Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Claudia, Finamore"'
Autor:
Claudia Finamore, Simona De Marino, Chiara Cassiano, Giuliano Napolitano, Pasquale Rapacciuolo, Silvia Marchianò, Michele Biagioli, Rosalinda Roselli, Cristina Di Giorgio, Carmen Festa, Stefano Fiorucci, Angela Zampella
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
BAR502, a bile acid analogue, is active as dual FXR/GPBAR1 agonist and represents a promising lead for the treatment of cholestasis and NASH. In this paper we report the synthesis and the biological evaluation of a library of hybrid compounds prepare
Externí odkaz:
https://doaj.org/article/66a1ede6d3ce454db68ec5a259f39f5f
Autor:
Bianca Fiorillo, Rosalinda Roselli, Claudia Finamore, Michele Biagioli, Cristina di Giorgio, Martina Bordoni, Paolo Conflitti, Silvia Marchianò, Rachele Bellini, Pasquale Rapacciuolo, Chiara Cassiano, Vittorio Limongelli, Valentina Sepe, Bruno Catalanotti, Stefano Fiorucci, Angela Zampella
Publikováno v:
ACS Omega, Vol 8, Iss 47, Pp 45163-45163 (2023)
Externí odkaz:
https://doaj.org/article/0149ba2d1b3e46bdaa290fce321d9505
Autor:
Claudia Finamore, Carmen Festa, Bianca Fiorillo, Francesco Saverio Di Leva, Rosalinda Roselli, Silvia Marchianò, Michele Biagioli, Lucio Spinelli, Stefano Fiorucci, Vittorio Limongelli, Angela Zampella, Simona De Marino
Publikováno v:
Molecules, Vol 28, Iss 6, p 2840 (2023)
Compounds featuring a 1,2,4-oxadiazole core have been recently identified as a new chemotype of farnesoid X receptor (FXR) antagonists. With the aim to expand this class of compounds and to understand the building blocks necessary to maintain the ant
Externí odkaz:
https://doaj.org/article/57b8d4d3cd4f4f31904254ee4e63efd5
Autor:
Simona De Vita, Claudia Finamore, Maria Giovanna Chini, Gabriella Saviano, Vincenzo De Felice, Simona De Marino, Gianluigi Lauro, Agostino Casapullo, Francesca Fantasma, Federico Trombetta, Giuseppe Bifulco, Maria Iorizzi
Publikováno v:
Plants, Vol 11, Iss 13, p 1671 (2022)
Cannabis sativa L. is a plant belonging to the Cannabaceae family, cultivated for its psychoactive cannabinoid (Δ9-THC) concentration or for its fiber and nutrient content in industrial use. Industrial hemp shows a low Δ9-THC level and is a valuabl
Externí odkaz:
https://doaj.org/article/62228aafb636416eafb2e505de1fd010
Autor:
Adriana Carino, Federica Moraca, Bianca Fiorillo, Silvia Marchianò, Valentina Sepe, Michele Biagioli, Claudia Finamore, Silvia Bozza, Daniela Francisci, Eleonora Distrutti, Bruno Catalanotti, Angela Zampella, Stefano Fiorucci
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by the severe acute respiratory syndrome coronavirus (SARS)-CoV-2. In light of the urgent need to identify novel approaches to be used in the emergency phase, we have emb
Externí odkaz:
https://doaj.org/article/0e136f123f2d4f6ea7322f7f77cc5230
Autor:
Simona De Vita, Maria Giovanna Chini, Gabriella Saviano, Claudia Finamore, Carmen Festa, Gianluigi Lauro, Simona De Marino, Roberto Russo, Carmen Avagliano, Agostino Casapullo, Antonio Calignano, Giuseppe Bifulco, Maria Iorizzi
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1490 (2021)
Natural products have been the main source of bioactive molecules for centuries. We tested the biological profile of two metabolites extracted from Gentiana lutea L. by means of computational techniques and in vitro assays. The two molecules (loganic
Externí odkaz:
https://doaj.org/article/c6a57e78b18740cc9a8bc91af190cfaa
Autor:
Bianca Fiorillo, Rosalinda Roselli, Claudia Finamore, Michele Biagioli, Cristina di Giorgio, Martina Bordoni, Paolo Conflitti, Silvia Marchianò, Rachele Bellini, Pasquale Rapacciuolo, Chiara Cassiano, Vittorio Limongelli, Valentina Sepe, Bruno Catalanotti, Stefano Fiorucci, Angela Zampella
Retinoic acid receptor-related orphan receptor γ-t (RORγt) and GPBAR1, a transmembrane G-protein-coupled receptor for bile acids, are attractive drug targets to develop clinically relevant small modulators as potent therapeutics for autoimmune dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20139e80ca698453b165f13bfb54a221
https://hdl.handle.net/11391/1540453
https://hdl.handle.net/11391/1540453
Autor:
Seyed Mostafa Goldansaz, Carmen Festa, Ester Pagano, Simona De Marino, Claudia Finamore, Olga Alessandra Parisi, Francesca Borrelli, Ali Sonboli, Maria Valeria D’Auria
Publikováno v:
Molecules, Vol 24, Iss 9, p 1684 (2019)
The n-butanolic extract, from an Iranian specimen of Nepeta asterotricha Rech. f. (NABE), displayed anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated J774A.1 macrophages, which reduced nitrites and cytokines production. Bioassay guided
Externí odkaz:
https://doaj.org/article/1d742846dd3345eb9dc18b0593a52a40
Autor:
Claudia Finamore, Giuliana Baronissi, Silvia Marchianò, Francesco Saverio Di Leva, Adriana Carino, Maria Chiara Monti, Vittorio Limongelli, Angela Zampella, Stefano Fiorucci, Valentina Sepe
Publikováno v:
Molecules, Vol 24, Iss 6, p 1043 (2019)
As a cellular bile acid sensor, farnesoid X receptor (FXR) and the membrane G-coupled receptor (GPBAR1) participate in maintaining bile acid, lipid, and glucose homeostasis. To date, several selective and dual agonists have been developed as promisin
Externí odkaz:
https://doaj.org/article/902c71cfe74b4ac3abdea972db5a5b09