Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Claudia A. Ryan-Munden"'
Autor:
Stuart C Williamson, Anastasia C Hepburn, Laura Wilson, Kelly Coffey, Claudia A Ryan-Munden, Deepali Pal, Hing Y Leung, Craig N Robson, Rakesh Heer
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48944 (2012)
Stem cells are thought to be the cell of origin in malignant transformation in many tissues, but their role in human prostate carcinogenesis continues to be debated. One of the conflicts with this model is that cancer stem cells have been described t
Externí odkaz:
https://doaj.org/article/89160c47296c454aa6185c80efa065fc
Autor:
Kelly Coffey, Timothy J Blackburn, Susan Cook, Bernard T Golding, Roger J Griffin, Ian R Hardcastle, Lorraine Hewitt, Kety Huberman, Hesta V McNeill, David R Newell, Celine Roche, Claudia A Ryan-Munden, Anna Watson, Craig N Robson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45539 (2012)
Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling. In prostate cancer, aggressive cases over-express Tip60 which functions as a
Externí odkaz:
https://doaj.org/article/ad0f8a29724847c78bbacae4be080277
Autor:
Luke Gaughan, Kanagasabai Sahadevan, Dominic Jones, Alejandra Mantilla, Jacqueline Stockley, Steven Darby, Lynsey Rogerson, Dhuha Alkharaif, Kelly Coffey, Peter Staller, Rakesh Heer, Craig N. Robson, Claudia A. Ryan-Munden, Daniel O'Neill
Publikováno v:
Nucleic Acids Research
The androgen receptor (AR) is a key molecule involved in prostate cancer (PC) development and progression. Post-translational modification of the AR by co-regulator proteins can modulate its transcriptional activity. To identify which demethylases mi
Autor:
Urszula L, McClurg, David M W, Cork, Steven, Darby, Claudia A, Ryan-Munden, Sirintra, Nakjang, Leticia, Mendes Côrtes, Achim, Treumann, Luke, Gaughan, Craig N, Robson
Publikováno v:
Nucleic Acids Research
The androgen receptor (AR) is the main driver of prostate cancer (PC) development and progression, and the primary therapeutic target in PC. To date, two functional ubiquitination sites have been identified on AR, both located in its C-terminal ligan
Autor:
Anna Watson, Claudia A. Ryan-Munden, Ian R. Hardcastle, Bernard T. Golding, Craig N. Robson, Hesta McNeill, Lorraine Hewitt, Kety Huberman, Susan Cook, Kelly Coffey, Roger J. Griffin, David R. Newell, Celine Roche, Timothy J. Blackburn
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e45539 (2012)
PLoS ONE, Vol 7, Iss 10, p e45539 (2012)
Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling. In prostate cancer, aggressive cases over-express Tip60 which functions as a