Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Claude van der Ley"'
Autor:
Zongye Cai, Siyu Tian, Theo Klein, Ly Tu, Laurie W. Geenen, Thomas Koudstaal, Annemien E. van den Bosch, Yolanda B. de Rijke, Irwin K. M. Reiss, Eric Boersma, Claude van der Ley, Martijn Van Faassen, Ido Kema, Dirk J. Duncker, Karin A. Boomars, Karin Tran-Lundmark, Christophe Guignabert, Daphne Merkus
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Activation of the kynurenine pathway (KP) has been reported in patients with pulmonary arterial hypertension (PAH) undergoing PAH therapy. We aimed to determine KP-metabolism in treatment-naïve PAH patients, investigate its prognostic value
Externí odkaz:
https://doaj.org/article/79f725107d30412dac03fd519e49b69d
Autor:
Annelies Heylen, Yannick Vermeiren, Ido P. Kema, Martijn van Faassen, Claude van der Ley, Debby Van Dam, Peter P. De Deyn
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 615 (2023)
Objectives: Despite distinct clinical profiles, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients share a remarkable portion of pathological features, with a substantial percentage of patients displaying a mixed disease p
Externí odkaz:
https://doaj.org/article/f1641d36fab848f7a537b7c648a30fe7
Autor:
Lianmin Chen, Inge C.L. van den Munckhof, Kiki Schraa, Rob ter Horst, Martijn Koehorst, Martijn van Faassen, Claude van der Ley, Marwah Doestzada, Daria V. Zhernakova, Alexander Kurilshikov, Vincent W. Bloks, Albert K. Groen, Niels P. Riksen, Joost H.W. Rutten, Leo A.B. Joosten, Cisca Wijmenga, Alexandra Zhernakova, Mihai G. Netea, Jingyuan Fu, Folkert Kuipers
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108212- (2020)
Summary: Bile acids (BAs) are implicated in the etiology of obesity-related conditions such as non-alcoholic fatty liver disease. Differently structured BA species display variable signaling activities via farnesoid X receptor (FXR) and Takeda G prot
Externí odkaz:
https://doaj.org/article/f5c4cfa383074f0b833a8d715bdad341
Autor:
Martijn van Faassen, Claude van der Ley, Ido P. Kema, Karin Eijkelenkamp, Rainer Bischoff, Wilhelmina H. A. de Jong
Publikováno v:
Analytical Chemistry, 92(13), 9072-9078. AMER CHEMICAL SOC INC
Analytical Chemistry
Analytical Chemistry
Plasma-free metanephrines and catecholamines are essential markers in the biochemical diagnosis and follow-up of neuroendocrine tumors and inborn errors of metabolism. However, their low circulating concentrations (in the nanomolar range) and poor fr
Autor:
Ido P. Kema, Peter Paul De Deyn, Claude van der Ley, Jana Janssens, Martijn van Faassen, Yannick Vermeiren
Publikováno v:
Neurochemical Research, 45(5), 1191-1201
Neurochemical Research 45 (2020) 5
Neurochemical research
NEUROCHEMICAL RESEARCH, 45(5), 1191-1201. SPRINGER/PLENUM PUBLISHERS
Neurochemical Research
Neurochemical Research 45 (2020) 5
Neurochemical research
NEUROCHEMICAL RESEARCH, 45(5), 1191-1201. SPRINGER/PLENUM PUBLISHERS
Neurochemical Research
Exploring the neurochemical continuum between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) with respect to monoamines and kynurenines in cerebrospinal fluid (CSF) and serum, may be useful to identify possible new research/the
Autor:
Ido P. Kema, Rayoun Ramendra, André Marette, Darakhshan Sohail Ahmed, Laurence Raymond Marchand, Jing Ouyang, Malcolm Finkelman, Jonathan B. Angel, Brandon Fombuena, Claude van der Ley, Jean-Pierre Routy, Yonglong Zhang, John Lin, Petronela Ancuta, Stéphane Isnard, Bertrand Routy, Delphine Planas, Meriem Messaoudene, Thibault V. Varin, Corentin Richard
Publikováno v:
Open Forum Infectious Diseases
Open Forum Infectious Diseases, 7(9):338. Oxford University Press
Open Forum Infectious Diseases, 7(9):338. Oxford University Press
Background People with HIV (PWH) taking antiretroviral therapy (ART) may experience weight gain, dyslipidemia, increased risk of non-AIDS comorbidities, and long-term alteration of the gut microbiota. Both low CD4/CD8 ratio and chronic inflammation h
Autor:
Ido P. Kema, Johanna M. Geleijnse, Stephan J. L. Bakker, Gerjan Navis, Else van den Berg, Ineke J. Riphagen, Anna van der Veen, Isidor Minović, António W Gomes-Neto, Claude van der Ley, Martijn van Faassen, Manfred Eggersdorfer
Publikováno v:
American Journal of Clinical Nutrition, 106(6), 1366-1374. Oxford University Press
The American journal of clinical nutrition 106 (2017) 6
The American journal of clinical nutrition, 106(6), 1366-1374
The American journal of clinical nutrition 106 (2017) 6
The American journal of clinical nutrition, 106(6), 1366-1374
Background: Low plasma concentrations of pyridoxal 5'-phosphate (PLP) are common in renal transplant recipients (RTRs) and confer increased risk of long-term mortality. To our knowledge, it is not known whether low plasma PLP concentrations have func
Autor:
Ido P. Kema, André Marette, Claude van der Ley, Brandon Frombuena, Thibaut Varin, John Lin, Jean-Pierre Routy, Jonathan B. Angel, Meriem Messaoudene, Bertrand Routy, Petronela Ancuta, Delphine Planas, Stéphane Isnard
Publikováno v:
Cancer Research. 80:PR04-PR04
Background: Persisting inflammation is associated with increased risk of comorbidities and cancer development in people living with HIV (PLWH) under antiretroviral therapy (ART). Indeed, our observations show that a low CD4/CD8 ratio is predictive of
Autor:
Ido P. Kema, Claude van der Ley, Zongye Cai, Daphne Merkus, Martijn van Faassen, Dirk J. Duncker
Publikováno v:
European Respiratory Journal, 54. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Autor:
Ido P. Kema, Yannick Vermeiren, Ellen A. A. Nollen, Peter Paul De Deyn, Freek J. H. Sorgdrager, Claude van der Ley, Martijn van Faassen
Publikováno v:
Journal of Neurochemistry 151 (2019) 5
Journal of Neurochemistry, 151(5), 656-668. Blackwell Publishing Ltd
Journal of Neurochemistry
Journal of neurochemistry
Journal of Neurochemistry, 151(5), 656-668
Journal of Neurochemistry, 151(5), 656-668. Blackwell Publishing Ltd
Journal of Neurochemistry
Journal of neurochemistry
Journal of Neurochemistry, 151(5), 656-668
The kynurenine (Kyn) pathway, which regulates neuroinflammation and N‐methyl‐d‐aspartate receptor activation, is implicated in Parkinson’s disease (PD) and Alzheimer’s disease (AD). Age‐related changes in Kyn metabolism and altered cerebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069147d6e5d34efbad985448ca4b5613
https://research.wur.nl/en/publications/age-and-disease-specific-changes-of-the-kynurenine-pathway-in-par
https://research.wur.nl/en/publications/age-and-disease-specific-changes-of-the-kynurenine-pathway-in-par