Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claudia Beaurivage"'
Autor:
Claudia Beaurivage, Auste Kanapeckaite, Cindy Loomans, Kai S. Erdmann, Jan Stallen, Richard A. J. Janssen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Inflammatory bowel disease (IBD) is a complex multi-factorial disease for which physiologically relevant in vitro models are lacking. Existing models are often a compromise between biological relevance and scalability. Here, we integrated in
Externí odkaz:
https://doaj.org/article/5ee09f4d5dd6420bbe0cfc533c9d9934
Autor:
Soura Mardpour, Claudia Beaurivage, Jane Sun, Lorenz Jahn, Rene Overmeer, Lars-Eric Fielmich, Pleun Hombrink, Farzin Pourfarzad, Sylvia F. Boj
Publikováno v:
Cancer Research. 83:188-188
Recent advances in cancer immunotherapy had a positive impact on the life expectancy of patients for a large range of clinical indications. With new treatment strategies and druggable targets being identified at an increasing pace, the number of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88b8aa354534ef9d9d75643cdd4eca2
https://doi.org/10.1158/1538-7445.am2023-188
https://doi.org/10.1158/1538-7445.am2023-188
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:4197-4207
Target evaluation is at the centre of rational drug design and biologics development. In order to successfully engineer antibodies, T-cell receptors or small molecules it is necessary to identify and characterise potential binding or contact sites on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95deba2088bbb0f5fb3bf7db896901d1
https://doi.org/10.1080/07391102.2020.1854859
https://doi.org/10.1080/07391102.2020.1854859
Autor:
Auste Kanapeckaite, Claudia Beaurivage, Kai S. Erdmann, Cindy Loomans, Richard Antonius Jozef Janssen, Jan Stallen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Inflammatory bowel disease (IBD) is a complex multi-factorial disease for which physiologically relevant in vitro models are lacking. Existing models are often a compromise between biological relevance and scalability. Here, we integrated intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e06b96b02f87796f67b210625a1d262
https://doaj.org/article/5ee09f4d5dd6420bbe0cfc533c9d9934
https://doaj.org/article/5ee09f4d5dd6420bbe0cfc533c9d9934
Publikováno v:
Biophysical chemistry. 276
Target evaluation and rational drug design rely on identifying and characterising small-molecule binding sites on therapeutically relevant target proteins. Immunotherapeutics development is especially challenging because of complex disease etiology a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004084f54cef7dd1dfb97b85ddbdd891
https://pubmed.ncbi.nlm.nih.gov/34087524
https://pubmed.ncbi.nlm.nih.gov/34087524
Autor:
Gerardo Ferbeyre, Caroline Saucier, Véronique Pomerleau, Mehdi Yeganeh, Audrey Champagne, W. S. Tobelaim, Julie Carrier, Subburaj Ilangumaran, Roscoe Klinck, Philippe Thibault, Claudia Beaurivage, Aline Simoneau, Walid Chababi
Publikováno v:
Scientific Reports
The SOCS1 (Suppressor Of Cytokine Signalling 1) protein is considered a tumour suppressor. Notably, the SOCS1 gene is frequently silenced in cancer by hypermethylation of its promoter. Besides blocking inflammation, SOCS1 tumour suppressor activity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9beb3140cf90cad85e2a6eace73f775d
http://europepmc.org/articles/PMC4585755
http://europepmc.org/articles/PMC4585755
Autor:
Jan Stallen, Dorota Kurek, Richard A.J. Janssen, Kai S. Erdmann, Henriëtte L. Lanz, Arnaud Nicolas, Jos Joore, Yee Xiang Chang, Claudia Beaurivage, Edo D. Elstak, Sebastiaan Johannes Trietsch, Paul Vulto, Elena Naumovska, Guido van Moolenbroek, Heidi Wouters
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 22
Volume 20
Issue 22
A common bottleneck in any drug development process is finding sufficiently accurate models that capture key aspects of disease development and progression. Conventional drug screening models often rely on simple 2D culture systems that fail to recap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa65558b0a3505cf5b7058ca67af61d