Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claudia Ben Dov"'
Autor:
Felice-Alessio Bava, Juan Valcárcel, Carolina Eliscovich, Roderic Guigó, Raúl Méndez, Belén Miñana, Pedro G. Ferreira, Claudia Ben-Dov
Publikováno v:
Nature. 495:121-125
More than half of mammalian genes generate multiple messenger RNA isoforms that differ in their 3' untranslated regions (3' UTRs) and therefore in regulatory sequences, often associated with cell proliferation and cancer; however, the mechanisms coor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5345e087d3b0cbf42c6e0f743547580
https://doi.org/10.1038/nature11901
https://doi.org/10.1038/nature11901
Publikováno v:
Journal of Biological Chemistry. 283:1229-1233
Alternative splicing of mRNA precursors allows the synthesis of multiple mRNAs from a single primary transcript, significantly expanding the information content and regulatory possibilities of higher eukaryotic genomes. High-throughput enabling techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca8bf01b93f0d962a3be059de84b181
https://doi.org/10.1074/jbc.r700033200
https://doi.org/10.1074/jbc.r700033200
Autor:
Arthur H.M. Burghes, Bettina Heinrich, Laurent Bracco, Tatyana Novoyatleva, Claudia Ben-Dov, Yesheng Tang, Monique A. Lorson, Pascale Fehlbaum, Natalya Benderska, Christian L. Lorson, Mathieu Bollen, Stefan Stamm, Matthew E.R. Butchbach
Publikováno v:
Human Molecular Genetics. 17:52-70
Alternative splicing emerges as one of the most important mechanisms to generate transcript diversity. It is regulated by the formation of protein complexes on pre-mRNA. We demonstrate that protein phosphatase 1 (PP1) binds to the splicing factor tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2774973efe7cab5e52246148f2facb86
https://doi.org/10.1093/hmg/ddm284
https://doi.org/10.1093/hmg/ddm284
Autor:
Ruben Alves, Maria Carmo-Fonseca, Claudia Ben-Dov, Ray Staller, Pedro Eleutério, Tito Santos Silva, Ana Rita Grosso, Inês Mollet, Daniel Felício-Silva
Publikováno v:
Nucleic Acids Research
Mining massive amounts of transcript data for alternative splicing information is paramount to help understand how the maturation of RNA regulates gene expression. We developed an algorithm to cluster transcript data to annotated genes to detect unan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b7061fbaed740e0b91851d973bc6cb
https://hdl.handle.net/10400.14/38681
https://hdl.handle.net/10400.14/38681
Autor:
Claudia Ben-Dov, Troy Moore, Martin P. Vazquez, Hernan Lorenzi, Mariano J. Levin, Alejandro G. Schijman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(5)
The short interspersed repetitive element (SIRE) of Trypanosoma cruzi was first detected when comparing the sequences of loci that encode the TcP2β genes. It is present in about 1,500-3,000 copies per genome, depending on the strain, and it is distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2a7c0cf1480e48f4fc907c7fc9c150
https://pubmed.ncbi.nlm.nih.gov/10688909
https://pubmed.ncbi.nlm.nih.gov/10688909
Publikováno v:
Gene. 239(2)
The short interspersed repetitive element (SIRE) of the nuclear genome of Trypanosoma cruzi was first detected when comparing the sequences of loci that encode the TcP2beta genes. The present study was designed to assess its distribution and organiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ade802c0f1b0d068521a2b7f766a71a
https://pubmed.ncbi.nlm.nih.gov/10548721
https://pubmed.ncbi.nlm.nih.gov/10548721
Autor:
Herzel Ben-Shlomo, Yu-Xin Xu, Yafei Zhang, Shulamit Michaeli, Claudia Ben-Dov, Alexander Levitan
Trypanosomes possess unique RNA processing mechanisms including trans- splicing of pre-mRNA and RNA editing of mitochondrial transcripts. The previous finding of a trimethylguanosine (TMG) capped U3 homologue in trypanosomes suggests that rRNA proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0761f9b3dce2e008531e3dba4a62942
https://europepmc.org/articles/PMC147474/
https://europepmc.org/articles/PMC147474/
Autor:
Hernan Lorenzi, Sergio Ghio, Claudia Ben Dov, Mariano J. Levin, Martin P. Vazquez, Alejandro G. Schijman
Publikováno v:
Biochimica et biophysica acta. 1264(1)
P2β acidic ribosomal protein is a relevant antigen in Chagas' disease. cDNA cloning demonstrated that Trypanosoma cruzi expresses at least six types of TcP2β transcripts that differed by point nucleotides substitutions. The distribution and type of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e661878322b86adf6209b2c164f349
https://pubmed.ncbi.nlm.nih.gov/7578249
https://pubmed.ncbi.nlm.nih.gov/7578249
Autor:
Manuel J. Muñoz, Juan José Lozano, Edouard Bertrand, Claudia Ben-Dov, Manuel de la Mata, Alberto R. Kornblihtt, Federico Pelisch, Maria Paola Paronetto, David Bentley, M. Soledad Pérez Santangelo, Stéphanie Boireau, Matías Blaustein, Kira Glover-Cutter, Gregory H. Bird
Publikováno v:
Cell. 139:211
SummaryDNA damage induces apoptosis and many apoptotic genes are regulated via alternative splicing (AS), but little is known about the control mechanisms. Here we show that ultraviolet irradiation (UV) affects cotranscriptional AS in a p53-independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b4eae3716f2c715955b50ebc033769
https://doi.org/10.1016/j.cell.2009.09.022
https://doi.org/10.1016/j.cell.2009.09.022
Autor:
Claudia Hartmann, Maciej Drozdz, Martina Ding, Marina Cristodero, Cristina Guerra-Giraldez, Luis Quijada, Christine Clayton, Claudia Ben-Dov, Henriette Irmer
Publikováno v:
Scopus-Elsevier
The salivarian trypanosome Trypanosoma brucei infects mammals and is transmitted by tsetse flies. The mammalian ‘bloodstream form’ trypanosome has a variant surface glycoprotein coat and relies on glycolysis while the procyclic form from tsetse f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b18a9f84b88f3e2735f87694c3ec03e
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037109118&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037109118&partnerID=MN8TOARS