Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Claude Leclerc"'
Autor:
Gilles Dadaglio, Catherine Fayolle, Marine Oberkampf, Alexandre Tang, Francesc Rudilla, Isabelle Couillin, Eirik A. Torheim, Pierre Rosenbaum, Claude Leclerc
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Antitumor immunity is mediated by Th1 CD4+ and CD8+ T lymphocytes, which induce tumor-specific cytolysis, whereas Th17 CD4+ T cells have been described to promote tumor growth. Here, we explored the influence of IL-17 on the ability of therapeutic va
Externí odkaz:
https://doaj.org/article/5233de5bf6bf40c49d8d32de56bb46e2
Autor:
Marine Oberkampf, Camille Guillerey, Juliette Mouriès, Pierre Rosenbaum, Catherine Fayolle, Alexandre Bobard, Ariel Savina, Eric Ogier-Denis, Jost Enninga, Sebastian Amigorena, Claude Leclerc, Gilles Dadaglio
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cross-presentation allows exogenous antigens to be presented by the major histocompatibility I pathway. Here the authors show that the inducible cross-presentation by plasmacytoid dendritic cells is modulated by mitochondria-originated reactive oxyge
Externí odkaz:
https://doaj.org/article/10dc91008a66480690b43c080dae3057
Autor:
Céline Cousin, Marine Oberkampf, Tristan Felix, Pierre Rosenbaum, Robert Weil, Sylvie Fabrega, Valeria Morante, Donatella Negri, Andrea Cara, Gilles Dadaglio, Claude Leclerc
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1242-1257.e7 (2019)
Summary: Lentiviruses are among the most promising viral vectors for in vivo gene delivery. To overcome the risk of insertional mutagenesis, integrase-deficient lentiviral vectors (IDLVs) have been developed. We show here that strong and persistent s
Externí odkaz:
https://doaj.org/article/066c2f9a277e49c2bf270907fe48d352
Autor:
Alejandra Urrutia, Darragh Duffy, Vincent Rouilly, Céline Posseme, Raouf Djebali, Gabriel Illanes, Valentina Libri, Benoit Albaud, David Gentien, Barbara Piasecka, Milena Hasan, Magnus Fontes, Lluis Quintana-Murci, Matthew L. Albert, Laurent Abel, Andres Alcover, Kalla Astrom, Philippe Bousso, Pierre Bruhns, Ana Cumano, Caroline Demangel, Ludovic Deriano, James Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Antonio Freitas, Odile Gelpi, Ivo Gomperts-Boneca, Serge Hercberg, Olivier Lantz, Claude Leclerc, Hugo Mouquet, Sandra Pellegrini, Stanislas Pol, Lars Rogge, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Vassili Soumelis, Frédéric Tangy, Eric Tartour, Antoine Toubert, Marie-Noëlle Ungeheuer
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2777-2791 (2016)
Systems approaches for the study of immune signaling pathways have been traditionally based on purified cells or cultured lines. However, in vivo responses involve the coordinated action of multiple cell types, which interact to establish an inflamma
Externí odkaz:
https://doaj.org/article/29e815d288914e988aa9c079f47b8846
Autor:
Nada Chaoul, Alexandre Tang, Belinda Desrues, Marine Oberkampf, Catherine Fayolle, Daniel Ladant, Alexander Sainz-Perez, Claude Leclerc
Publikováno v:
OncoImmunology, Vol 7, Iss 3 (2018)
Regulatory T-cells (Tregs) are crucial for the maintenance of immune tolerance and homeostasis as well as for preventing autoimmune diseases, but their impact on the survival of cancer patients remains controversial. In the TC-1 mouse model of human
Externí odkaz:
https://doaj.org/article/372e0cff346f4805a68f729c359e39bc
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
ObjectivesThis study aimed to assess the acceptability and feasibility of a new tailored intervention for informal caregivers: the Ensemble (Together) program.MethodsAn open pre–post within-subject comparison pilot study was conducted. Twenty-one i
Externí odkaz:
https://doaj.org/article/412f75543ec7434c80c68270e82060c1
Autor:
Cindy Bernelin-Cottet, Charlotte Deloizy, Ondrej Stanek, Céline Barc, Edwige Bouguyon, Céline Urien, Olivier Boulesteix, Jérémy Pezant, Charles-Adrien Richard, Mohammed Moudjou, Bruno Da Costa, Luc Jouneau, Christophe Chevalier, Claude Leclerc, Peter Sebo, Nicolas Bertho, Isabelle Schwartz-Cornil
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/c0ef98fc46f1421fb35a91e160ea2bac
Publikováno v:
Behavioral Sciences, Vol 4, Iss 4, Pp 437-447 (2014)
Psychosocial interventions are an essential part of the treatment for people with severe mental illness such as schizophrenia. The criteria regarding what makes an intervention “evidence-based” along with a current list of evidence-based interven
Externí odkaz:
https://doaj.org/article/efa10e38155c4d6e9594e76eaabcfbe5
Autor:
Fadel Sayes, Alexandre Pawlik, Wafa Frigui, Matthias I Gröschel, Samuel Crommelynck, Catherine Fayolle, Felipe Cia, Gregory J Bancroft, Daria Bottai, Claude Leclerc, Roland Brosch, Laleh Majlessi
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005770 (2016)
Mycobacterium tuberculosis (Mtb), possesses at least three type VII secretion systems, ESX-1, -3 and -5 that are actively involved in pathogenesis and host-pathogen interaction. We recently showed that an attenuated Mtb vaccine candidate (Mtb Δppe25
Externí odkaz:
https://doaj.org/article/d8ad9bcf1937474182e449b1af1359d0
Publikováno v:
Bio-Protocol, Vol 6, Iss 12 (2016)
Cytotoxic CD8+ T cells are responsible for the lysis of cells expressing peptides associated with MHC class I molecules and derived from infection with a pathogen or from mutated antigens. In order to quantify in vivo this antigen-specific CD8+ T cel
Externí odkaz:
https://doaj.org/article/6c5a4634b9724eb284894634061ab26d