Zobrazeno 1 - 10
of 409
pro vyhledávání: '"Claude Gérard"'
Publikováno v:
Biology, Vol 12, Iss 4, p 612 (2023)
The mammalian cell cycle is governed by a network of cyclin/Cdk complexes which signal the progression into the successive phases of the cell division cycle. Once coupled to the circadian clock, this network produces oscillations with a 24 h period s
Externí odkaz:
https://doaj.org/article/f1f7da13471f4f41a4032f653cbcbb5a
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008854 (2021)
Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs. However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need for alternative targets. To develop a framework for identification
Externí odkaz:
https://doaj.org/article/f0701f2d6cc841c086bc9d2ad2ad8268
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Let-7 microRNA controls the expression of proteins that belong to two distinct gene regulatory networks, namely, a cyclin-dependent kinase (Cdk) network driving the cell cycle and a cell transformation network that can undergo an epigenetic switch be
Externí odkaz:
https://doaj.org/article/ae5c07d1fe134f7bac0bc0a434086df9
Autor:
Didier Gonze, Claude Gérard, Benjamin Wacquier, Aurore Woller, Alen Tosenberger, Albert Goldbeter, Geneviève Dupont
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Noise is pervasive in cellular biology and inevitably affects the dynamics of cellular processes. Biological systems have developed regulatory mechanisms to ensure robustness with respect to noise or to take advantage of stochasticity. We review here
Externí odkaz:
https://doaj.org/article/67cdd465297945e68160cb88552d4526
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 2, p e1004056 (2015)
In present-day eukaryotes, the cell division cycle is controlled by a complex network of interacting proteins, including members of the cyclin and cyclin-dependent protein kinase (Cdk) families, and the Anaphase Promoting Complex (APC). Successful pr
Externí odkaz:
https://doaj.org/article/2bcaaee1ebc94216b725f0c4dff88908
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 1, p e1003455 (2014)
Recently, a molecular pathway linking inflammation to cell transformation has been discovered. This molecular pathway rests on a positive inflammatory feedback loop between NF-κB, Lin28, Let-7 microRNA and IL6, which leads to an epigenetic switch al
Externí odkaz:
https://doaj.org/article/7d1630ca70da4fab9738c0812614e197
Autor:
Claude Gérard, Béla Novák
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83372 (2013)
microRNAs (miRNAs) are small noncoding RNAs that are important post-transcriptional regulators of gene expression. miRNAs can induce thresholds in protein synthesis. Such thresholds in protein output can be also achieved by oligomerization of transcr
Externí odkaz:
https://doaj.org/article/0015c633767648ce9470a98ac7c72877
Autor:
Claude Gérard, Albert Goldbeter
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 5, p e1002516 (2012)
The cell division cycle and the circadian clock represent two major cellular rhythms. These two periodic processes are coupled in multiple ways, given that several molecular components of the cell cycle network are controlled in a circadian manner. F
Externí odkaz:
https://doaj.org/article/61edf0864a0845e98351e37e3a24c718
The presence of a weak oxygen emission at 130.4-nm resulting from the O 3P-3S transition was first detected in limb observations of the Martian aurora with SPICAM/Mars Express (Soret et al., 2016). It is mostly excited by direct impact of energetic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::071adb778fba6911a030b344d6f4bfff
https://doi.org/10.5194/egusphere-egu23-3162
https://doi.org/10.5194/egusphere-egu23-3162
Autor:
Guillaume Sicorello, Bertrand Bonfond, Jean-Claude Gérard, Denis Grodent, Leonardos Gkouvelis, Randy Gladstone, Annika Salveter
The Pedersen ionospheric conductivity at Jupiter can be computed using a precipitated electron flux either obtained by direct in situ measurements or inferred from UV auroral spectra (Gérard et al., 2020). In the latter case, a mono-energetic distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a707fd8b0b5c07eb7f7d520f0b48131
https://doi.org/10.5194/egusphere-egu23-12662
https://doi.org/10.5194/egusphere-egu23-12662