Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Claudia Benkwitz"'
Autor:
Claudia Benkwitz, Robert A. Pearce, Alexander G Figueroa, Nicholas A. Kunz, Gregg E. Homanics, Gabe Surges
Publikováno v:
Journal of Neurophysiology. 126:1090-1100
Etomidate exerts its anesthetic actions through GABAA receptors. However, the mechanism remains unknown. Here, using a hippocampal brain slice model, we show that β2-GABAARs are essential to this effect. We also show that these receptors contribute
Autor:
Alexander G, Figueroa, Claudia, Benkwitz, Gabe, Surges, Nicholas, Kunz, Gregg E, Homanics, Robert A, Pearce
Publikováno v:
J Neurophysiol
The general anesthetic etomidate, which acts through γ-aminobutyric acid type A (GABA(A)) receptors, impairs the formation of new memories under anesthesia. This study addresses the molecular and cellular mechanisms by which this occurs. Here, using
Publikováno v:
Seminars in cardiothoracic and vascular anesthesia. 24(4)
Literature on posterior mediastinal masses is limited. Furthermore, they have traditionally been described to pose lower cardiopulmonary risks compared with anterior mediastinal masses. Studies on posterior mediastinal masses are even more limited in
Autor:
Ellen Spurrier, Edmund H. Jooste, Dheeraj Goswami, Claudia Benkwitz, Gregory J. Latham, Jamie M. Schwartz, Kelly A. Machovec, Manchula Navaratnam, Matthew R. McDaniel, Luis M. Zabala, Lisa Wise-Faberowski, David Faraoni, Nina A. Guzzetta, Nischal K. Gautam, Laura A. Downey, Stephanie E. Jones, Erin A. Gottlieb
Publikováno v:
Anesthesia and analgesia. 128(5)
Autor:
H. Mayumi Homi, Yi Hung Wu, Rebecca Scholl, Edmund H. Jooste, Brian S. Donahue, Kelly A. Machovec, Robert Douglas Benjamin Jaquiss, Nathaniel H. Greene, Nirmish Shah, Warwick A. Ames, Andrew J. Lodge, Claudia Benkwitz
Publikováno v:
Journal of cardiothoracic and vascular anesthesia, vol 33, iss 2
Jooste, EH; Scholl, R; Wu, Y-H; Jaquiss, RDB; Lodge, AJ; Ames, WA; et al.(2018). Double-Blind, Randomized, Placebo-Controlled Trial Comparing the Effects of Antithrombin Versus Placebo on the Coagulation System in Infants with Low Antithrombin Undergoing Congenital Cardiac Surgery.. Journal of cardiothoracic and vascular anesthesia. doi: 10.1053/j.jvca.2018.05.052. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8rh2k10f
Jooste, EH; Scholl, R; Wu, Y-H; Jaquiss, RDB; Lodge, AJ; Ames, WA; et al.(2018). Double-Blind, Randomized, Placebo-Controlled Trial Comparing the Effects of Antithrombin Versus Placebo on the Coagulation System in Infants with Low Antithrombin Undergoing Congenital Cardiac Surgery.. Journal of cardiothoracic and vascular anesthesia. doi: 10.1053/j.jvca.2018.05.052. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8rh2k10f
Objectives To determine whether precardiopulmonary bypass (CPB) normalization of antithrombin levels in infants to 100% improves heparin sensitivity and anticoagulation during CPB and has beneficial effects into the postoperative period. Design Rando
Publikováno v:
Anesthesiology. 101:924-936
Background Gamma-aminobutyric acid type A (GABAA) receptors, the major inhibitory receptors in the brain, are important targets of many drugs, including general anesthetics. These compounds exert multiple effects on GABAA receptors, including direct
Publikováno v:
Journal of the American College of Cardiology. 67(7):802-803
Children with congenital heart disease (CHD) who were once considered “inoperable” are increasingly living into adulthood with improved quality of life. By some accounts, there are now more adults than children living with CHD [(1)][1]. This turn
Publikováno v:
Anesthesiology. 99:1093-1101
Background Local anesthetics inhibit several G protein-coupled receptors by interaction with the Galphaq protein subunit. It is not known whether this effect on G protein function can be extrapolated to other classes of G proteins. The authors invest
Publikováno v:
Biochemical and Biophysical Research Communications. 261:515-520
In recent theories concerning the pathogenesis of essential hypertension, altered calcium homeostasis plays an important role. Increased intracellular Ca 2+ levels have repeatedly been reported in different cell types of hypertensive subjects. In vas
Autor:
Frank Gollnick, Kai Schuh, Hong Han, Ursula Ganten, Peter Gaudron, Kai Hu, Claudia Benkwitz, Katja Nething, Roland Vetter, Annette Hammes, Rainer Meyer, Ludwig Neyses, Tobias Rother, Klaus W. Linz, Silke Oberdorf-Maass, Hans G. Zimmer, Sigrid Hoffmann, Georg Ertl
Publikováno v:
Circulation Research. 83:877-888
Abstract —The plasma membrane calmodulin–dependent calcium ATPase (PMCA) is a calcium-extruding enzyme controlling Ca 2+ homeostasis in nonexcitable cells. However, its function in the myocardium is unclear because of the presence of the Na + /Ca