Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claudia, Schnick"'
Autor:
Kevin D. Augustijn, Eleanor J. Dodson, Anthony J. Wilkinson, Chris J. Janse, Andrew P. Waters, James A. Brannigan, Sarah E. Dobson, Claudia Schnick
Publikováno v:
Protein Science. 18:2578-2591
Malaria, caused by Plasmodium falciparum and related parasites, is responsible for millions of deaths each year, mainly from complications arising from the blood stages of its life cycle. Macrophage migration inhibitory factor (MIF), a protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7601b22e9e18290f97c89837c7cae48
https://doi.org/10.1002/pro.263
https://doi.org/10.1002/pro.263
Autor:
Paul J. McMillan, Ian W. Boucher, Susan E. Akerman, Sylke Müller, Mads Gabrielsen, Andrzej M. Brzozowski, Anthony J. Wilkinson, James A. Brannigan, Claudia Schnick
Publikováno v:
Molecular Microbiology
Plasmodium falciparum possesses a single mitochondrion with a functional electron transport chain. During respiration, reactive oxygen species are generated that need to be removed to protect the organelle from oxidative damage. In the absence of cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d924e14bee9683225c55bac36562a4e
https://doi.org/10.1111/j.1365-2958.2006.05303.x
https://doi.org/10.1111/j.1365-2958.2006.05303.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1459:49-60
When isolated in its monomeric form, subunit c of the proton transporting ATP synthase of Escherichia coli was shown to fold in a hairpin-like structure consisting of two hydrophobic membrane spanning helices and a short connecting hydrophilic loop.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850685503d065e28371e27f3a498eb8f
https://doi.org/10.1016/s0005-2728(00)00112-2
https://doi.org/10.1016/s0005-2728(00)00112-2
Autor:
Sarah E, Dobson, Kevin D, Augustijn, James A, Brannigan, Claudia, Schnick, Chris J, Janse, Eleanor J, Dodson, Andrew P, Waters, Anthony J, Wilkinson
Publikováno v:
Protein Science : A Publication of the Protein Society
Malaria, caused by Plasmodium falciparum and related parasites, is responsible for millions of deaths each year, mainly from complications arising from the blood stages of its life cycle. Macrophage migration inhibitory factor (MIF), a protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1fc319d387e3c59969ec26ce494eff5
https://pubmed.ncbi.nlm.nih.gov/19827093
https://pubmed.ncbi.nlm.nih.gov/19827093
Autor:
Lisa C. Ranford-Cartwright, James A. Brannigan, Quinton L. Fivelman, Shane R. Wilkinson, Anthony J. Wilkinson, Spencer D. Polley, David A. Baker, Claudia Schnick
Publikováno v:
Molecular Microbiology
Malaria pathology is caused by multiplication of asexual parasites within erythrocytes, whereas mosquito transmission of malaria is mediated by sexual precursor cells (gametocytes). Microarray analysis identified glycerol kinase (GK) as the second mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eafa42b58e52ff9096ddc76b48384a4
https://pubmed.ncbi.nlm.nih.gov/19040641
https://pubmed.ncbi.nlm.nih.gov/19040641
Autor:
James A. Brannigan, Christopher Mehlin, Anthony J. Wilkinson, Joseph R. Luft, Garib N. Murshudov, Mark A. Robien, Lori Anderson, Andrzej M. Brzozowski, Claudia Schnick, Eleanor J. Dodson, Wim G. J. Hol
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 61(Pt 9)
Purine metabolism in the parasite Plasmodium has been identified as a promising target for antimalarial therapies. Purine nucleoside phosphorylase (PNP) is part of a salvage pathway for the biosynthesis of purines, which are essential for parasite su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9570d94d6ae25afc5dc242e7ef221607
https://pubmed.ncbi.nlm.nih.gov/16131758
https://pubmed.ncbi.nlm.nih.gov/16131758
Autor:
Claudia Schnick, Anthony J. Wilkinson, Sue Kyes, James A. Brannigan, Andrzej M. Brzozowski, Derek Smith, Ian W. Boucher
Publikováno v:
BMC Structural Biology
BMC Structural Biology, Vol 6, Iss 1, p 20 (2006)
BMC Structural Biology, Vol 6, Iss 1, p 20 (2006)
Background Superoxide dismutases (SODs) are important enzymes in defence against oxidative stress. In Plasmodium falciparum, they may be expected to have special significance since part of the parasite life cycle is spent in red blood cells where the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf1daf81c7e2586a98a3f0935a1568f
http://europepmc.org/articles/PMC1618392
http://europepmc.org/articles/PMC1618392