Výsledky vyhledávání - "Claude Desgranges"

The potential impact of CD4+ T cell activation and enhanced Th1/Th2 cytokine ratio on HIV-1 secretion in the lungs of individuals with advanced AIDS and active pulmonary infection

Autor: Jean-Pierre Vendrell, Claude Desgranges, Pierre-Alain Rubbo, Nicolas Nagot, Philippe Van de Perre, Edouard Tuaillon, Arnaud Bourdin, Dominique Israel-Biet, Karine Bollore, Vincent Foulongne

Publikováno v: Clinical Immunology. 139:142-154

Bronchoalveolar lavage fluid (BALF) provides a source of mucosal CD4 + T cells. We investigated the physiological properties of T lymphocytes from BALF and blood and their role on the dynamic of HIV-1 replication among AIDS patients with active lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a62c017dbcaa0248eb2d4af0cc58070
https://doi.org/10.1016/j.clim.2011.01.007

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HTLV-I-associated lymphoma presenting as mycosis fungoides in an HTLV-I non-endemic area: a viro-molecular study

Autor: M. D'incan, M. Gasmi, Claude Desgranges, O. Antoniotti, Y. Fonck, Jacques Chassagne, P. Souteyrand

Publikováno v: British Journal of Dermatology. 132:983-988

Human T-lymphotropic virus type I (HTLV-I) is endemic in the Caribbean region, south-western Japan and Africa, and is associated with tropical spastic paraparesis and adult T-cell leukaemia/lymphoma (ATLL). Cutaneous forms of ATLL are sometimes indis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec34e26492904fd4fc69538387bf2692
https://doi.org/10.1111/j.1365-2133.1995.tb16960.x

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Functional Epstein-Barr virus reservoir in plasma cells derived from infected peripheral blood memory B cells

Autor: Claude Desgranges, Jean-Marie Seigneurin, Jean-Pierre Vendrell, Christophe Duperray, Gaël Petitjean, Karine Bollore, Vincent Foulongne, Edouard Tuaillon, Yassine Al Tabaa

Publikováno v: Blood. 113:604-611

The Epstein-Barr virus (EBV) causes infectious mononucleosis, establishes latency in resting memory B lymphocytes, and is involved in oncogenesis through poorly understood mechanisms. The EBV lytic cycle is initiated during plasma cell differentiatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016a7ad8b99932082f0531d11d991e37
https://doi.org/10.1182/blood-2008-02-136903

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adrenergic relaxation in pulmonary arteries: preservation of the endothelial nitric oxide-dependent 2 component in pulmonary hypertension

Autor: Alain P. Gadeau, Véronique Leblais, Nadège Bellance, Fleur Fresquet, Estelle Delannoy, Sebastien Banquet, Hugues Begueret, Claude Desgranges, Cécile Allières, Bernard Muller, Lionel Leroux

Publikováno v: Cardiovascular Research. 77:202-210

beta-adrenoceptor (beta-AR)-mediated relaxation was characterized in pulmonary arteries from normoxic and hypoxic (as model of pulmonary hypertension) mice. The endothelial NO synthase (eNOS) pathway was especially investigated because of its potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d54f9708f51983a469b7e9250669078
https://doi.org/10.1093/cvr/cvm008

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Autocrine expression of osteopontin contributes to PDGF-mediated arterial smooth muscle cell migration

Autor: Sandra Jalvy, Claude Desgranges, Laetitia Lam Shang Leen, Jacques Bonnet, Marie-Ange Renault, Isabelle Belloc, Alain-Pierre Gadeau

Publikováno v: Cardiovascular Research. 75:738-747

Objective Migration of smooth muscle cells (SMCs) from the media to the intima of arteries is involved in intimal thickening. The platelet-derived growth factor (PDGF) BB is recognized as a major migratory factor for arterial SMCs both in vitro and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666424ae3acc694d9f269eb8f9c4b785
https://doi.org/10.1016/j.cardiores.2007.05.019

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CREB Mediates UTP-Directed Arterial Smooth Muscle Cell Migration and Expression of the Chemotactic Protein Osteopontin via Its Interaction with Activator Protein-1 Sites

Autor: Claude Desgranges, Sandra Jalvy, Annabel Reynaud, Laetitia Lam Shang Leen, Alain-Pierre Gadeau, Isabelle Belloc, Marie-Ange Renault

Publikováno v: Circulation Research. 100:1292-1299

The transcription factor cAMP responsive element-binding protein (CREB) has been found to be involved in arterial smooth muscle cell (SMC) migration. We previously demonstrated that osteopontin (OPN) expression is a key step for UTP-mediated migratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758c8b005d5e97477da73bd436d94d33
https://doi.org/10.1161/01.res.0000266609.28312.de

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Inhibitory control of TGF‐β1 on the activation of Rap1, CD11b, and transendothelial migration of leukocytes

Autor: Derek Davies, IJsbrand M. Kramer, Mauro Perretti, Andrew Grimshaw, Caroline Basoni, Muriel Nobles, Elisabeth Génot, Claude Desgranges

Publikováno v: The FASEB Journal. 19:1-25

Beta2-integrins are a family of dimeric adhesion molecules expressed on leukocytes. Their capacity to bind ligand is regulated by their state of activation. CD11b, an alphaMbeta2 integrin, is implicated in a number of physiological and pathological e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3085338e9561e7a6eb63e831dd1cdd6
https://doi.org/10.1096/fj.04-3085fje

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Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides

Autor: Bernard A. P. Lafont, Anne-Marie Aubertin, Guillaume Belliard, Valérie Monceaux, Roger Le Grand, Bruno Hurtrel, Sylviane Muller, Emmanuel Moreau, Bernard P. Roques, Claude Desgranges

Publikováno v: Vaccine. 23:1399-1407

The human immunodeficiency virus (HIV) regulatory protein Tat represents an attractive target for developing vaccine strategies. Both humoral and cellular responses against Tat might reduce disease progression by interfering with the deleterious func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ed8f2e98d1156788ff6cc42bbe8f68
https://doi.org/10.1016/j.vaccine.2004.08.037

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UTP Induces Osteopontin Expression through a Coordinate Action of NFκB, Activator Protein-1, and Upstream Stimulatory Factor in Arterial Smooth Muscle Cells

Autor: Isabelle Belloc, Mylène Potier, Lodewijk V. Dekker, Elisabeth Génot, Marie-Ange Renault, Alain-Pierre Gadeau, Sandra Jalvy, Claude Desgranges

Publikováno v: Journal of Biological Chemistry. 280:2708-2713

Osteopontin (OPN) is an important chemokinetic agent for several cell types. Our earlier studies have shown that its expression is essential for uridine triphosphate (UTP)-mediated migration of vascular smooth muscle cells. We demonstrated previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7a067f7ab2c8f8bb5ccbf8021cef72
https://doi.org/10.1074/jbc.m411786200

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The Caveolin-1 Binding Domain of HIV-1 Glycoprotein gp41 Is an Efficient B Cell Epitope Vaccine Candidate against Virus Infection

Autor: Sylviane Muller, Stéphane Ferris, Claude Desgranges, Bernard Krust, Hayet Dali, Josette Svab, Jean Paul Briand, Ara G. Hovanessian, Elias A. Said

Publikováno v: Immunity. 21(5):617-627

Caveolin-1 is a scaffolding protein that organizes and concentrates specific ligands within the caveolae membranes. We identified a conserved caveolin-1 binding motif in the HIV-1 transmembrane envelope glycoprotein gp41 and designed several syntheti

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