Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Claudia, Korn"'
Autor:
Uwe Grether, Richard H. Foxton, Sabine Gruener, Claudia Korn, Atsushi Kimbara, Anja Osterwald, Elisabeth Zirwes, Sabine Uhles, Janina Thoele, Nadine Colé, Mark Rogers-Evans, Stephan Röver, Matthias Nettekoven, Rainer E. Martin, Jean-Michel Adam, Jürgen Fingerle, Caterina Bissantz, Wolfgang Guba, André Alker, Anna M. Szczesniak, Ross F. Porter, Tom J. Toguri, Franco Revelant, Agnès Poirier, Camille Perret, Lotte Winther, Antonello Caruso, Filomena Fezza, Mauro Maccarrone, Melanie E. M. Kelly, Sascha Fauser, Christoph Ullmer
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionPreclinical studies suggest that cannabinoid receptor type 2 (CB2R) activation has a therapeutic effect in animal models on chronic inflammation and vascular permeability, which are key pathological features of diabetic retinopathy (DR).
Externí odkaz:
https://doaj.org/article/91d1c3e1c6e44284b2f5d719fd280ff1
Autor:
Claire Fielding, Andrés García-García, Claudia Korn, Stephen Gadomski, Zijian Fang, Juan L. Reguera, José A. Pérez-Simón, Berthold Göttgens, Simón Méndez-Ferrer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The sympathetic nervous system has been shown to respond to stress and activate haematopoietic stem cells. Here they show that cholinergic signals in the bone marrow preserve haematopoietic stem cell quiescence and self-renewal under proliferative st
Externí odkaz:
https://doaj.org/article/a37b394503a547f08085bab8d2e09c03
Autor:
Simon Renders, Arthur Flohr Svendsen, Jasper Panten, Nicolas Rama, Maria Maryanovich, Pia Sommerkamp, Luisa Ladel, Anna Rita Redavid, Benjamin Gibert, Seka Lazare, Benjamin Ducarouge, Katharina Schönberger, Andreas Narr, Manon Tourbez, Bertien Dethmers-Ausema, Erik Zwart, Agnes Hotz-Wagenblatt, Dachuan Zhang, Claudia Korn, Petra Zeisberger, Adriana Przybylla, Markus Sohn, Simon Mendez-Ferrer, Mathias Heikenwälder, Maik Brune, Daniel Klimmeck, Leonid Bystrykh, Paul S. Frenette, Patrick Mehlen, Gerald de Haan, Nina Cabezas-Wallscheid, Andreas Trumpp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Haematopoietic stem cells (HSCs) are characterized by their self-renewal potential and associated dormancy. Here the authors show that niche produced netrin-1 preserves HSC quiescence and self-renewal via neogenin-1, and that decline of netrin-1 prod
Externí odkaz:
https://doaj.org/article/3c2f87ae1c244f13b1b1ad0a9daad872
Autor:
Samuel Ruiz de Martín Esteban, Irene Benito-Cuesta, Itziar Terradillos, Ana M. Martínez-Relimpio, M. Andrea Arnanz, Gonzalo Ruiz-Pérez, Claudia Korn, Catarina Raposo, Roman C. Sarott, Matthias V. Westphal, Izaskun Elezgarai, Erick M. Carreira, Cecilia J. Hillard, Uwe Grether, Pedro Grandes, M. Teresa Grande, Julián Romero
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The distribution and roles of the cannabinoid CB2 receptor in the CNS are still a matter of debate. Recent data suggest that, in addition to its presence in microglial cells, the CB2 receptor may be also expressed at low levels, yet biologically rele
Externí odkaz:
https://doaj.org/article/971c3ccb7b28416a96223192611a4cd6
Autor:
Simón Méndez-Ferrer, Claudia Korn
Publikováno v:
HemaSphere, Vol 2, Pp 139-142 (2018)
Externí odkaz:
https://doaj.org/article/ce84d6c2acf44501882ed0a1fde3f1b9
Autor:
Caroline Schreiber, Supriya Saraswati, Shannon Harkins, Annette Gruber, Natascha Cremers, Wilko Thiele, Melanie Rothley, Diana Plaumann, Claudia Korn, Olivier Armant, Hellmut G Augustin, Jonathan P Sleeman
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008216 (2019)
ASAP1 is a multi-domain adaptor protein that regulates cytoskeletal dynamics, receptor recycling and intracellular vesicle trafficking. Its expression is associated with poor prognosis for a variety of cancers, and promotes cell migration, invasion a
Externí odkaz:
https://doaj.org/article/dda25dc10fb74d3d87b9cf2c4d31dbaf
Autor:
Soniya Savant, Silvia La Porta, Annika Budnik, Katrin Busch, Junhao Hu, Nathalie Tisch, Claudia Korn, Aida Freire Valls, Andrew V. Benest, Dorothee Terhardt, Xianghu Qu, Ralf H. Adams, H. Scott Baldwin, Carmen Ruiz de Almodóvar, Hans-Reimer Rodewald, Hellmut G. Augustin
Publikováno v:
Cell Reports, Vol 12, Iss 11, Pp 1761-1773 (2015)
Tie1 is a mechanistically poorly characterized endothelial cell (EC)-specific orphan receptor. Yet, Tie1 deletion is embryonic lethal and Tie1 has been implicated in critical vascular pathologies, including atherosclerosis and tumor angiogenesis. Her
Externí odkaz:
https://doaj.org/article/8a8bd19bf7e943c8ba49e7bf3501a59e
Autor:
Carolin Mogler, Matthias Wieland, Courtney König, Junhao Hu, Anja Runge, Claudia Korn, Eva Besemfelder, Katja Breitkopf‐Heinlein, Dorde Komljenovic, Steven Dooley, Peter Schirmacher, Thomas Longerich, Hellmut G Augustin
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 332-338 (2015)
Abstract Liver fibrosis is a reversible wound‐healing response to injury reflecting the critical balance between liver repair and scar formation. Chronic damage leads to progressive substitution of liver parenchyma by scar tissue and ultimately res
Externí odkaz:
https://doaj.org/article/7bcb0a855e6a4acc860092533209ee54
Autor:
Simon Mendez-Ferrer, Elodie Grockowiak, Claudia Korn, Justyna Rak, Adrien Hallou, Veronika Lysenko, Francesca Panvini, Claire Fielding, Matthew Williams, Eman Khatib-Massalha, Zijian Fang, Andrés García-García, Reema Khorshed, Sara González-Antón, Juan Li, E Baxter, Anjali Kusumbe, Bridget Wilkins, Anna Green, Benjamin Simons, Claire Harrison, Anthony Green, Cristina Lo Celso, Alexandre Theocharides
Aging facilitates the expansion of hematopoietic stem cells (HSCs) carrying clonal hematopoiesis (CH)-related somatic mutations and the development of myeloid malignancies, such as myeloproliferative neoplasms (MPNs). While cooperating mutations can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::243ed3a8fd59770858615a3d9f9af8af
https://doi.org/10.21203/rs.3.rs-1875241/v1
https://doi.org/10.21203/rs.3.rs-1875241/v1
Autor:
Carlos Quezada-Ruiz, Liliana P. Paris, Antonia M. Joussen, Claudia Korn, Marco A. Zarbin, Federico Ricci
Publikováno v:
Eye
The angopoietin/tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development and maintenance. Its relevance to clinicians and basic scientists as a potential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2455eb0fdadbcd561e3d8d0f95767354
https://doi.org/10.1038/s41433-020-01377-x
https://doi.org/10.1038/s41433-020-01377-x