Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Claude Boucheix"'
Autor:
David Machover, Emma Goldschmidt, Wathek Almohamad, Vincent Castagné, Julien Dairou, Christophe Desterke, Léa Gomez, Yann Gaston-Mathé, Claude Boucheix
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract High concentration pyridoxal 5’-phosphate, the cofactor of vitamin B6, potentiates cytotoxicity in cancer cells exposed to 5-fluorouracil (FUra) and folinic acid (FA). We studied the effect of high-dose pyridoxine on antitumor activity of
Externí odkaz:
https://doaj.org/article/dd474b15951249689b5f3b8a1a546569
Publikováno v:
Cancers, Vol 15, Iss 19, p 4751 (2023)
Tspan8 is a member of the tetraspanins family of cell surface molecules. The ability of tetraspanins to organize membrane microdomains with other membrane molecules and interfere with their function suggests that they could act as surface integrators
Externí odkaz:
https://doaj.org/article/ca7d5325fd184368aca2e7b56265476d
Autor:
David Machover, Wathek Almohamad, Vincent Castagné, Christophe Desterke, Léa Gomez, Yann Gaston-Mathé, Claude Boucheix, Emma Goldschmidt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Supplementation of cancer cells exposed to 5-fluorouracil (FUra) and folinic acid (FA) with high concentration pyridoxal 5′-phosphate, the cofactor of vitamin B6, potentiates the cytotoxicity of FUra in a synergistic interaction mode. We r
Externí odkaz:
https://doaj.org/article/e48a6dffbe93495e979f8eb33857f074
Autor:
Hélène Lazareth, Carole Henique, Olivia Lenoir, Victor G. Puelles, Martin Flamant, Guillaume Bollée, Cécile Fligny, Marine Camus, Lea Guyonnet, Corinne Millien, François Gaillard, Anna Chipont, Blaise Robin, Sylvie Fabrega, Neeraj Dhaun, Eric Camerer, Oliver Kretz, Florian Grahammer, Fabian Braun, Tobias B. Huber, Dominique Nochy, Chantal Mandet, Patrick Bruneval, Laurent Mesnard, Eric Thervet, Alexandre Karras, François Le Naour, Eric Rubinstein, Claude Boucheix, Antigoni Alexandrou, Marcus J. Moeller, Cédric Bouzigues, Pierre-Louis Tharaux
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a
Externí odkaz:
https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c3
Autor:
Céline Greco, Anne-Charlotte Ponsen, Stéphanie Leclerc-Mercier, Joël Schlatter, Salvatore Cisternino, Claude Boucheix, Christine Bodemer
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 841 (2022)
Pachyonychia congenita (PC) is a genodermatosis associated with severe painful palmoplantar keratoderma (PPK) and thickened dystrophic nails caused by autosomal dominant-negative mutations in five genes encoding keratins 6A-B-C, 16, and 17. The mecha
Externí odkaz:
https://doaj.org/article/ef9de45ea23947da94a05a042725ac5a
Autor:
Stéphanie Charrin, Roberta Palmulli, Martine Billard, Denis Clay, Claude Boucheix, Guillaume Van Niel, Eric Rubinstein
Publikováno v:
Antibodies, Vol 9, Iss 3, p 29 (2020)
CD63, a member of the tetraspanin superfamily, is used as a marker of late endosomes and lysosome-related organelles, as well as a marker of exosomes. Here, we selected rare isotype variants of TS63 by sorting hybridoma cells on the basis of their hi
Externí odkaz:
https://doaj.org/article/227133207d8e4d74b54b33f6506b5ca9
Autor:
Manale El Kharbili, Muriel Cario, Nicolas Béchetoille, Catherine Pain, Claude Boucheix, Françoise Degoul, Ingrid Masse, Odile Berthier-Vergnes
Publikováno v:
Cancers, Vol 12, Iss 5, p 1297 (2020)
Melanoma is the most aggressive skin cancer with an extremely challenging therapy. The dermal-epidermal junction (DEJ) degradation and subsequent dermal invasion are the earliest steps of melanoma dissemination, but the mechanisms remain elusive. We
Externí odkaz:
https://doaj.org/article/57b79f9540c74fd8923d257a6096e1a7
Autor:
Danielle R. Bond, Richard Kahl, Joshua S. Brzozowski, Helen Jankowski, Crystal Naudin, Mamta Pariyar, Kelly A. Avery-Kiejda, Christopher J. Scarlett, Claude Boucheix, William J. Muller, Leonie K. Ashman, Murray J. Cairns, Séverine Roselli, Judith Weidenhofer
Publikováno v:
Cancers, Vol 12, Iss 4, p 795 (2020)
Breast cancer is the most commonly diagnosed and the second leading cause of cancer-related mortality among women worldwide. miR-518f-5p has been shown to modulate the expression of the metastasis suppressor CD9 in prostate cancer. However, the role
Externí odkaz:
https://doaj.org/article/08d5a2daa1c84be0ba488e7358fb82c9
Autor:
Mathilde Bonnet, Aurélie Maisonial-Besset, Yingying Zhu, Tiffany Witkowski, Gwenaëlle Roche, Claude Boucheix, Céline Greco, Françoise Degoul
Publikováno v:
Cancers, Vol 11, Iss 2, p 179 (2019)
Tetraspanins are exposed at the surface of cellular membranes, which allows for the fixation of cognate antibodies. Developing specific antibodies in conjunction with genetic data would largely contribute to deciphering their biological behavior. In
Externí odkaz:
https://doaj.org/article/e53468c14ec3412683655f2a5a27bcbd
Autor:
Christophe Desterke, Christophe Martinaud, Bernadette Guerton, Lisa Pieri, Costanza Bogani, Denis Clay, Frederic Torossian, Jean-Jacques Lataillade, Hans C. Hasselbach, Heinz Gisslinger, Jean-Loup Demory, Brigitte Dupriez, Claude Boucheix, Eric Rubinstein, Sophie Amsellem, Alessandro M. Vannucchi, Marie-Caroline Le Bousse-Kerdilès
Publikováno v:
Haematologica, Vol 100, Iss 6 (2015)
Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and altered stroma in the bone marrow and spleen. The expression of CD9, a tetraspanin known to parti
Externí odkaz:
https://doaj.org/article/37632c4ec382484d95c0a715c72e94f0