Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Claudia Behm"'
Publikováno v:
Archives of Toxicology. 88:1097-1107
Citrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by several species of the genera Aspergillus, Penicillium and Monascus. Both can be present as contaminants in various food commodities and in animal feed. The occurrence and toxicity of O
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 75:1206-1215
N-Acetyltransferases (NAT) are important enzymes in the metabolism of certain carcinogenic arylamines, as N-acetylation decreases or prevents their bioactivation via N-hydroxylation. To study such processes in the bladder, cell culture models may be
Publikováno v:
Archives of toxicology. 88(6)
The toxic heavy metals cadmium (Cd) and lead (Pb) are important environmental pollutants which can cause serious damage to human health. As the metal ions (Cd2+ and Pb2+) accumulate in the organism, there is special concern regarding chronic toxicity
Publikováno v:
Journal of toxicology and environmental health. Part A. 75(19-20)
Cigarette smoking is a risk factor for bladder cancer. Since urothelial cells express phase I and II enzymes these cells are able to metabolize precarcinogens into DNA reactive intermediates. Cigarette smoke is a complex mixture containing at least 8
Publikováno v:
Journal of toxicology and environmental health. Part A. 75(19-20)
In addition to dietary mycotoxin intake, exposure by inhalation is possible and may result in local effects in the lung. As a first approach to assess the potential local impact of inhaled mycotoxins, the cytotoxicity of 14 different mycotoxins was d
Publikováno v:
Molecular nutritionfood research. 53(4)
Enniatin B, a fungal metabolite produced by various Fusarium strains, is a frequent contaminant in cereals used for human foods and animal feeds, but, so far very limited data are available on its toxicity. The aim of this study was to investigate th
Autor:
Jürgen Kuhlmann, Claudia Behm, Peter H. Roos, Jan G. Hengstler, Alexandra Borza, Silvia Selinski, Alexander Wolf, Wolfram Föllmann, Hermann M. Bolt, Sabine Plöttner
Publikováno v:
Archives of toxicology. 82(12)
Aromatic amines have been shown to cause bladder cancer. However, epithelial cells of the urinary bladder, cells of origin of bladder cancer, may be exposed to numerous substances besides aromatic amines. In the present study, we analysed possible in
Publikováno v:
Mycotoxin research. 25(1)
The Fusarium metabolite enniatin B is now recognized as a frequent contaminant of grains used for human foods and animal feeds. Yet, so far very limited data are available on its toxicity and that of other emerging Fusarium mycotoxins (Jestoi M, 2008
Publikováno v:
Journal of toxicology and environmental health. Part A. 71(13-14)
Benzo[a]pyrene (BaP) is an environmental pollutant used as a key marker substance for polycyclic aromatic hydrocarbons (PAHs). PAHs are believed to play a prominent role in the development of bladder cancer. A test system based on primary porcine uri
Publikováno v:
Mycotoxin research. 23(2)
In order to better characterize the ochratoxin A (OTA)-induced DNA damage and to further investigate factors which may modulate dose-effect relationships in cells, the induction of micronuclei was studied in V79 Chinese hamster fibroblast cells and i