Heinz Jacobs, Mirjam van der Burg
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The generation of high-affinity antibodies depends on somatic hypermutation (SHM). SHM is initiated by the activation-induced cytidine deaminase (AID), which generates uracil (U) lesions in the B-cell receptor (BCR) encoding genes. Error-prone proces
Externí odkaz:
https://doaj.org/article/02fdf5b9344e419387263bfb88fdd747
Autor:
Victoria K. Tesch, Hanna IJspeert, Andrea Raicht, Daniel Rueda, Nerea Dominguez-Pinilla, Luis M. Allende, Chrystelle Colas, Thorsten Rosenbaum, Denisa Ilencikova, Hagit N. Baris, Michaela H. M. Nathrath, Manon Suerink, Danuta Januszkiewicz-Lewandowska, Iman Ragab, Amedeo A. Azizi, Soeren S. Wenzel, Johannes Zschocke, Wolfgang Schwinger, Matthias Kloor, Claudia Blattmann, Laurence Brugieres, Mirjam van der Burg, Katharina Wimmer, Markus G. Seidel
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Immunoglobulin class-switch recombination (CSR) and somatic hypermutations (SHMs) are prerequisites for antibody and immunoglobulin receptor maturation and adaptive immune diversity. The mismatch repair (MMR) machinery, consisting of homologs of MutS
Externí odkaz:
https://doaj.org/article/34b5e5ca683a46b5b6319eb07943d6d2
Publikováno v:
F1000Research, Vol 5 (2016)
Osteosarcoma, a bone cancer most commonly seen in adolescents and young adults, is usually a high-grade malignancy characterized by a very high risk for the development of pulmonary metastases. High-grade osteosarcomas are usually treated by preopera
Externí odkaz:
https://doaj.org/article/3ec6b070271d4aefbc32e2b72deba14f