Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Claudia Bilodeau"'
Autor:
Olivia Goltsis, Claudia Bilodeau, Jinxia Wang, Daochun Luo, Meisam Asgari, Laurent Bozec, Ante Pettersson, Sandra L. Leibel, Martin Post
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Chronic lung disease of prematurity, called bronchopulmonary dysplasia (BPD), lacks effective therapies, stressing the need for preclinical testing systems that reflect human pathology for identifying causal pathways and testing n
Externí odkaz:
https://doaj.org/article/45f4836b8b3d47b6a96bf312114b0597
Autor:
Claudia Bilodeau, Sharareh Shojaie, Olivia Goltsis, Jinxia Wang, Daochun Luo, Cameron Ackerley, Ian M Rogers, Brian Cox, Martin Post
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The use of decellularized whole-organ scaffolds for bioengineering of organs is a promising avenue to circumvent the shortage of donor organs for transplantation. However, recellularization of acellular scaffolds from multicellular organs li
Externí odkaz:
https://doaj.org/article/8588797879864052b1564c0cf5b704ba
Autor:
Sandra L. Leibel, Irene Tseu, Anson Zhou, Andrew Hodges, Jun Yin, Claudia Bilodeau, Olivia Goltsis, Martin Post
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103797- (2022)
Summary: Metabolism is vital to cellular function and tissue homeostasis during human lung development. In utero, embryonic pluripotent stem cells undergo endodermal differentiation toward a lung progenitor cell fate that can be mimicked in vitro usi
Externí odkaz:
https://doaj.org/article/e5840d7b4c5240c9ad3d084c50f16741
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 14:521-538
A shortage of donor organs for transplantation and the dependence of the recipients on immunosuppressive therapy have motivated researchers to consider alternative regenerative approaches. The answer may reside in acellular scaffolds generated from c
Autor:
Sandra L. Leibel, Irene Tseu, Anson Zhou, Andrew Hodges, Jun Yin, Claudia Bilodeau, Olivia Goltsis, Martin Post
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103797-(2022)
Summary: Metabolism is vital to cellular function and tissue homeostasis during human lung development. In utero, embryonic pluripotent stem cells undergo endodermal differentiation toward a lung progenitor cell fate that can be mimicked in vitro usi
Autor:
Leonardo Ermini, Behzad Yeganeh, Joyce S. Lee, Cameron Ackerley, Claudia Bilodeau, Jeroen Tibboel, Andre A. Kroon, Isabella Caniggia, Irene Lok, Martin Post
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 199(6), 760-772. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine, 199(6), 760-772. American Thoracic Society
Premature infants subjected to mechanical ventilation (MV) are prone to lung injury that may result in bronchopulmonary dysplasia. MV causes epithelial cell death and halts alveolar development. The exact mechanism of MV-induced epithelial cell death
Autor:
Manon Ruffin, Émilie Maillé, Laura Sognigbé, Claudia Bilodeau, Damien Adam, Emmanuelle Brochiero
Publikováno v:
Journal of Cystic Fibrosis. 17:705-714
Background Progressive airway damage due to bacterial infections, especially with Pseudomonas aeruginosa remains the first cause of morbidity and mortality in CF patients. Our previous work revealed a repair delay in CF airway epithelia compared to n
Autor:
Brian J. Cox, Sharareh Shojaie, Claudia Bilodeau, Daochun Luo, Martin Post, Ian M. Rogers, Cameron Ackerley, Jinxia Wang, Olivia Goltsis
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
The use of decellularized whole-organ scaffolds for bioengineering of organs is a promising avenue to circumvent the shortage of donor organs for transplantation. However, recellularization of acellular scaffolds from multicellular organs like the lu
Autor:
Janet Rossant, Jodi Garner, Amy P. Wong, Saumel Ahmadi, Claudia Bilodeau, Thomas K. Waddell, Qin Liang, Andras Nagy, Michelle Di Paola, Sunny Xia, Martin Post, Pascal Duchesneau, Sharareh Shojaie, Christine E. Bear
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Cell lineage conversion of fibroblasts to specialized cell types through transdifferentiation may provide a fast and alternative cell source for regenerative medicine. Here we show that transient transduction of fibroblasts with the four reprogrammin
Autor:
Dao Nguyen, Claudia Bilodeau, Émilie Maillé, Nguyen Thu Ngan Trinh, Martin-Yvon Desrosiers, Geoffrey McKay, Shantelle L. LaFayette, Emmanuelle Brochiero, Simon Rousseau, Manon Ruffin, Trevor Beaudoin
Publikováno v:
The FASEB Journal. 30:3011-3025
Chronic Pseudomonas aeruginosa lung infections are associated with progressive epithelial damage and lung function decline. In addition to its role in tissue injury, the persistent presence of P. aeruginosa–secreted products may also affect epithel