Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Claude Carnaud"'
Autor:
Saci Iken, Véronique Bachy, Pauline Gourdain, Annick Lim, Sylvie Grégoire, Thomas Chaigneau, Pierre Aucouturier, Claude Carnaud
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002216 (2011)
Several hurdles must be overcome in order to achieve efficient and safe immunotherapy against conformational neurodegenerative diseases. In prion diseases, the main difficulty is that the prion protein is tolerated as a self protein, which prevents p
Externí odkaz:
https://doaj.org/article/ca32df08f9c447578cb0a726c547035d
Autor:
Véronique Bachy, Claude Carnaud
Publikováno v:
Bulletin de l'Académie Vétérinaire de France. 164:105-112
Prion diseases belong to the family of neurodegenerative disorders. They are characterized by the presence, in the central nervous system, of host proteins that by changing conformation and forming soluble multimeric aggregates, and fibrillar amyloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0270352501b61d2dcb4ee70730c55f1a
https://doi.org/10.4267/2042/48075
https://doi.org/10.4267/2042/48075
Autor:
Claude Carnaud, Véronique S. Bachy
Publikováno v:
Prion. 4:66-71
Prion diseases are neurodegenerative conditions caused by the transconformation of a normal host glycoprotein, the cellular prion protein (PrPc) into a neurotoxic, self-aggregating conformer (PrPSc). TSEs are ineluctably fatal and no treatment is yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279e5e53e9008e5273968110affb4d11
https://doi.org/10.4161/pri.4.2.12597
https://doi.org/10.4161/pri.4.2.12597
Autor:
Véronique Bachy, Claude Carnaud, Isabelle Renault, Gauthier Dorban, Saci Iken, Pierre Aucouturier, Hanna Debiec, Sylvie Grégoire, Pauline Gourdain, Anne-Sophie Bergot, Thomas Chaigneau
Publikováno v:
The Journal of Immunology. 183:6619-6628
There is to date no effective way of preventing or curing neurodegenerative diseases such as Alzheimer disease or transmissible spongiform encephalopathies. The idea of treating those conditions by immunological approaches has progressively emerged o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fb74933fefb2a85a2719f37157c5e9
https://doi.org/10.4049/jimmunol.0804385
https://doi.org/10.4049/jimmunol.0804385
Publikováno v:
Scandinavian Journal of Immunology. 6:1217-1223
Conflicting results have been reported concerning the effect of adult thymectomy (A-Tx) on the mixed lymphocyte reaction (MLR) response. Our purpose was to test the reverse question, namely the effect of A-Tx on the stimulatory capacity of mouse lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99073cd235bc8305378940bb1fa5f6f0
https://doi.org/10.1111/j.1365-3083.1977.tb00360.x
https://doi.org/10.1111/j.1365-3083.1977.tb00360.x
Publikováno v:
The Journal of Immunology. 170:1197-1201
IL-12 is a potent cytokine that impairs the growth of several tumors in vivo in natural as well as in therapeutic conditions. Although IL-12 can enhance a number of immunological antitumor mechanisms, including those mediated by NK cells and CTL, rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a578f319291986e1a20bdf8a59fdf3
https://doi.org/10.4049/jimmunol.170.3.1197
https://doi.org/10.4049/jimmunol.170.3.1197
Publikováno v:
Clinical Immunology. 105:176-184
In a previous study, we showed that nonobese diabetic (NOD) mice, a strain that present an inherited predisposition to develop both spontaneous and induced autoimmune lesions, are susceptible to the induction of experimental autoimmune prostatitis (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42e5dce57bc822c2f0045c54dc3c33f
https://doi.org/10.1006/clim.2002.5281
https://doi.org/10.1006/clim.2002.5281
Publikováno v:
Nature Immunology. 2:1117-1125
The progression of autoimmune diabetes is regulated. We examined here the cellular controls exerted on disease that developed in the BDC2.5 T cell receptor-transgenic model. We found that all BDC2.5 mice with a monoclonal, beta cell-reactive, T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42452f7d2c56954503987914bc01a05c
https://doi.org/10.1038/ni738
https://doi.org/10.1038/ni738
Publikováno v:
Scopus-Elsevier
The onset of autoimmune diabetes is related to defective immune regulation. Recent studies have shown that NK T cells are deficient in number and function in both diabetic patients and nonobese diabetic (NOD) mice. NK T cells, which are CD1d restrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc26ca212f2a9d4e9eed2ece6cd9730d
https://doi.org/10.4049/jimmunol.166.6.3749
https://doi.org/10.4049/jimmunol.166.6.3749