Výsledky vyhledávání - "Claudia Antonissen"

Expression of Endothelial Nitric Oxide Synthase and Endothelin-1 in Skin Tissue from Amputated Limbs of Patients with Complex Regional Pain Syndrome

Autor: Claudia Antonissen, Freek J. Zijlstra, J. George Groeneweg, Frank J P M Huygen

Publikováno v: Mediators of Inflammation, Vol 2008 (2008)
Mediators of Inflammation
Mediators of Inflammation, 2008:680981. Hindawi Publishing Corporation

Background and Objectives. Impaired microcirculation during the chronic stage of complex regional pain syndrome (CRPS) is related to increased vasoconstriction, tissue hypoxia, and metabolic tissue acidosis in the affected limb. Endothelial dysfuncti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec0cc6f8055b6948e20aa3c71ed19ab
https://doi.org/10.1155/2008/680981

Zobrazit plný text záznamu

Somatostatin is a selective chemoattractant for primitive (CD34+) hematopoietic progenitor cells

Autor: Sigrid P M A Oomen, Paula B. van Hennik, Leo J. Hofland, Ivo P. Touw, Steven W. J. Lamberts, Claudia Antonissen, Bob Löwenberg, Elgin G. R. Lichtenauer-Kaligis

Publikováno v: Experimental Hematology, 30(2), 116-125. Elsevier Inc.

Objective Somatostatin (SST) is a regulatory peptide with a wide variety of activities in different tissues. SST activates G αi -protein-coupled receptors of a family comprising five members (SSTR1–5). Despite the broad use of SST and its analogs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16db220f94edd8b09ff41039a8bd71b
https://doi.org/10.1016/s0301-472x(01)00772-x

Zobrazit plný text záznamu

Sustained Receptor Activation and Hyperproliferation in Response to Granulocyte Colony-stimulating Factor (G-CSF) in Mice with a Severe Congenital Neutropenia/Acute Myeloid Leukemia–derived Mutation in the G-CSF Receptor Gene

Autor: Angelique E. M. Mayen, Alister C. Ward, Ivo P. Touw, Rob E. Ploemacher, Claudia Antonissen, Mirjam H. A. Hermans

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, 189(4), 683-691. Rockefeller University Press

In approximately 20% of cases of severe congenital neutropenia (SCN), mutations are found in the gene encoding the granulocyte colony-stimulating factor receptor (G-CSF–R). These mutations introduce premature stop codons, which result in truncation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8636b17b10e871386d2f3f8d4e8685b2
https://doi.org/10.1084/jem.189.4.683

Zobrazit plný text záznamu

Tyrosine-Dependent and -Independent Mechanisms of STAT3 Activation by the Human Granulocyte Colony-Stimulating Factor (G-CSF) Receptor Are Differentially Utilized Depending on G-CSF Concentration

Autor: Yvette M. van Aesch, Anita M. Schelen, Ivo P. Touw, Alister C. Ward, Mirjam H. A. Hermans, Louise Smith, Claudia Antonissen

Publikováno v: Blood, 93(1), 113-124. American Society of Hematology

The granulocyte colony-stimulating factor receptor (G-CSF-R) activates multiple STAT proteins. Although the membrane-proximal cytoplasmic region of the G-CSF-R is necessary and sufficient for activation of STAT1 and STAT5, activation of STAT3 require

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dedb2806bc14ef820320c617c0588d
https://doi.org/10.1182/blood.v93.1.113.401k33_113_124

Zobrazit plný text záznamu

Perturbed Granulopoiesis in Mice With a Targeted Mutation in the Granulocyte Colony-Stimulating Factor Receptor Gene Associated With Severe Chronic Neutropenia

Autor: Alar Karis, Claudia Antonissen, Alister C. Ward, Ivo P. Touw, Mirjam H. A. Hermans, Bob Löwenberg

Publikováno v: Blood, 92(1), 32-39. American Society of Hematology

Mutations in the granulocyte colony-stimulating factor (G-CSF) receptor gene are found in a number of patients with severe chronic neutropenia predisposed to acute myeloid leukemia. These mutations result in the absence of the C-terminal domain of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0117abce9ef269e39c0afa5066199005
https://doi.org/10.1182/blood.v92.1.32.413k42_32_39

Zobrazit plný text záznamu

Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

Autor: Mirjam H. A. Hermans, Gert-Jan M van de Geijn, Daphne van Leeuwen, Alister C. Ward, Touw I, Judith Gits, Claudia Antonissen

Publikováno v: Blood, 101, 2584-2590. American Society of Hematology

Granulocyte colony-stimulating factor (G-CSF) is the major regulator of neutrophil production. Studies in cell lines have established that conserved tyrosines Tyr704, Tyr729, Tyr744, Tyr764 within the cytoplasmic domain of G-CSF receptor (G-CSF-R) co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b393179d8fc2c9b5d0c54fb2d15e369
https://pure.eur.nl/en/publications/14a5c837-5367-4db5-9323-54b67bf19787

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání