Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Claudia Binder"'
Autor:
Suganja Chandrabalan, Linh Dang, Uwe Hansen, Melanie Timmen, Corinna Wehmeyer, Richard Stange, Tim Beißbarth, Claudia Binder, Annalen Bleckmann, Kerstin Menck
Publikováno v:
Biological Procedures Online, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract Background Osteoclasts are the tissue-specific macrophage population of the bone and unique in their bone-resorbing activity. Hence, they are fundamental for bone physiology in health and disease. However, efficient protocols for the isolati
Externí odkaz:
https://doaj.org/article/1c6c35f19f30456b964c2af20178a2ad
Autor:
Nadja Schöne, Marcel Kemper, Kerstin Menck, Georg Evers, Carolin Krekeler, Arik Bernard Schulze, Georg Lenz, Eva Wardelmann, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Immunotherapy has revolutionized the treatment of patients with non‐small cell lung cancer (NSCLC). High expression of tissue PD‐L1 (tPD‐L1) is currently the only approved biomarker for predicting treatment response. However, even tPD
Externí odkaz:
https://doaj.org/article/33b401bedfa54e9ba0cbe7aa50c5a449
Autor:
Barnabas Irmer, Janes Efing, Lea Elisabeth Reitnauer, Allegra Angenendt, Saskia Heinrichs, Antonia Schubert, Matthias Schulz, Claudia Binder, Joke Tio, Uwe Hansen, Christiane Geyer, Mirjam Gerwing, Annalen Bleckmann, Kerstin Menck
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Extracellular vesicles (EVs) harbor a plethora of different biomolecules, which they can transport across cells. In cancer, tumor-derived EVs thereby support the creation of a favorable tumor microenvironment. So far, EV uptake an
Externí odkaz:
https://doaj.org/article/2d48326b02b54a75a3384e4a27350f60
Autor:
Kerstin Menck, Saskia Heinrichs, Darius Wlochowitz, Maren Sitte, Helen Noeding, Andreas Janshoff, Hannes Treiber, Torben Ruhwedel, Bawarjan Schatlo, Christian von der Brelie, Stefan Wiemann, Tobias Pukrop, Tim Beißbarth, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Breast cancer has been associated with activation of the WNT signaling pathway, although no driver mutations in WNT genes have been found yet. Instead, a high expression of the alternative WNT receptor ROR2 was observed, in partic
Externí odkaz:
https://doaj.org/article/d0a5a0c967764391a19be071ba9a9dca
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1230-1234 (2020)
Abstract Von Willebrand disease (VWD) is a bleeding disorder caused by qualitative or quantitative defects of von Willebrand factor (VWF). This case report of a patient with systemic sclerosis and gastrointestinal bleeding from angiodysplasias seeks
Externí odkaz:
https://doaj.org/article/f61594d1a5e041ceb0083a2ee1d89c2f
Autor:
Myreisa Morales-Cruz, Nadja E. Solis-Marcano, Claudia Binder, Craig Priest, Carlos R. Cabrera
Publikováno v:
Current Research in Biotechnology, Vol 1, Iss , Pp 22-27 (2019)
An electrochemical whole cell Lab-on-a-Chip sensor for the detection of urea in synthetic urine has been developed. Urea was indirectly monitored by the electrochemical ammonia oxidation liberated by the microbial P. vulgaris microorganism surface me
Externí odkaz:
https://doaj.org/article/c006d7a5913d4fc6a8636a6145a5ac4c
Autor:
Judith Buentzel, Henry Gerd Klemp, Ralph Kraetzner, Matthias Schulz, Gry Helene Dihazi, Frank Streit, Annalen Bleckmann, Kerstin Menck, Darius Wlochowitz, Claudia Binder
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13540 (2021)
Malignant cells differ from benign ones in their metabolome and it is largely unknown whether this difference is reflected in the metabolic profile of their microvesicles (MV), which are secreted into the blood of cancer patients. Here, they are pres
Externí odkaz:
https://doaj.org/article/65e773cb3acc4f6daf595dc149b1f59c
Autor:
Juliane Röthe, Doreen Thor, Jana Winkler, Alexander B. Knierim, Claudia Binder, Sandra Huth, Robert Kraft, Sven Rothemund, Torsten Schöneberg, Simone Prömel
Publikováno v:
Cell Reports, Vol 26, Iss 6, Pp 1573-1584.e5 (2019)
Summary: Insulin secretion from pancreatic β cells is a highly complex and tightly regulated process. Its dysregulation is one characteristic of type 2 diabetes, and thus, an in-depth understanding of the mechanisms controlling insulin secretion is
Externí odkaz:
https://doaj.org/article/817373dca9cf4a059992f6c63eedf44f
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5373 (2020)
Extracellular vesicles (EV) are secreted by all cell types in a tumor and its microenvironment (TME), playing an essential role in intercellular communication and the establishment of a TME favorable for tumor invasion and metastasis. They encompass
Externí odkaz:
https://doaj.org/article/b2bf69b553fe4703a3c80364f8f57e55
Autor:
Kerstin Menck, Can Sönmezer, Thomas Stefan Worst, Matthias Schulz, Gry Helene Dihazi, Frank Streit, Gerrit Erdmann, Simon Kling, Michael Boutros, Claudia Binder, Julia Christina Gross
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
Extracellular vesicles (EVs) are membrane particles secreted from cells into all body fluids. Several EV populations exist differing in size and cellular origin. Using differential centrifugation EVs pelleting at 14,000 g (“microvesicles” (MV)) a
Externí odkaz:
https://doaj.org/article/b3a6837d47e842c9979186d1fe15b4b2