Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Claude Rescan"'
Autor:
Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Monica Zhong, Alexandra M. Smink, Bart J. de Haan, Paul de Vos, Kevin Keane, Andreas Vegge, Esther Y. Chen, Wei Song, Wendy F. Liu, James Flanders, Claude Rescan, Lars Groth Grunnet, Xi Wang, Minglin Ma
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demo
Externí odkaz:
https://doaj.org/article/78e679efc4984e719d52d964332bd1c2
Autor:
Violeta Georgieva Tsonkova, Fredrik Wolfhagen Sand, Xenia Asbæk Wolf, Lars Groth Grunnet, Anna Kirstine Ringgaard, Camilla Ingvorsen, Louise Winkel, Mark Kalisz, Kevin Dalgaard, Christine Bruun, Johannes Josef Fels, Charlotte Helgstrand, Sven Hastrup, Fredrik Kryh Öberg, Erik Vernet, Michael Paolo Bastner Sandrini, Allan Christian Shaw, Carsten Jessen, Mads Grønborg, Jacob Hald, Hanni Willenbrock, Dennis Madsen, Rasmus Wernersson, Lena Hansson, Jan Nygaard Jensen, Annette Plesner, Tomas Alanentalo, Maja Borup Kjær Petersen, Anne Grapin-Botton, Christian Honoré, Jonas Ahnfelt-Rønne, Jacob Hecksher-Sørensen, Philippe Ravassard, Ole D. Madsen, Claude Rescan, Thomas Frogne
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 144-157 (2018)
Objective: To characterize the EndoC-βH1 cell line as a model for human beta cells and evaluate its beta cell functionality, focusing on insulin secretion, proliferation, apoptosis and ER stress, with the objective to assess its potential as a scree
Externí odkaz:
https://doaj.org/article/87dc16429b2843beab1b7a3a86b28d77
Autor:
Wanjun Liu, James A. Flanders, Long‐Hai Wang, Qingsheng Liu, Daniel T. Bowers, Kai Wang, Alan Chiu, Xi Wang, Alexander U. Ernst, Kaavian Shariati, Julia S. Caserto, Benjamin Parker, Daqian Gao, Mitchell D. Plesser, Lars G. Grunnet, Claude Rescan, Rodrigo Pimentel Carletto, Louise Winkel, Juan M. Melero‐Martin, Minglin Ma
Publikováno v:
Small
Encapsulation and transplantation of insulin-producing cells offer a promising curative treatment for type 1 diabetes (T1D) without immunosuppression. However, biomaterials used to encapsulate cells often elicit foreign body responses, leading to cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03986a0c38150959d36de6069647cfa8
https://europepmc.org/articles/PMC8881301/
https://europepmc.org/articles/PMC8881301/
Autor:
Wendy Liu, Lars Groth Grunnet, Monica Zhong, Wei Song, Long-Hai Wang, Paul de Vos, Alan Chiu, Esther Y. Chen, Alexandra M. Smink, Bart J. de Haan, Minglin Ma, Qingsheng Liu, Kevin A. Keane, Xi Wang, Duo An, Andreas Vegge, Claude Rescan, James A. Flanders
Publikováno v:
Nature Communications, 10(1):5262. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Foreign body reaction (FBR) to implanted biomaterials and medical devices is common and can compromise the function of implants or cause complications. For example, in cell encapsulation, cellular overgrowth (CO) and fibrosis around the cellular cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b4cffa489284252c75baf96066cb35
https://research.rug.nl/en/publications/3a95d057-b9ca-4ba3-94f2-e47ea5691c1c
https://research.rug.nl/en/publications/3a95d057-b9ca-4ba3-94f2-e47ea5691c1c
Autor:
Emilie Bricout-Neveu, Thomas Frogne, Raphael Scharfmann, Philippe Ravassard, Claude Rescan, Mads Grønborg, Ole D. Madsen, Marc Diedisheim, Olivier Albagli, Signe Ingvarsen, Jeannette S. Kirkegaard
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (3), pp.1109-1113. ⟨10.1172/JCI83573⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.1109-1113. ⟨10.1172/JCI83573⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.1109-1113. 〈10.1172/JCI83573〉
Journal of Clinical Investigation, 2016, 126 (3), pp.1109-1113. ⟨10.1172/JCI83573⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.1109-1113. ⟨10.1172/JCI83573⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.1109-1113. 〈10.1172/JCI83573〉
International audience; It has been reported that endogenous retroviruses can contaminate human cell lines that have been passaged as xenotransplants in immunocompromised mice. We previously developed and described 2 human pancreatic β cell lines (E
Autor:
Rasmus Wernersson, Fredrik Wolfhagen Sand, Charlotte Helgstrand, Kevin Dalgaard, Jacob Hald, Anne Grapin-Botton, Sven Hastrup, Thomas Frogne, Jonas Ahnfelt-Rønne, Ole D. Madsen, Lena Hansson, Erik Vernet, Mark Kalisz, Dennis Madsen, Tomas Alanentalo, Mads Grønborg, Maja Borup Kjær Petersen, Fredrik Kryh Öberg, Michael Paolo Bastner Sandrini, Annette Plesner, Claude Rescan, Christian Honoré, Philippe Ravassard, Carsten Jessen, Louise Winkel, Camilla Ingvorsen, Xenia Asbæk Wolf, Hanni Willenbrock, Jan N. Jensen, Anna Kirstine Ringgaard, Christine Bruun, Violeta Georgieva Tsonkova, Jacob Hecksher-Sørensen, Johannes Josef Fels, Lars Groth Grunnet, Allan Christian Shaw
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2018, 8, pp.144-157. ⟨10.1016/j.molmet.2017.12.007⟩
Molecular Metabolism
Molecular Metabolism, Vol 8, Iss, Pp 144-157 (2018)
Tsonkova, V G, Sand, F W, Wolf, X A, Grunnet, L G, Ringgaard, A K, Ingvorsen, C, Winkel, L, Kalisz, M, Dalgaard, K, Bruun, C, Fels, J J, Helgstrand, C, Hastrup, S, Öberg, F K, Vernet, E, Sandrini, M P B, Shaw, A C, Jessen, C, Grønborg, M, Hald, J, Willenbrock, H, Madsen, D, Wernersson, R, Hansson, L, Jensen, J N, Plesner, A, Alanentalo, T, Petersen, M B K, Grapin-Botton, A, Honoré, C, Ahnfelt-Rønne, J, Hecksher-Sørensen, J, Ravassard, P, Madsen, O D, Rescan, C & Frogne, T 2018, ' The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates ', Molecular Metabolism, vol. 8, pp. 144-157 . https://doi.org/10.1016/j.molmet.2017.12.007
Molecular metabolism, Elsevier, 2018, 8, pp.144-157. ⟨10.1016/j.molmet.2017.12.007⟩
Molecular Metabolism
Molecular Metabolism, Vol 8, Iss, Pp 144-157 (2018)
Tsonkova, V G, Sand, F W, Wolf, X A, Grunnet, L G, Ringgaard, A K, Ingvorsen, C, Winkel, L, Kalisz, M, Dalgaard, K, Bruun, C, Fels, J J, Helgstrand, C, Hastrup, S, Öberg, F K, Vernet, E, Sandrini, M P B, Shaw, A C, Jessen, C, Grønborg, M, Hald, J, Willenbrock, H, Madsen, D, Wernersson, R, Hansson, L, Jensen, J N, Plesner, A, Alanentalo, T, Petersen, M B K, Grapin-Botton, A, Honoré, C, Ahnfelt-Rønne, J, Hecksher-Sørensen, J, Ravassard, P, Madsen, O D, Rescan, C & Frogne, T 2018, ' The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates ', Molecular Metabolism, vol. 8, pp. 144-157 . https://doi.org/10.1016/j.molmet.2017.12.007
Objective To characterize the EndoC-βH1 cell line as a model for human beta cells and evaluate its beta cell functionality, focusing on insulin secretion, proliferation, apoptosis and ER stress, with the objective to assess its potential as a screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb3e641ee305f9db5f81e09f4ed88e7
https://hal.sorbonne-universite.fr/hal-02018209/document
https://hal.sorbonne-universite.fr/hal-02018209/document
Autor:
Christian Honoré, Maja Borup Kjær Petersen, Ole D. Madsen, Claude Rescan, Patrick S. McGrath, T. Klein, S. Østergaard, Jacob Hald, James M. Wells, Mattias Hansson
Publikováno v:
Diabetes, obesitymetabolism. 18
During embryonic development, endocrine cells of the pancreas are specified from multipotent progenitors. The transcription factor Neurogenin 3 (NEUROG3) is critical for this development and it has been shown that all endocrine cells of the pancreas
Autor:
Soraya Hoelper, Jeannette S. Kirkegaard, Jan N. Jensen, Signe Horn, Philip A. Seymour, Mads Grønborg, Jens Høiriis Nielsen, Claude Rescan, Jonas Ahnfelt-Rønne, Marcus Krüger, Ole D. Madsen
Diabetes is characterized by insulin insufficiency due to a relative paucity of functional β-cell mass. Thus, strategies for increasing β-cell mass in situ are sought-after for therapeutic purposes. Pregnancy is a physiological state capable of ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40490b0f35eff35f25bc36ffe3b8ad3c
https://europepmc.org/articles/PMC5414659/
https://europepmc.org/articles/PMC5414659/
Publikováno v:
Gene Expression Patterns, Vol. 11, No 1-2 (2011) pp. 105-11
Epithelial-mesenchymal interactions are critical for normal pancreas development. Fibroblast growth factor (Fgf)-10 is expressed in the pancreatic mesenchyme and its signalling is required for normal growth and regulation of gene expression in the pa
Autor:
Alexandre Coutant, Brice Courselaud, Frédéric Ezan, Anne Bessard, Claude Rescan, Georges Baffet, Christophe Frémin, Gennady Ilyin
Publikováno v:
Hepatology
Hepatology, 2006, 44 (1), pp.152-63. ⟨10.1002/hep.21222⟩
Hepatology, Wiley-Blackwell, 2006, 44 (1), pp.152-63. ⟨10.1002/hep.21222⟩
Hepatology, 2006, 44 (1), pp.152-63. ⟨10.1002/hep.21222⟩
Hepatology, Wiley-Blackwell, 2006, 44 (1), pp.152-63. ⟨10.1002/hep.21222⟩
International audience; We show that MLCK (myosin light chain kinase) plays a key role in cell cycle progression of hepatocytes: either chemical inhibitor ML7 or RNA interference led to blockade of cyclin D1 expression and DNA replication, providing