Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Claudia A. Krusche"'
Autor:
Larissa Fabritz, Lisa Fortmueller, Katja Gehmlich, Sebastian Kant, Marcel Kemper, Dana Kucerova, Fahima Syeda, Cornelius Faber, Rudolf E. Leube, Paulus Kirchhof, Claudia A. Krusche
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 985 (2024)
Desmoglein-2 mutations are detected in 5–10% of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). Endurance training accelerates the development of the ARVC phenotype, leading to earlier arrhythmic events. Homozygous Dsg2 mutant
Externí odkaz:
https://doaj.org/article/5a5105ab2727484b917460f3f967de2c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Cardiac morphogenesis relies on intricate intercellular signaling. Altered signaling impacts cardiac function and is detrimental to embryonic survival. Here we report an unexpected regulatory role of the desmosomal cell adhesion molecule des
Externí odkaz:
https://doaj.org/article/dc4cad01069749ef8b5965c5b6a52231
Publikováno v:
Cells, Vol 11, Iss 1, p 96 (2021)
Arrhythmogenic cardiomyopathy (AC) is a heritable, potentially lethal disease without a causal therapy. AC is characterized by focal cardiomyocyte death followed by inflammation and progressive formation of connective tissue. The pathomechanisms lead
Externí odkaz:
https://doaj.org/article/902dbe98b9fb48ba9460d2d2a2c2a3bb
Publikováno v:
Scientific reports 11, 21687 (2021). doi:10.1038/s41598-021-00996-y
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific reports 11, 21687 (2021). doi:10.1038/s41598-021-00996-y
Published by Macmillan Publishers Limited, part of Springer Nature, [London]
Published by Macmillan Publishers Limited, part of Springer Nature, [London]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1276bcbbf0ed763c7139f4b44d2f0cf
Autor:
Claudia A. Krusche, Muhammed Gerçek, Rudolf E. Leube, Svenja van der Gaag, Sebastian Kant, Nadine Jennifer Lubos
Publikováno v:
Basic research in cardiology 115(4), 42 (2020). doi:10.1007/s00395-020-0803-5
Basic Research in Cardiology
Basic Research in Cardiology
Basic research in cardiology 115(4), 1-19 (2020). doi:10.1007/s00395-020-0803-5
Published by Springer, Berlin ; Heidelberg
Published by Springer, Berlin ; Heidelberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af8ae339bbaac1289da3e1a81e1d9d0
Autor:
Rudolf E. Leube, Gabriel M. Schacht, Christian Preisinger, Nicolas Schlegel, Claudia A. Krusche, Gernot Sellge, Hanna Ungewiss, Peter Boor, Annika Gross, Michael Meir, Pavel Strnad, Christian Trautwein, Lotta Antonia Pauline Pack, Arnd Heuser, Nurdan Guldiken, Sebastian Kant, Jens Waschke
Publikováno v:
Mucosal Immunology. 11:1630-1639
Desmosomes are the least understood intercellular junctions in the intestinal epithelia and provide cell-cell adhesion via the cadherins desmoglein (Dsg)2 and desmocollin (Dsc)2. We studied these cadherins in Crohn's disease (CD) patients and in newl
Autor:
Sebastian Kant, Rudolf E. Leube, Astrid Kassner, Mustafa Gerçek, Hendrik Milting, Elisa A. Liehn, Muhammed Gerçek, Claudia A. Krusche, Sakine Simsekyilmaz
Publikováno v:
The American Journal of Pathology. 187:752-766
Arrhythmogenic cardiomyopathy (AC) is a hereditary disease leading to sudden cardiac death or heart failure. AC pathology is characterized by cardiomyocyte loss and replacement fibrosis. Our goal was to determine whether cardiomyocytes respond to AC
Publikováno v:
Cardiovascular Research. 109:260-271
Aims Examine the relevance and cause of reduced plakoglobin immunofluorescence in intercalated discs for arrhythmogenic right ventricular cardiomyopathy (ARVC) and ARVC-like disease in mouse and human. Methods and Results Normalized semiquantitative
Autor:
Sabine Eisner, Rudolf E. Leube, Matthias Hodecker, Claudia A. Krusche, Irmgard Classen-Linke, Volker U. Buck
Publikováno v:
Cell and tissue research. 374(2)
The intercellular binding of desmosomal junctions is mediated by cadherins of the desmoglein (Dsg) and desmocollin (Dsc) type. Dsg2 mutant mice with deletion of a substantial segment of the extracellular EC1-EC2 domain, which is believed to participa
Autor:
Joachim Alfer, Katrin Gröting, Henning M. Beier, Claudia A. Krusche, Sabine Moss, Irmgard Classen-Linke
Publikováno v:
Histopathology. 61:955-965
Classen-Linke I, Moss S, Groting K, Beier H M, Alfer J & Krusche C A (2012) Histopathology 61, 955–965 Mammaglobin 1: not only a breast-specific and tumour-specific marker, but also a hormone-responsive endometrial protein Aims: The secretoglobin m