Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Claude Gagné"'
Autor:
Philippe M. Campeau, Olga Astapova, Rebecca Martins, Jean Bergeron, Patrick Couture, Robert A. Hegele, Todd Leff, Claude Gagné
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1968-1978 (2012)
Familial partial lipodystrophy (FPLD) is characterized by abnormal fat distribution and a metabolic syndrome with hypertriglyceridemia. We identified a family with a severe form of FPLD3 with never-reported clinical features and a novel mutation affe
Externí odkaz:
https://doaj.org/article/bd7cd18df81c44b2b9f7303e01206d9c
Autor:
Jean-Charles Hogue, Benoît Lamarche, André J. Tremblay, Jean Bergeron, Claude Gagné, Patrick Couture
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1336-1342 (2007)
Patients with type 2 diabetes have high levels of triglyceride-rich lipoproteins (TRLs), including apolipoprotein B-48 (apoB-48)-containing TRLs of intestinal origin, but the mechanism leading to overaccumulation of these lipoproteins remains to be f
Externí odkaz:
https://doaj.org/article/59ffcd88385e446395122181e5624f64
Autor:
Jean-Charles Hogue, Benoît Lamarche, Daniel Gaudet, Mathieu Larivière, André J. Tremblay, Jean Bergeron, Isabelle Lemieux, Jean-Pierre Després, Claude Gagné, Patrick Couture
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 6, Pp 1077-1083 (2004)
Small, dense LDL particles have been associated with an increased risk of coronary artery disease, and cholesteryl ester transfer protein (CETP) has been suggested to play a role in LDL particle remodeling. We examined the relationship between LDL he
Externí odkaz:
https://doaj.org/article/a58a572867f24bbfabf2d2386126dfd9
Autor:
André J. Tremblay, Benoît Lamarche, Isabelle L. Ruel, Jean-Charles Hogue, Jean Bergeron, Claude Gagné, Patrick Couture
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 5, Pp 866-872 (2004)
Early radiokinetic studies revealed that the classical metabolic defect in patients with familial hypercholesterolemia (FH) is hypocatabolism of LDL due to decreased LDL receptor activity. However, recent studies have suggested that hepatic oversecre
Externí odkaz:
https://doaj.org/article/49789aff7ec44dd597998e061c4ce3da
Autor:
Isabelle L. Ruel, Patrick Couture, Claude Gagné, Yves Deshaies, Jacques Simard, Robert A. Hegele, Benoît Lamarche
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 8, Pp 1508-1514 (2003)
Individuals with hepatic lipase (HL) deficiency are often characterized by elevated levels of triglycerides (TGs) and cholesterol. The aim of the present study was to characterize the molecular defect leading to severe HL deficiency in a Québec-base
Externí odkaz:
https://doaj.org/article/95091e86aa3b4f8ba29fbf397554b20f
Autor:
Paul D. Martin, Albert Wiegman, urner T, Joel S. Raichlen, Claude Gagné, Marjet J.A.M. Braamskamp, Barbara A. Hutten, Gisle Langslet, Elinor Miller, David Cassiman, Evan A. Stein, Katherine M. Morrison, Brian W. McCrindle, Daniel Gaudet, D. M. Kusters, Gordon A. Francis, Kastelein Jjp
Publikováno v:
Circulation, 136(4), 359-366. Lippincott Williams and Wilkins
Background: Heterozygous familial hypercholesterolemia (HeFH) is an autosomal dominant disorder leading to premature atherosclerosis. Children with HeFH exhibit early signs of atherosclerosis manifested by increased carotid intima-media thickness (IM
Autor:
Gerald F. Watts, Jean Bergeron, G.B. John Mancini, Paolo Raggi, Jack V. Tu, Robert A. Hegele, Milan Gupta, Sumayah Aljenedil, Jing Pang, Robert Dufour, Alexandre M. Bélanger, Jiri Frohlich, Patrick Couture, David Bewick, Brian W. McCrindle, Claude Gagné, Alexis Baass, Jacques Genest, James M. Brophy, Gordon A. Francis, Liam R. Brunham, Isabelle Ruel, Diane Brisson, Jean Grégoire, Zuhier Awan, Daniel Gaudet
Publikováno v:
The Canadian journal of cardiology. 34(9)
Familial hypercholesterolemia (FH) is an autosomal codominant lipoprotein disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C) and high risk of premature atherosclerotic cardiovascular disease. Definitions for FH rely on com
Autor:
Gordon A. Francis, Joel S. Raichlen, Gisle Langslet, John J.P. Kastelein, Daniel Gaudet, Claude Gagné, Paul D. Martin, Albert Wiegman, Elinor Miller, Evan A. Stein, Barbara A. Hutten, Katherine M. Morrison, Traci Turner, David Cassiman, Brian W. McCrindle, D. Meeike Kusters, Marjet J. A. M. Braamskamp
Publikováno v:
Circulation, 137(6), 641-642. Lippincott Williams and Wilkins
We appreciate the comments of Dr Koh regarding our recent publication in Circulation .1 We comment here on the issues raised. Undoubtedly, patients with heterozygous familial hypercholesterolemia (HeFH) should be treated with lipid-lowering medicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9a1f6939b295d75f69dbefa13f3692
https://pure.amc.nl/en/publications/response-by-kusters-et-al-to-letter-regarding-article-effect-of-rosuvastatin-on-carotid-intimamedia-thickness-in-children-with-heterozygous-familial-hypercholesterolemia-the-charon-study-hypercholesterolemia-in-children-and-adolescents-taking-rosuvastatin-open-label(c3603f9c-8c73-4853-90a2-ca4c723db5b6).html
https://pure.amc.nl/en/publications/response-by-kusters-et-al-to-letter-regarding-article-effect-of-rosuvastatin-on-carotid-intimamedia-thickness-in-children-with-heterozygous-familial-hypercholesterolemia-the-charon-study-hypercholesterolemia-in-children-and-adolescents-taking-rosuvastatin-open-label(c3603f9c-8c73-4853-90a2-ca4c723db5b6).html
Autor:
Diane Tribble, Evan A. Stein, Cara East, Wai Chin, Robert Dufour, Joanne M. Donovan, Daniel Gaudet, Mary P. McGowan, Claude Gagné
Publikováno v:
Circulation. 126:2283-2292
Background— Heterozygous familial hypercholesterolemia (HeFH) is a common genetic disorder leading to premature coronary artery disease. Despite statins and additional lipid-lowering therapies, many HeFH patients fail to achieve low-density lipopro
Autor:
Robert A. Hegele, Rebecca Martins, Claude Gagné, Philippe M. Campeau, Jean Bergeron, Todd Leff, Olga Astapova, Patrick Couture
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1968-1978 (2012)
Familial partial lipodystrophy (FPLD) is characterized by abnormal fat distribution and a metabolic syndrome with hypertriglyceridemia. We identified a family with a severe form of FPLD3 with never-reported clinical features and a novel mutation affe