Analysis of plasticizers in PVC medical devices: Performance comparison of eight analytical methods

Autor: Stéphanie Genay, Teuta Eljezi, M. Yessaad, Christine Barthélémy, Claude Vaccher, Frédéric Feutry, Régis Cueff, Marie Lecoeur, C Verlhac, Philip Chennell, T. Radaniel, Bertrand Décaudin, Pascal Odou, Morgane Masse, Bruno Jorge Pereira, Nicolas Kambia, Valérie Sautou, C. Breysse, Thierry Dine, Nicolas Simon, Daniel Bourdeaux, Lise Bernard, Nathalie Azaroual

Publikováno v: Talanta
Talanta, 2017, 162, pp.604-611. ⟨10.1016/j.talanta.2016.10.033⟩
Talanta, Elsevier, 2017, 162, pp.604-611. ⟨10.1016/j.talanta.2016.10.033⟩

International audience; A wide variety of medical devices (MDs) used in hospitals are made of flexible plasticized polyvinylchloride (PVC). Different plasticizers are present in variable amounts in the PVC matrix of the devices and can leach out into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadc688a5dfd9ebb2d5319fb474ab3c0
https://doi.org/10.1016/j.talanta.2016.10.033

Quantitative analysis of drugs in biological matrices by HPLC hyphenated to fluorescence detection

Autor: Emmanuelle Lipka, Claude Vaccher

Publikováno v: Bioanalysis. 7:743-762

An overview of the state-of-the art in HPLC coupled with fluorescence detection is presented. Over the last 20 years, the increasing number of methodological papers on this topic (4082 between 1994 and 2004 and 7725 between 2004 and 2014) is testamen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68038cfb7a838a7bc8fd44f1f761c4a3
https://doi.org/10.4155/bio.15.20

Enhanced detection for determination of enantiomeric purity of novel agomelatine analogs by EKC using single and dual cyclodextrin systems

Autor: Claude Vaccher, Emmanuelle Lipka, Saïd Yous, Mohamed Ettaoussi, Elodie Landagaray

Publikováno v: ELECTROPHORESIS. 35:2785-2792

Performing CD-EKC, baseline separation of five agomelatine analogs, potential antidepressant compounds, was achieved. A method for the enantioresolution and determination of enantiomeric purity of these naphthalene derivatives was developed using cap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354585f6f7cce97c9b7a450f1827ee36
https://doi.org/10.1002/elps.201400106

A validated micellar electrokinetic chromatography method for the quantitation of dexamethasone, ondansetron and aprepitant, antiemetic drugs, in organogel

Autor: Florence Bourdon, Marie Lecoeur, Pascal Odou, Marion Duhaut, Claude Vaccher, Catherine Foulon

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 86:40-48

A micellar electrokinetic chromatography (MEKC) method was developed for the determination of three anti-vomiting drugs (aprepitant, dexamethasone and ondansetron) in pharmaceutical formulations. The method was optimized using a central composite des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01d01cefec60d29ab9ef19d95a0390c
https://doi.org/10.1016/j.jpba.2013.07.029

In vitro pharmacokinetic profile of a benzopyridooxathiazepine derivative using rat microsomes and hepatocytes: Identification of phases I and II metabolites

Autor: Claude Vaccher, Marie Lecoeur, Thierry Dine, Nicolas Lebegue, Florence Bourdon, Nicolas Kambia, Valerie Verones, Jean-François Goossens

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 80:69-78

In the present study, the in vitro metabolic behavior of a benzopyridooxathiazepine (BZN), a potent tubulin polymerization inhibitor, was investigated by liquid chromatography-UV detection (LC-UV). First, simple and fast LC-UV methods have been optim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca03596b257f148e9e4d1db5400f194f
https://doi.org/10.1016/j.jpba.2013.02.022