Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Claudia Agarinis"'
Autor:
Fanning Zeng, Valerie Beck, Sven Schuierer, Isabelle Garnier, Carole Manneville, Claudia Agarinis, Lapo Morelli, Lisa Quinn, Judith Knehr, Guglielmo Roma, Frederic Bassilana, Mark Nash
Publikováno v:
Cells, Vol 9, Iss 12, p 2618 (2020)
Genetic knock-in using homology-directed repair is an inefficient process, requiring the selection of few modified cells and hindering its application to primary cells. Here, we describe Homology independent gene Tagging (HiTag), a method to tag a pr
Externí odkaz:
https://doaj.org/article/207e3525506d4404aad26823f2702e3d
Autor:
Matthias D. Sury, Lorianne Vorlet-Fawer, Claudia Agarinis, Shida Yousefi, Denis Grandgirard, Stephen L. Leib, Stephan Christen
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 1, Pp 201-208 (2011)
Pneumococcal meningitis causes apoptosis of developing neurons in the dentate gyrus of the hippocampus. The death of these cells is accompanied with long-term learning and memory deficits in meningitis survivors. Here, we studied the role of the PI3K
Externí odkaz:
https://doaj.org/article/6eaca995054e41368bdcf1b79a82551f
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 1, Pp 142-150 (2008)
Pneumococcal meningitis is associated with caspase 3-dependent apoptosis of recently post-mitotic immature neurons in the dentate gyrus of the hippocampus. The death of these cells is implicated in the learning and memory deficits in patients survivi
Externí odkaz:
https://doaj.org/article/acd9d6c8ebe443348b01e6d43a5f8a48
Autor:
Claudia Stein, Anaïs Flore Bardet, Guglielmo Roma, Sebastian Bergling, Ieuan Clay, Alexandra Ruchti, Claudia Agarinis, Tobias Schmelzle, Tewis Bouwmeester, Dirk Schübeler, Andreas Bauer
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005465 (2015)
YAP1 is a major effector of the Hippo pathway and a well-established oncogene. Elevated YAP1 activity due to mutations in Hippo pathway components or YAP1 amplification is observed in several types of human cancers. Here we investigated its genomic b
Externí odkaz:
https://doaj.org/article/e269aebd077c4e9f9859cf224fd87b22
Autor:
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N. Parker, Andreas Boettcher, Christopher J. Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
Publikováno v:
Science Signaling. 16
Inflammasomes are intracellular protein complexes that promote an inflammatory host defense in response to pathogens and damaged or neoplastic tissues and are implicated in inflammatory disorders and therapeutic-induced toxicity. We investigated the
Autor:
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Anna Kostina, Svenja Wöhrle, Stephan Flemming, Larissa Fischer, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian Parker, Andreas Boettcher, Christopher J. Farady, Rolf Backofen, Marta Rodriguez-Franco, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
Inflammasomes are intracellular protein complexes that control proteolytic maturation and secretion of inflammatory interleukin-1 (IL-1) family cytokines and are thus important in host defense. While some inflammasomes are activated simply by binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91918a639a74468417a76d5d58c4b680
https://doi.org/10.1101/2022.02.19.480941
https://doi.org/10.1101/2022.02.19.480941
Autor:
Imtiaz Hossain, Jeremy L. Jenkins, Yann Abraham, Nicholas Holway, Xian Zhang, John A. Tallarico, Christine D. Wilson, Fred Harbinski, Christian N. Parker, Ioannis Moutsatsos, Claudia Agarinis, Luc Dobler
Publikováno v:
Slas Discovery
High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such application
Autor:
Claudia Agarinis, Judith Knehr, Lapo Morelli, Lisa Quinn, Fanning Zeng, Mark Nash, Sven Schuierer, Frederic Bassilana, Guglielmo Roma, Carole Manneville, Isabelle Garnier, Valerie Beck
Publikováno v:
Cells
Volume 9
Issue 12
Cells, Vol 9, Iss 2618, p 2618 (2020)
Volume 9
Issue 12
Cells, Vol 9, Iss 2618, p 2618 (2020)
Genetic knock-in using homology directed repair is an inefficient process, requiring selection of few modified cells and hindering its application to primary cells. Here we describeHomologyindependent geneTagging (HiTag), a method to tag a protein of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7978d34a0a454f0e29ff31bfb8f8c0
Autor:
Ansgar Schuffenhauer, Thomas Nelson, Marie-Cecile Didiot, Frederick J. King, Douglas W. Selinger, Thibault Varin, Hua Wu, Claudia Agarinis, Christian N. Parker
Publikováno v:
ASSAY and Drug Development Technologies. 11:355-366
The use of small molecules to modulate cellular processes is a powerful approach to investigate gene function as a complement to genetic approaches. The discovery and characterization of compounds that modulate translation initiation, the rate-limiti
Autor:
Lorianne Vorlet-Fawer, Matthias D. Sury, Denis Grandgirard, Stephen L. Leib, Claudia Agarinis, Stephan Christen, Shida Yousefi
Publikováno v:
Neurobiology of disease
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Neurobiology of Disease, Vol 41, Iss 1, Pp 201-208 (2011)
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Neurobiology of Disease, Vol 41, Iss 1, Pp 201-208 (2011)
Pneumococcal meningitis causes apoptosis of developing neurons in the dentate gyrus of the hippocampus. The death of these cells is accompanied with long-term learning and memory deficits in meningitis survivors. Here, we studied the role of the PI3K