Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Claude Ropars"'
Publikováno v:
Erythrocytes as Drug Carriers in Medicine ISBN: 9781489900463
Red blood cells (RBCs) are easy to obtain, their cellular volume is large enough to load high quantities of active substances and their half-life is well defined. Due to their physiological role, they have access to most parts of the body. If transfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8095e4a7a54f01ff470cb4b6d340d9c1
https://doi.org/10.1007/978-1-4899-0044-9_5
https://doi.org/10.1007/978-1-4899-0044-9_5
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
Ricin is a cytotoxic protein derived from Ricinus Communis, that inhibits eukaryotic protein synthesis.1 Indeed, the catalytic subunit of the toxin, ricin A chain, inactivates eukaryotic ribosomes by removing a single adenine residue from 28S ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0cdb8e13df3699b583bfc1589d702ee
https://doi.org/10.1007/978-1-4615-3030-5_34
https://doi.org/10.1007/978-1-4615-3030-5_34
Autor:
Gérald Guillaumet, Said Jabbouri, Claude Ropars, Jean Claude Maunier, Said Lazar, Sophie Noël-Hocquet
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
In using a reversed hypoosmotic lysis and resealing process, internalization of Naloxone or Naltrexone prodrugs as new opioid antagonists into red blood cells (RBC) can be obtained. We describe the entrapment method and haematological parameters of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b1f5841239279d931fac9703fdd332
https://doi.org/10.1007/978-1-4615-3030-5_27
https://doi.org/10.1007/978-1-4615-3030-5_27
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
Soon after the advent of the diagnostic tool Magnetic Resonance Imaging (MRI), magnetic resonance contrast agents were developed and provided to the radiologists an additional tool that would significantly improve the accuracy of this observation. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b828498988cc7f678a9af8ab562cc3a3
https://doi.org/10.1007/978-1-4615-3030-5_42
https://doi.org/10.1007/978-1-4615-3030-5_42
Autor:
Roger Ktavtzoff, I. Desbois, M. Chassaigne, Philippe Colombat, Jean Pierre Lamagnere, Christian Doinel, Claude Ropars
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
For several years, various enzymes loaded into red blood cells have been tried as circulating bioreactors. However, due to the bacterial or fungal origin of these enzymes, the in vivo use of such a bioreactor is questionable as concerned with potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a18e2d22feac90cf8a9e78ce8432bbc2
https://doi.org/10.1007/978-1-4615-3030-5_21
https://doi.org/10.1007/978-1-4615-3030-5_21
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
A process for large scale incorporation of drugs into red blood cells (RBC) has been developed by Ropars et all, using reversed osmotic lysis inducing transient holes in the RBC membrane. Internalization of inositol hexaphosphate (IHP) in RBC induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ee919e8414bfbc9c31776b0a16a957
https://doi.org/10.1007/978-1-4615-3030-5_3
https://doi.org/10.1007/978-1-4615-3030-5_3
Publikováno v:
The Use of Resealed Erythrocytes as Carriers and Bioreactors ISBN: 9781461363217
The most important role in ethanol metabolism is played in mammals by the liver. It has been calculated that this organ oxidizes about 80% of the ingested ethanol,while the remainder is metabolized at other body sites or it is excreted in breath, uri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2eef96a41cc004d30a316df96863ccb
https://doi.org/10.1007/978-1-4615-3030-5_20
https://doi.org/10.1007/978-1-4615-3030-5_20
Autor:
Paolino Ninfali, Ftlippo Mangani, Claude Ropars, Mauro Magnani, Mirella Laguerre, Luigia Rossi, Marzia Bianchi
Publikováno v:
Scopus-Elsevier
Human erythrocytes were loaded with homogeneous acetaldehyde dehydrogenase (AcDH) purified from Alcaligenes Eutrophus (an enzyme species with an apparent Km for acetaldehyde similar to the mitochondrial enzyme), using an encapsulation procedure based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1d3ed4fd4f4a76715a83789e110428
https://pubmed.ncbi.nlm.nih.gov/2085346
https://pubmed.ncbi.nlm.nih.gov/2085346
Long-term physiological effects of enhanced O2 release by inositol hexaphosphate-loaded erythrocytes
Publikováno v:
Proceedings of the National Academy of Sciences. 84:6894-6898
A continuous lysing and resealing procedure with erythrocytes permitted incorporation in these cells of inositol hexaphosphate (InsP6), a strong allosteric effector of Hb. This leads to significant rightward shifts of the HbO2 dissociation curves wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25390230cc535a9728bbf0ea0779ad53
https://doi.org/10.1073/pnas.84.19.6894
https://doi.org/10.1073/pnas.84.19.6894
Publikováno v:
Journal de Chimie Physique. 65:816-822
I.’existence de quatre complexes hydroxyles du Fe III, Fe(OH)2+ , Fe(OH)+ 2 , Fe2 (OH)5+ et Fe2 (OH)2 4+ , est mise en evidence, tant par potentiometrie que par mesure des temps de relaxation du proton, dans des solutions ferriques, en fonction du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fefd9bec05977be973e49eae5f7d132
https://doi.org/10.1051/jcp/1968650816
https://doi.org/10.1051/jcp/1968650816