Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Claudia, Trappetti"'
Autor:
Hannah N. Agnew, John M. Atack, Ann R.D. Fernando, Sophie N. Waters, Mark van der Linden, Erin Smith, Andrew D. Abell, Erin B. Brazel, James C. Paton, Claudia Trappetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Streptococcus pneumoniae is capable of randomly switching their genomic DNA methylation pattern between six distinct bacterial subpopulations (A-F) via recombination of a type 1 restriction-modification locus, spnIII. These pneumococcal subpopulation
Externí odkaz:
https://doaj.org/article/00f9c5a9ca204ff1806ac1b264eb13c7
Autor:
Zachary N. Phillips, Claudia Trappetti, Annelies Van Den Bergh, Gael Martin, Ainslie Calcutt, Victoria Ozberk, Patrice Guillon, Manisha Pandey, Mark von Itzstein, W. Edward Swords, James C. Paton, Michael P. Jennings, John M. Atack
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Streptococcus pneumoniae is the most common cause of bacterial illness worldwide. Current vaccines based on the polysaccharide capsule are only effective against a limited number of the >100 capsular serotypes. A universal vaccine based on c
Externí odkaz:
https://doaj.org/article/68f9c1ea19634bfb9653d1784a3d28cf
Autor:
Hannah N. Agnew, Erin B. Brazel, Alexandra Tikhomirova, Mark van der Linden, Kimberley T. McLean, James C. Paton, Claudia Trappetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus pneumoniae is the leading cause of bacterial paediatric meningitis after the neonatal period worldwide, but the bacterial factors and pathophysiology that drive pneumococcal meningitis are not fully understood. In this work, we have ide
Externí odkaz:
https://doaj.org/article/4cc47e2da4fb452bbcb8af1819fdaad2
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis are bacterial species which frequently co-colonise the nasopharynx, but can also transit to the middle ear to cause otitis media. Chronic otitis media is often associated with
Externí odkaz:
https://doaj.org/article/ed39a2af5b964581aa5cfc682c1b8910
Autor:
Maoge Zang, Hugo MacDermott-Opeskin, Felise G. Adams, Varsha Naidu, Jack K. Waters, Ashley B. Carey, Alex Ashenden, Kimberley T. McLean, Erin B. Brazel, Jhih-Hang Jiang, Alessandra Panizza, Claudia Trappetti, James C. Paton, Anton Y. Peleg, Ingo Köper, Ian T. Paulsen, Karl A. Hassan, Megan L. O’Mara, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Antimicrobial resistance is an emerging global health crisis. Consequently, we have a critical need to prolong our current arsenal of antibiotics, in addition to the development of novel treatment options.
Externí odkaz:
https://doaj.org/article/6d0881cf57d441f7bee271a358bfc5d7
Autor:
Felise G. Adams, Claudia Trappetti, Jack K. Waters, Maoge Zang, Erin B. Brazel, James C. Paton, Marten F. Snel, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Acinetobacter baumannii
Externí odkaz:
https://doaj.org/article/d2f790e519254c4ea664f455b0b79ee9
Autor:
Patrick Rosendahl Andreassen, Claudia Trappetti, Vikrant Minhas, Flemming Damgaard Nielsen, Kevin Pakula, James C Paton, Mikkel Girke Jørgensen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008332 (2020)
Pathogens of the Streptococcus genus inhabit many different environmental niches during the course of an infection in a human host and the bacteria must adjust their metabolism according to available nutrients. Despite their lack of the citric-acid c
Externí odkaz:
https://doaj.org/article/c6b52d78a5234b1c8ea20cef99d5566a
Autor:
Alexandra Tikhomirova, Erin B. Brazel, Kimberley T. McLean, Hannah N. Agnew, James C. Paton, Claudia Trappetti
Publikováno v:
Pathogens, Vol 11, Iss 2, p 216 (2022)
The LuxS protein, encoded by luxS, is required for the production of autoinducer 2 (AI-2) in Streptococcus pneumoniae. The AI-2 molecule serves as a quorum sensing signal, and thus regulates cellular processes such as carbohydrate utilisation and bio
Externí odkaz:
https://doaj.org/article/f4e41ea4414940ccb18aec82d37031f1
Autor:
Vikrant Minhas, Richard M. Harvey, Lauren J. McAllister, Torsten Seemann, Anna E. Syme, Sarah L. Baines, James C. Paton, Claudia Trappetti
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Streptococcus pneumoniae is commonly carried asymptomatically in the human nasopharynx, but it also causes serious and invasive diseases such as pneumonia, bacteremia, and meningitis, as well as less serious but highly prevalent infections s
Externí odkaz:
https://doaj.org/article/69ae37afdfd543dd8267aa7a80576f37
Publikováno v:
Trends in Microbiology. 29:768-771
Streptococcus pneumoniae is a major human pathogen that can spread to multiple sites in the body. However, the mechanisms dictating disease spread are not well understood. Here we highlight the importance of carbohydrate utilization systems on pneumo